Biocompatibility studies of endothelial cells on a novel calcium phosphate/SiO2-xerogel composite for bone tissue engineering

Biomedical Materials

Volumn 3, Issue 1, 2008, Pages

  Thimm, Benjamin W ^a   Unger, Ronald E ^a   Neumann, Hans Georg ^b   Kirkpatrick, C James ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b DOT GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; BIOMATERIAL; CALCIUM PHOSPHATE; CD31 ANTIGEN; COLLAGEN; CYTOKINE; HYDROXYAPATITE; LIPOPOLYSACCHARIDE; PROTEIN; SILICON DIOXIDE; VASCULAR ENDOTHELIAL CADHERIN; VON WILLEBRAND FACTOR; BONITMATRIX;

ARTICLE; BIOCOMPATIBILITY; BONE TISSUE; CELL ADHESION; CELL LINE; CELL STRUCTURE; CHEMICAL COMPOSITION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; GEL; HUMAN; HUMAN CELL; IMAGE ANALYSIS; IMMUNOCYTOCHEMISTRY; INFLAMMATION; NUCLEOTIDE SEQUENCE; POROSITY; PROTEIN EXPRESSION; TISSUE ENGINEERING; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; VITAL STAIN; XEROGEL; BONE PROSTHESIS; CELL CULTURE; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; MATERIALS TESTING; METHODOLOGY; PHYSIOLOGY;

BONE SUBSTITUTES; CALCIUM PHOSPHATES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; GELS; HUMANS; MATERIALS TESTING; SILICON DIOXIDE; TISSUE ENGINEERING;

EID: 40649107465     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/3/1/015007     Document Type: Article

References (36)

