Determination of the Transition-State Entropy for Aggregation Suggests How the Growth of Sickle Cell Hemoglobin Polymers can be Slowed

Journal of Molecular Biology

Volumn 377, Issue 3, 2008, Pages 882-888

  Vekilov, Peter G ^a,b   Galkin, Oleg ^a   Pettitt, B Montgomery ^b   Choudhury, Nihar ^b   Nagel, Ronald L ^c  

^a UNIVERSITY OF HOUSTON   (United States)

^b University of Houston   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

growth rate; hemoglobin S polymerization; hydration layer; sickle cell anemia; transition state entropy

Indexed keywords

HEMOGLOBIN S; POLYMER; WATER;

ARTICLE; CELL AGGREGATION; CELL GROWTH; ENERGY; ENTROPY; HYDROPHOBICITY; KINETICS; MOLECULE; POLYMERIZATION; PRIORITY JOURNAL;

EID: 40649114454     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.01.025     Document Type: Article

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