Ultrastructural co-localization of cochlin and type II collagen in the rat semicircular canal

Neuroscience Letters

Volumn 434, Issue 1, 2008, Pages 104-107

  Mizuta, Kunihiro ^a   Ikezono, Tetsuo ^b   Iwasaki, Satoshi ^a   Arai, Maki ^a   Hashimoto, Yasuyuki ^a   Pawankar, Ruby ^b   Watanabe, Takahiro ^a   Shindo, Susumu ^b   Mineta, Hiroyuki ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

COCH; DFNA9; Hereditary hearing impairment; Immunogold method; Vestibular organ

Indexed keywords

COCHLIN; COLLAGEN TYPE 2;

ANIMAL EXPERIMENT; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HOMEOSTASIS; IMMUNOGOLD LABELING; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SEMICIRCULAR CANAL; SENSORY NERVE CELL; ULTRASTRUCTURE;

ANIMALS; BASEMENT MEMBRANE; COLLAGEN TYPE II; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; HAIR CELLS, AMPULLA; MICROSCOPY, IMMUNOELECTRON; NERVE TISSUE PROTEINS; PROTEINS; RATS; RATS, WISTAR; SEMICIRCULAR CANALS;

EID: 40649112281     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.01.036     Document Type: Article

References (25)

1. Bhattacharya S.K., Annangudi S.P., Salomon R.G., Kuchtey R.W., Peachey N.S., and Crabb J.W. Cochlin deposits in the trabecular meshwork of the glaucomatous DBA/2J mouse. Exp. Eye Res. 80 (2005) 741-744
2. Bhattacharya S.K., Rockwood E.J., Smith S.D., Bonilha V.L., Crabb J.S., Kuchtey R.W., Robertson N.G., Peachey N.S., Morton C.C., and Crabb J.W. Proteomics reveal Cochlin deposits associated with glaucomatous trabecular meshwork. J. Biol. Chem. 280 (2005) 6080-6084
3. Bom S.J., Kemperman M.H., de Kok Y.J., Huygen P.L., Verhagen W.I., Cremers F.P., and Cremers C.W. Progressive cochleovestibular impairment caused by a point mutation in the COCH gene at DFNA9. Laryngoscope 109 (1999) 1525-1530
4. Colombatti A., and Bonaldo P. The superfamily of proteins with von Willebrand factor type A-like domains: one theme common to components of extracellular matrix, homeostasis, cellular adhesion, and defense mechanisms. Blood 77 (1991) 2305-2315
5. Colombatti A., Bonaldo P., and Doliana R. Type A modules: interacting domains found in several non-fibrillar collagens and in other extracellular matrix proteins. Matrix 13 (1993) 297-306
6. de Kok Y.J., Bom S.J., Brunt T.M., Kemperman M.H., van Beusekom E., van der Velde-Visser S.D., Robertson N.G., Morton C.C., Huygen P.L., Verhagen W.I., Brunner H.G., Cremers C.W., and Cremers F.P. A Pro51Ser mutation in the COCH gene is associated with late onset autosomal dominant progressive sensorineural hearing loss with vestibular defects. Hum. Mol. Genet. 8 (1999) 361-366
7. Fransen E., Verstreken M., Verhagen W.I., Wuyts F.L., Huygen P.L., D'Haese P., Robertson N.G., Morton C.C., McGuirt W.T., Smith R.J., Declau F., Van de Heyning P.H., and Van Camp G. High prevalence of symptoms of Meniere's disease in three families with a mutation in the COCH gene. Hum. Mol. Genet. 8 (1999) 1425-1429
8. Grabski R., Szul T., Sasak T., Timpl R., Mayne R., Hicks B., and Sztul E. Mutations in COCH that result in non-syndromic autosomal dominant deafness (DFNA9) affect matrix deposition of cochlin. Hum. Genet. 113 (2003) 406-416
9. Hardingham T.E., and Fosang A.J. Proteoglycans: many forms and many functions. FASEB J. 6 (1992) 861-870
10. Ikezono T., Shindo S., Ishizaki M., Li L., Tomiyama S., Takumida M., Pawankar R., Watanabe A., Saito A., and Yagi T. Expression of cochlin in the vestibular organ of rats. ORL J. Otorhinolaryngol. Relat. Spec. 67 (2005) 252-258