1. Nomi M, Atala A, Coppi P D and Soker S 2002 Principals of neovascularization for tissue engineering Mol. Aspects Med. 23 463-83
2. Freed L E, Vunjak G V, Drinker P A and Langer R 1988 A novel bioreactor based on suspended particles of agarose-immobilized species ASAIO Trans. 34 732-8
3. Cassell O C, Hofer S O, Morrison W A and Knight K R 2002 Vascularisation of tissue-engineered grafts: the regulation of angiogenesis in reconstructive surgery and in disease states Br. J. Plast. Surg. 55 603-10
4. Unger R E, Huang Q, Peters K, Protzer D, Paul D and Kirkpatrick C J 2005 Growth of human cells on polyethersulfone (PES) hollow fiber membranes Biomaterials 26 1877-84
5. Hutmacher D W 2000 Scaffolds in tissue engineering bone and cartilage Biomaterials 21 2529-43
6. Becker P, Teller M, Lüthen F, Nebe B, Bulnheim U, Rychly J and Neumann H-G 2004 BONITmatrix-bone regeneration material for dental application BIOmaterialien 5 10-1
7. Gerber T, Knoblich B, Traykova T, Holzhüter G, Dörfling P, Henkel K-O and Bienengräber V 2001 Entwicklung, in vitro und in vivo Tests eines hochporösen Knochenersatzmaterials Osteologie 10 175-83
8. Ignatius A A, Schmidt C, Kaspar D and Claes L E 2001 In vitro biocompatibility of resorbable experimental glass ceramics for bone substitutes J. Biomed. Mater. Res. 55 285-94
9. Knabe C, Driessens F C, Planell J A, Gildenhaar R, Berger G, Reif D, Fitzner R, Radlanski R J and Gross U 2000 Evaluation of calcium phosphates and experimental calcium phosphate bone cements using osteogenic cultures J. Biomed. Mater. Res. 52 498-508
10. Metsger D S, Driskell T D and Paulsrud J R 1982 Tricalcium phosphate ceramic-a resorbable bone implant: review and current status J. Am. Dent. Assoc. 105 1035-8
11. Bienengräber V, Gerber T, Trykova T, Kundt G and Henkel K-O 2004 Eine innovativ im Sol-Gel-Prozeβ hersgestellte, hochporöse Siliziumoxidkeramik zum Knochenersatz-In vivo Langzeitergebnisse Mat.-wiss. u. Werkstofftech. 35 234-9
12. Hopp M, Rogaschewski S, Krahl T and Biffar R 2005 Klinische Erfahrungen und materialkundliche Aspekte bei der Anwendung eines neuen xerogenen Augmentationsmaterials Implantologie 13 301-15
13. Henkel K-O, Gerber T, Dietrich W and V B 2004 Novel calcium phosphate formula for filling bone defects. Initial in vivo long-term results Mund. Kiefer. Gesichtschir. 5 277-81
14. Unger R E, Krump-Konvalinkova V, Peters K and Kirkpatrick C J 2002 In vitro expression of the endothelial phenotype: comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R Microvasc. Res. 64 384-97
15. Krump-Konvalinkova V, Bittinger F, Unger R E, Peters K, Lehr H A and Kirkpatrick C J 2001 Generation of human pulmonary microvascular endothelial cell lines Lab. Invest. 81 1717-27
16. Jaffe E A, Nachman R L, Becker C G and Minick C R 1973 Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria J. Clin. Invest. 52 2745-56
17. Peters K, Schmidt H, Unger R E, Otto M, Kamp G and Kirkpatrick C J 2002 Software-supported image quantification of angiogenesis in an in vitro culture system: application to studies of biocompatibility Biomaterials 23 3413-9
18. Punshon G, Vara D S, Sales K M, Kidane A G, Salacinski H J and Seifalian A M 2005 Interactions between endothelial cells and a poly(carbonate- silsesquioxane-bridge-urea) urethane Biomaterials 26 6271-9
19. Muller A M, Hermanns M I, Cronen C and Kirkpatrick C J 2002 Comparative study of adhesion molecule expression in cultured human macro- and microvascular endothelial cells Exp. Mol. Pathol. 73 171-80
20. Kirkpatrick C J, Unger R E, Krump-Konvalinkova V, Peters K, Schmidt H and Kamp G 2003 Experimental approaches to study vascularization in tissue engineering and biomaterial applications J. Mater. Sci. Mater. Med. 14 677-81
21. Michiels C 2003 Endothelial cell functions J. Cell Physiol. 196 430-43
22. Henkel K-O, Gerber T, Dietrich W, Kundt G and Bienengräber V 2004 Sol-gel derived calcium phosphate ceramics in treating bone defects-a breakthrough to artificial bone substitutes? An animal study Osteologie 13 57-64
23. Traykova T, Bötcher R, Neumann H-G, Henkel K-O, Bienengräber V and Gerber T 2004 Silica/calcium phosphate sol-gel derived bone grafting material-from animal tests to first clinical experience Key Eng. Mater. 254-256 679-82
24. Bulnheim U, Müller P, Münch K, Klinkenberg D, Neumann H-G and Rychly J 2006 In vitro studies of mesenchymal stem cells on the calcium phosphate xerogel composite BONITmatrix BIOmaterialien 7 56
25. Teller M, Gopp U, Neumann H G and Kuhn K D 2007 Release of gentamicin from bone regenerative materials: an in vitro study J. Biomed. Mater. Res. B Appl. Biomater. 81 23-9
26. Porter A E, Patel N, Skepper J N, Best S M and Bonfield W 2003 Comparison of in vivo dissolution processes in hydroxyapatite and silicon-substituted hydroxyapatite bioceramics Biomaterials 24 4609-20
27. Li P, Ohtsuki C, Kokubo T, Nakanishi K, Soga N and de Groot K 1994 The role of hydrated silica, titania, and alumina in inducing apatite on implants J. Biomed. Mater. Res. 28 7-15
28. Unger R E, Peters K, Wolf M, Motta A, Migliaresi C and Kirkpatrick C J 2004 Endothelialization of a non-woven silk fibroin net for use in tissue engineering: growth and gene regulation of human endothelial cells Biomaterials 25 5137-46
29. Chu C F, Lu A, Liszkowski M and Sipehia R 1999 Enhanced growth of animal and human endothelial cells on biodegradable polymers Biochim. Biophys. Acta 1472 479-85
30. Anderson J S, Price T M, Hanson S R and Harker L A 1987 In vitro endothelialization of small-caliber vascular grafts Surgery 101 577-86
31. Kaehler J, Zilla P, Fasol R, Deutsch M and Kadletz M 1989 Precoating substrate and surface configuration determine adherence and spreading of seeded endothelial cells on polytetrafluoroethylene grafts J. Vasc. Surg. 9 535-41
32. Unger R E, Peters K, Huang Q, Funk A, Paul D and Kirkpatrick C J 2005 Vascularization and gene regulation of human endothelial cells growing on porous polyethersulfone (PES) hollow fiber membranes Biomaterials 26 3461-9
33. Santos M I, Fuchs S, Gomes M E, Unger R E, Reis R L and Kirkpatrick C J 2007 Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering Biomaterials 28 240-8
34. Albelda S M, Oliver P D, Romer L H and Buck C A 1990 EndoCAM: a novel endothelial cell-cell adhesion molecule J. Cell Biol. 110 1227-37
35. Albelda S M, Muller W A, Buck C A and Newman P J 1991 Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule J. Cell Biol. 114 1059-68
36. Nachtigal P, Gojova A and Semecky V 2001 The role of epithelial and vascular-endothelial cadherin in the differentiation and maintenance of tissue integrity Acta Med. (Hradec Kralove) 44 83-7