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Volumn 118, Issue 3, 2008, Pages 1006-1016

A single nucleotide mutation in the mouse renin promoter disrupts blood pressure regulation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; RENIN;

EID: 40549119138     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI33824     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 0039964948 scopus 로고    scopus 로고
    • Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice
    • Yanai, K., et al. 2000. Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice. J. Biol. Chem. 275:5-8.
    • (2000) J. Biol. Chem , vol.275 , pp. 5-8
    • Yanai, K.1
  • 2
    • 0030740380 scopus 로고    scopus 로고
    • Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology
    • Clark, A.F., et al. 1997. Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology. J. Biol. Chem. 272:18185-18190.
    • (1997) J. Biol. Chem , vol.272 , pp. 18185-18190
    • Clark, A.F.1
  • 3
    • 0034121853 scopus 로고    scopus 로고
    • Regulation of renin: New evidence from cultured cells and genetically modified mice
    • Bader, M., and Ganten, D. 2000. Regulation of renin: new evidence from cultured cells and genetically modified mice. J. Mol. Med. 78:130-139.
    • (2000) J. Mol. Med , vol.78 , pp. 130-139
    • Bader, M.1    Ganten, D.2
  • 4
    • 0029970918 scopus 로고    scopus 로고
    • Chimeric mice carrying 'regional' targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells
    • Matsusaka, T., et al. 1996. Chimeric mice carrying 'regional' targeted deletion of the angiotensin type 1A receptor gene. Evidence against the role for local angiotensin in the in vivo feedback regulation of renin synthesis in juxtaglomerular cells. J. Clin. Invest. 98:1867-1877.
    • (1996) J. Clin. Invest , vol.98 , pp. 1867-1877
    • Matsusaka, T.1
  • 5
    • 0024296566 scopus 로고
    • Close physical linkage of the murine Ren-1 and Ren-2 loci
    • Abel, K.J., and Gross, K.W. 1988. Close physical linkage of the murine Ren-1 and Ren-2 loci. Nucleic Acids Res. 16:2111-2126.
    • (1988) Nucleic Acids Res , vol.16 , pp. 2111-2126
    • Abel, K.J.1    Gross, K.W.2
  • 6
    • 0025218694 scopus 로고
    • Physical characterization of genetic rearrangements at the mouse renin loci
    • Abel, K.J., and Gross, K.W. 1990. Physical characterization of genetic rearrangements at the mouse renin loci. Genetics. 124:937-947.
    • (1990) Genetics , vol.124 , pp. 937-947
    • Abel, K.J.1    Gross, K.W.2
  • 7
    • 0022343497 scopus 로고
    • Ren-1 and Ren-2 loci are expressed in mouse kidney
    • Field, L.J., and Gross, K.W. 1985. Ren-1 and Ren-2 loci are expressed in mouse kidney. Proc. Natl. Acad. Sci. U. S. A. 82:6196-6200.
    • (1985) Proc. Natl. Acad. Sci. U. S. A , vol.82 , pp. 6196-6200
    • Field, L.J.1    Gross, K.W.2
  • 8
    • 0027405434 scopus 로고
    • Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line
    • Tamura, K., Tanimoto, K., Murakami, K., and Fukamizu, A. 1993. Activation of mouse renin promoter by cAMP and c-Jun in a kidney-derived cell line. Biochim. Biophys. Acta. 1172:306-310.
    • (1993) Biochim. Biophys. Acta , vol.1172 , pp. 306-310
    • Tamura, K.1    Tanimoto, K.2    Murakami, K.3    Fukamizu, A.4
  • 9
    • 0029888518 scopus 로고    scopus 로고
    • Transcriptional induction of the human renin gene by cyclic AMP requires cyclic AMP response element-binding protein (CREB) and a factor binding a pituitary-specific trans-acting factor (Pit-1) motif
    • Germain, S., Konoshita, T., Philippe, J., Corvol, P., and Pinet, F. 1996. Transcriptional induction of the human renin gene by cyclic AMP requires cyclic AMP response element-binding protein (CREB) and a factor binding a pituitary-specific trans-acting factor (Pit-1) motif. Biochem. J. 316:107-113.
