Lack of alterations in thyroid hormones following exposure to polybrominated diphenyl ether 47 during a period of rapid brain development in mice

Drug and Chemical Toxicology

Volumn 31, Issue 2, 2008, Pages 245-254

  Gee, Jillian R ^a,b   Hedge, Joan M ^a   Moser, Virginia C ^a,c  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Brain; Polybrominated diphenyl ether; Postnatal development; Thyroid hormone

Indexed keywords

LIOTHYRONINE; POLYBROMINATED DIPHENYL ETHER; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EXPOSURE VARIABLE; FEMALE; HORMONE ACTION; HORMONE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PERINATAL PERIOD;

ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; HYDROCARBONS, BROMINATED; MALE; MICE; MICE, INBRED C57BL; PHENYL ETHERS; THYROXINE; TIME FACTORS; TRIIODOTHYRONINE;

ANIMALIA; MUS;

EID: 40549136831     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.1080/01480540701873194     Document Type: Article

References (37)

1. Bernard, A., Rousset, P., Dunn, J. T. (2004). Thyroid hormone synthesis and secretion. Thyroid Disease Manager, South Dartmouth, Massachusetts, USA: Endocrine Education Inc.
2. Bocio, A., Llobet, J. M., Domingo, J. L., Corbella, J., Teixido, A., Casas, C. (2003). Polybrominated diphenyl ethers (PBDEs) in foodstuffs: human exposure through the diet. J. Agric. Food Chem. 51:3191-3195.
3. Branchi, I., Alleva, E., Costa, L. G. (2002). Effects of perinatal exposure to a polybrominated diphenyl ether (PBDE 99) on mouse neurobehavioural development. Neurotoxicology 23:375-384.
4. Craft, E. S., DeVito, M. J., Crofton, K. M. (2002). Comparative responsiveness of hypothyroxinemia and hepatic enzyme induction in long-evans rats versus C57BL/6J mice exposed to TCDD-like and phenobarbital-like polychlorinated biphenyl congeners. Toxicol. Sci. 68:372-380.
5. Darnerud P. L., Aune, M., Larsson, L., Hallgren, S. (2004). Serum PBDE levels in exposed rats in relation to effects on thyroxine homeostasis. Organohalogen Compounds 66:3977-3981.
6. Darnerud, P. O., Aune, M., Larsson, L., Hallgren, S. (2007). Plasma PBDE and thyroxine levels in rats exposed to Bromkal or BDE-47. Chemosphere 67:S386-S392.
7. Darnerud, P. O., Eriksen, G. S., Johannesson, T., Larsen, P. B., Viluksela, M. (2001). Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environ. Health Perspect. 109(Suppl 1):49-68.
8. Eriksson, P., Ankarberg, E., Viberg, H., Fredriksson, A. (2001a). The developing cholinergic system as target for environmental toxicants, nicotine, and polychlorinated biphenyls (PCBs): implications for neurotoxicological processes in mice. Neurotox. Res. 3:37-51.
9. Eriksson, P., Fischer, C., Fredriksson, A. (2006). Polybrominated diphenyl ethers, a group of brominated flame retardants, can interact with polychlorinated biphenyls in enhancing developmental neurobehavioral defects. Toxicol. Sci. 94:302-309.
10. Eriksson, P., Jakobsson, E., Fredriksson, A. (2001b). Brominated flame retardants: a novel class of developmental neurotoxicants in our environment? Environ. Health Perspect. 109:903-908.
11. Eriksson, P., Viberg, H., Jakobsson, E., Orn, U., Fredriksson, A. (2002). A brominated flame retardant, 2,2′,4,4′,5-pentabromodiphenyl ether: uptake, retention, and induction of neurobehavioral alterations in mice during a critical phase of neonatal brain development. Toxicol. Sci. 67:98-103.
12. Fischer, D., Hooper, K., Athanasiadou, M., Athanassiadis, I., Bergman, A. (2006). Children show highest levels of polybrominated diphenyl ethers in a California family of four: a case study. Environ. Health Perspect. 114:1581-1584.
13. Fowles, J. R., Fairbrother, A., Baecher-Steppan, L., Kerkvliet, N. I. (1994) Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL6J mice. Toxicology 86:49-61.
14. Hallgren, S., Darnerud, P.O. (2002). Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and chlorinated paraffins (CPs) in rats - testing interactions and mechanisms for thyroid hormone effects. Toxicology 177: 227-243.
15. Hallgren, S., Sinjari, T., Hakansson, H., Darnerud, P. O. (2001). Effects of polybrominated diphenyl ethers (PBDESs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. Arch. Toxicol. 75:200-208.
16. Ira, F. S. (1996). Human Physiology. Chicago: Wm. C. Brown.