11. Ikezono T., Shindo S., Li L., Omori A., Ichinose S., Watanabe A., Kobayashi T., Pawankar R., and Yagi T. Identification of novel Cochlin isoform in the perilymph: insights to Cochlin function and the pathogenesis of DFNA9. Biochem. Biophys. Res. Commun. 314 (2004) 440-446
12. Kaname H., Yoshihara T., Ishii T., Tatsuoka H., and Chiba T. Ultrastructural and immunocytochemical study of the subepithelial fiber component of the guinea pig inner ear. J. Electron. Microsc. 43 (1994) 394-397
13. Khetarpal U. Autosomal dominant sensorineural hearing loss: further temporal bone findings. Arch. Otolaryngol. Head Neck Surg. 119 (1993) 106-108
14. Khetarpal U. DFNA9 is a progressive audiovestibular dysfunction with a microfibrillar deposit in the inner ear. Laryngoscope 110 (2000) 1379-1384
15. Khetarpal U., Schuknecht H.F., Gacek R.R., and Holmes L.B. Autosomal dominant sensorineural hearing loss: pedigree, audiologic findings and temporal bone findings in tow kindreds. Arch. Otolaryngol. Head Neck Surg. 117 (1991) 1032-1042
16. Manolis E.N., Yandavi N., Nadol Jr. J.B., Eavey R.D., McKenna M., Rosenbaum S., Khetarpal U., Halpin C., Merchant S.N., Duyk G.M., MacRae C., Seidman C.E., and Seidman J.G. A gene for non-syndromic autosomal dominant progressive postlingual sensorineural hearing loss maps to chromosome 14q12-13. Hum. Mol. Genet. 5 (1996) 1047-1050
17. Robertson N.G., Cremers C.W., Huygen P.L., Ikezono T., Krastins B., Kremer H., Kuo S.F., Liberman M.C., Merchant S.N., Miller C.E., Nador Jr. J.B., Sarracino D.A., Verhagen W.I., and Morton C.C. Cochlin immuostaining of inner ear pathologic deposits and proteomic analysis in DFNA9 deafness and vestibular dysfunction. Hum. Mol. Genet. 15 (2006) 1071-1085
18. Robertson N.G., Hamaker S.A., Patriub V., Aster J.C., and Morton C.C. Subcellular localization, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9. J. Med. Genet. 40 (2003) 479-486
19. Robertson N.G., Lu L., Heller S., Merchant S.N., Eavey R.D., McKenna M., Nadol Jr. J.B., Miyamoto R.T., Linthicum Jr. F.H., Lubianca Neto J.F., Hudspeth A.J., Seidman C.E., Morton C.C., and Seidman J.G. Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction. Nat. Genet. 20 (1998) 299-303
20. Robertson N.G., Resendes B.L., Lin J.S., Lee C., Aster J.C., Adams J.C., and Morton C.C. Inner ear localization of mRNA and protein products of COCH, mutated in the sensorineural deafness and vestibular disorder, DFNA9. Hum. Mol. Genet. 10 (2001) 2493-2500
21. Slepecky N.B., Savage J.E., and Yoo T.J. Type II, IX and V collagen in the inner ear. Acta Otolaryngol. 112 (1992) 611-617
22. G. Van Camp, R.J.H. Smith, Hereditary hearing loss homepage, URL: http://webh01.ua.ac.be/hhh/.
23. Verhagen W.I., Huygen P.L., and Bles W. A new autosomal dominant syndrome of idiopathic progressive vestibule-cochlear dysfunction with middle-age onset. Acta Otolaryngol. 112 (1992) 899-906
24. Verhagen W.I., Huygen P.L., Theunissen E.J., and Joosten E.M. Hereditary vestibule-cochlear dysfunction and vascular disorders. J. Neurol. Sci. 92 (1989) 55-63
25. Willott J.F., Bross L.S., and McFadden S. Ameliorative effects of exposing DBA/2J mice to an augmented acoustic environment on histological changes in the cochlea and anteroventral cochlear nucleus. J. Assoc. Res. Otolaryngol. 6 (2005) 234-243