    • (1996) Biochem. J , vol.316 , pp. 107-113
    • Germain, S.1    Konoshita, T.2    Philippe, J.3    Corvol, P.4    Pinet, F.5
  • 10
    • 0031026633 scopus 로고    scopus 로고
    • Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both cAMP-responsive element binding protein-1 (CREB)-dependent and CREB-independent mechanisms in Calu-6 cells
    • Ying, L., Morris, B.J., and Sigmund, C.D. 1997. Transactivation of the human renin promoter by the cyclic AMP/protein kinase A pathway is mediated by both cAMP-responsive element binding protein-1 (CREB)-dependent and CREB-independent mechanisms in Calu-6 cells. J. Biol. Chem. 272:2412-2420.
    • (1997) J. Biol. Chem , vol.272 , pp. 2412-2420
    • Ying, L.1    Morris, B.J.2    Sigmund, C.D.3
  • 11
    • 0025201726 scopus 로고
    • Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct
    • Sigmund, C.D., et al. 1990. Isolation and characterization of renin-expressing cell lines from transgenic mice containing a renin-promoter viral oncogene fusion construct. J. Biol. Chem. 265:19916-19922.
    • (1990) J. Biol. Chem , vol.265 , pp. 19916-19922
    • Sigmund, C.D.1
  • 12
    • 11244309604 scopus 로고    scopus 로고
    • Transcriptional regulation of renin: An update
    • Pan, L., and Gross, K.W. 2005. Transcriptional regulation of renin: an update. Hypertension. 45:3-8.
    • (2005) Hypertension , vol.45 , pp. 3-8
    • Pan, L.1    Gross, K.W.2
  • 13
    • 0027443317 scopus 로고
    • Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression
    • Horiuchi, M., Pratt, R.E., Nakamura, N., and Dzau, V.J. 1993. Distinct nuclear proteins competing for an overlapping sequence of cyclic adenosine monophosphate and negative regulatory elements regulate tissue-specific mouse renin gene expression. J. Clin. Invest. 92:1805-1811.
    • (1993) J. Clin. Invest , vol.92 , pp. 1805-1811
    • Horiuchi, M.1    Pratt, R.E.2    Nakamura, N.3    Dzau, V.J.4
  • 14
    • 0034682447 scopus 로고    scopus 로고
    • LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression
    • Tamura, K., et al. 2000. LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression. Proc. Natl. Acad. Sci. U. S. A. 97:8513-8518.
    • (2000) Proc. Natl. Acad. Sci. U. S. A , vol.97 , pp. 8513-8518
    • Tamura, K.1
  • 15
    • 22144463507 scopus 로고    scopus 로고
    • Liver X receptors alpha and beta regulate renin expression in vivo
    • Morello, F., et al. 2005. Liver X receptors alpha and beta regulate renin expression in vivo. J. Clin. Invest. 115:1913-1922.
    • (2005) J. Clin. Invest , vol.115 , pp. 1913-1922
    • Morello, F.1
  • 16
    • 0024558707 scopus 로고
    • Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes
    • Nakamura, N., Burt, D.W., Paul, M., and Dzau, V.J. 1989. Negative control elements and cAMP responsive sequences in the tissue-specific expression of mouse renin genes. Proc. Natl. Acad. Sci. U. S. A. 86:56-59.
    • (1989) Proc. Natl. Acad. Sci. U. S. A , vol.86 , pp. 56-59
    • Nakamura, N.1    Burt, D.W.2    Paul, M.3    Dzau, V.J.4
  • 17
    • 0026602349 scopus 로고
    • Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes
    • Barrett, G., et al. 1992. Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes. Proc. Natl. Acad. Sci. U. S. A. 89:885-889.