17. Jones-Otazo, H. A., Clarke, J. P., Diamond, M. L., Archbold, J. A., Ferguson, G., Harner, T., Richardson, G. M., Ryan, J. J., Wilford, B. (2005) Is house dust the missing exposure pathway for PBDEs? An analysis of the urban fate and human exposure to PBDEs. Environ. Sci. Technol. 39:5121-5130.
18. Kitamura, S., Kato, T., Iida, M., Jinno, N., Suzuki, T., Ohta, S., Fujimoto, N., Hanada, H., Kashiwagi, K., Kashiwagi, A. (2005). Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis. Life Sci. 76:1589-1601.
19. Lorber, M. (2007). Exposure of Americans to polybrominated diphenyl ethers. J. Expo. Sci. Environ. Epidemiol. 18:2-19
20. Macchia, P. E., Takeuchi, Y., Kawai, T., Cua, K., Gauthier, K., Chassande, O., Seo, H., Hayashi, Y., Samarut, J., Murata, Y., Weiss, R. E., Refetoff, S. (2001). Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha. Proc. Natl. Acad. Sci. U S A 98:349-354.
21. McDonald, T. A. (2002). A perspective on the potential health risks of PBDEs. Chemosphere 46:745-755.
22. Rice, D. C., Reeve, E. A., Herlihy, A., Thomas Zoeller, R. T., Thompson, D. W., Markowski, V. P. (2007). Developmental delays and locomotor activity in the C57bl6/J mouse following neonatal exposure to the fully-brominated PBDE, decabromodiphenyl ether. Neurotoxicol. Teratol. 29:511-520.
23. Robbins, J. (1981). Factors altering thyroid hormone metabolism. Environ. Health Perspect. 38:65-70.
24. Smith, J. W., Evans, A. T., Costall, B., Smythe, J. W. (2002) Thyroid hormones, brain function, and cognition: a brief review. Neurosci. Biobehav. Rev. 26:45-60.
25. Staskal, D. F., Diliberto, J. J., Birnbaum, L. S. (2006a). Disposition of BDE 47 in developing mice. Toxicol. Sci. 90:309-316.
26. Staskal, D. F., Diliberto, J. J., Birnbaum, L. S. (2006b). Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. Toxicol. Sci. 89:380-385.
27. Stoker, T. E., Laws, S. C., Crofton, K. M., Hedge, J. M., Ferrell, J. M., Cooper, R. L. (2004). Assessment of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture, in the EDSP male and female pubertal protocols. Toxicol. Sci. 78:144-155.
28. Thuett, K. A., Roots, E. H., Mitchell, L. P., Gentles, B. A., Anderson, T., Kendall, R. J., Smith, E. E. (2002). Effects of in utero and lactational ammonium perchlorate exposure on thyroid gland histology and thyroid and sex hormones in developing deer mice (Peromyscus maniculatus) through postnatal day 21. J. Toxicol. Environ. Health A 65:2119-2130.
29. Viberg, H., Fredriksson, A., Eriksson, P. (2002). Neonatal exposure to the brominated flame retardant 2,2′,4,4′,5-pentabromodiphenyl ether causes altered susceptibility in the cholinergic transmitter system in the adult mouse. Toxicol. Sci. 67:104-107.
30. Viberg, H., Fredriksson, A., Eriksson, P. (2003). Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice. Toxicol. Appl. Pharmacol. 192:95-106.
31. Viberg, H., Fredriksson, A., Eriksson, P. (2004). Investigations of strain and/or gender differences in developmental neurotoxic effects of polybrominated diphenyl ethers in mice. Toxicol. Sci. 81:344-353.
32. Viberg, H., Johansson, N., Fredriksson, A., Eriksson, J., Marsh, G., Eriksson, P. (2006). Neonatal exposure to higher brominated diphenyl ethers, hepta-, octa-, or nonabromodiphenyl ether, impairs spontaneous behavior and learning and memory functions of adult mice. Toxicol. Sci. 92:211-218.
33. Weiss, R. E., Forrest, D., Pohlenz, J., Cua, K., Curran, T., Refetoff, S. (1997). Thyrotropin regulation by thyroid hormone in thyroid hormone receptor beta-deficient mice. Endocrinology 138:3624-3629.
34. Weiss, R. E., Korcarz, C., Chassande, O., Cua, K., Sadow, P. M., Koo, E., Samarut, J., Lang, R. (2002). Thyroid hormone and cardiac function in mice deficient in thyroid hormone receptor-alpha or -beta: an echocardiograph study. Am. J. Physiol. Endocrinol. Metab. 283:E428-E435.
35. Zhou, T., Taylor, M. M., DeVito, M. J., Crofton, K. M. (2002). Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Toxicol. Sci. 66:105-116.
36. Zoeller, R. T., Crofton, K. M. (2000). Thyroid hormone action in fetal brain development and potential for disruption by environmental chemicals. Neurotoxicology 21:935-945.
37. Zoeller, R. T., Rovet, J. (2004). Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings. J. Neuroendocrinol. 16:809-818.