    • (1992) Proc. Natl. Acad. Sci. U. S. A , vol.89 , pp. 885-889
    • Barrett, G.1
  • 18
    • 0029120032 scopus 로고
    • In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer
    • Yamada, T., et al. 1995. In vivo identification of a negative regulatory element in the mouse renin gene using direct gene transfer. J. Clin. Invest. 96:1230-1237.
    • (1995) J. Clin. Invest , vol.96 , pp. 1230-1237
    • Yamada, T.1
  • 19
    • 0026741958 scopus 로고
    • A combination of upstream and proximal elements is required for efficient expression of the mouse renin promoter in cultured cells
    • Tamura, K., Tanimoto, K., Murakami, K., and Fukamizu, A. 1992. A combination of upstream and proximal elements is required for efficient expression of the mouse renin promoter in cultured cells. Nucleic Acids Res. 20:3617-3623.
    • (1992) Nucleic Acids Res , vol.20 , pp. 3617-3623
    • Tamura, K.1    Tanimoto, K.2    Murakami, K.3    Fukamizu, A.4
  • 20
    • 0029808405 scopus 로고    scopus 로고
    • Role of proximal promoter elements in regulation of renin gene transcription
    • Petrovic, N., et al. 1996. Role of proximal promoter elements in regulation of renin gene transcription. J. Biol. Chem. 271:22499-22505.
    • (1996) J. Biol. Chem , vol.271 , pp. 22499-22505
    • Petrovic, N.1
  • 21
    • 0035980041 scopus 로고    scopus 로고
    • An Abd-B class HOX.PBX recognition sequence is required for expression from the mouse Ren-1c gene
    • Pan, L., et al. 2001. An Abd-B class HOX.PBX recognition sequence is required for expression from the mouse Ren-1c gene. J. Biol. Chem. 276:32489-32494.
    • (2001) J. Biol. Chem , vol.276 , pp. 32489-32494
    • Pan, L.1
  • 22
    • 0027961018 scopus 로고
    • Mechanism of cAMP regulation of renin gene transcription by proximal promoter
    • Tamura, K., et al. 1994. Mechanism of cAMP regulation of renin gene transcription by proximal promoter. J. Clin. Invest. 94:1959-1967.
    • (1994) J. Clin. Invest , vol.94 , pp. 1959-1967
    • Tamura, K.1
  • 23
    • 20144389040 scopus 로고    scopus 로고
    • Identification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination
    • Shimizu, T., et al. 2005. Identification of cis-regulatory sequences in the human angiotensinogen gene by transgene coplacement and site-specific recombination. Mol. Cell. Biol. 25:2938-2945.
    • (2005) Mol. Cell. Biol , vol.25 , pp. 2938-2945
    • Shimizu, T.1
  • 24
    • 0034704155 scopus 로고    scopus 로고
    • Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus
    • Mullins, L.J., et al. 2000. Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus. J. Biol. Chem. 275:40378-40384.
    • (2000) J. Biol. Chem , vol.275 , pp. 40378-40384
    • Mullins, L.J.1
  • 25
    • 0029833215 scopus 로고    scopus 로고
    • Transgene Coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila
    • Siegal, M.L., and Hartl, D.L. 1996. Transgene Coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila. Genetics. 144:715-726.
    • (1996) Genetics , vol.144 , pp. 715-726
    • Siegal, M.L.1    Hartl, D.L.2
  • 26
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee, E.C., et al. 2001. A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics. 73:56-65.
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1
  • 27
    • 0032541483 scopus 로고    scopus 로고
    • Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination
    • Lee, G., and Saito, I. 1998. Role of nucleotide sequences of loxP spacer region in Cre-mediated recombination. Gene. 216:55-65.
    • (1998) Gene , vol.216 , pp. 55-65
    • Lee, G.1    Saito, I.2
  • 28
    • 0021836189 scopus 로고
    • Studies of the regulation of mouse renin genes by measurement of renin messenger ribonucleic acid
    • Catanzaro, D.F., Mesterovic, N., and Morris, B.J. 1985. Studies of the regulation of mouse renin genes by measurement of renin messenger ribonucleic acid. Endocrinology. 117:872-878.
    • (1985) Endocrinology , vol.117 , pp. 872-878
    • Catanzaro, D.F.1    Mesterovic, N.2    Morris, B.J.3
  • 29
    • 21644466875 scopus 로고    scopus 로고
    • Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type
    • Takahashi, N., et al. 2005. Ren1c homozygous null mice are hypotensive and polyuric, but heterozygotes are indistinguishable from wild-type. J. Am. Soc. Nephrol. 16:125-132.
    • (2005) J. Am. Soc. Nephrol , vol.16 , pp. 125-132
    • Takahashi, N.1
  • 30
    • 0026091235 scopus 로고
    • Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor
    • Horiuchi, M., Nakamura, N., Tang, S.S., Barrett, G., and Dzau, V.J. 1991. Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor. J. Biol. Chem. 266:16247-16254.
    • (1991) J. Biol. Chem , vol.266 , pp. 16247-16254
    • Horiuchi, M.1    Nakamura, N.2    Tang, S.S.3    Barrett, G.4    Dzau, V.J.5
  • 31
    • 0035151678 scopus 로고    scopus 로고
    • Evaluating a model of an NRE mediated tissue-specific expression of murine renin genes
    • Abonia, J.P., et al. 2001. Evaluating a model of an NRE mediated tissue-specific expression of murine renin genes. Hypertension. 37:105-109.
    • (2001) Hypertension , vol.37 , pp. 105-109
    • Abonia, J.P.1
  • 32
    • 0035824520 scopus 로고    scopus 로고
    • Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression
    • Pan, L., et al. 2001. Critical roles of a cyclic AMP responsive element and an E-box in regulation of mouse renin gene expression. J. Biol. Chem. 276:45530-45538.
    • (2001) J. Biol. Chem , vol.276 , pp. 45530-45538
    • Pan, L.1
  • 33
    • 0036448341 scopus 로고    scopus 로고
    • Cyclic AMP stimulates renin gene transcription in juxtaglomerular cells
    • Klar, J., Sandner, P., Muller, M.W., and Kurtz, A. 2002. Cyclic AMP stimulates renin gene transcription in juxtaglomerular cells. Pflugers Arch. 444:335-344.
    • (2002) Pflugers Arch , vol.444 , pp. 335-344
    • Klar, J.1    Sandner, P.2    Muller, M.W.3    Kurtz, A.4
  • 34
    • 0034798317 scopus 로고    scopus 로고
    • Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation
    • Selleri, L., et al. 2001. Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development. 128:3543-3557.
    • (2001) Development , vol.128 , pp. 3543-3557
    • Selleri, L.1
  • 35
    • 33746510900 scopus 로고    scopus 로고
    • Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype
    • Ferretti, E., et al. 2006. Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype. Mol. Cell. Biol. 26:5650-5662.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 5650-5662
    • Ferretti, E.1
  • 37
    • 20144378945 scopus 로고    scopus 로고
    • Activation of the rat renin promoter by HOXD10.PBX1b.PREP1, Ets-1, and the intracellular domain of notch
    • Pan, L., Glenn, S.T., Jones, C.A., and Gross, K.W. 2005. Activation of the rat renin promoter by HOXD10.PBX1b.PREP1, Ets-1, and the intracellular domain of notch. J. Biol. Chem. 280:20860-20866.
    • (2005) J. Biol. Chem , vol.280 , pp. 20860-20866
    • Pan, L.1    Glenn, S.T.2    Jones, C.A.3    Gross, K.W.4
  • 38
    • 0034312291 scopus 로고    scopus 로고
    • Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice
    • Tanimoto, K., Liu, Q., Grosveld, F., Bungert, J., and Engel, J.D. 2000. Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice. Genes Dev. 14:2778-2794.
    • (2000) Genes Dev , vol.14 , pp. 2778-2794
    • Tanimoto, K.1    Liu, Q.2    Grosveld, F.3    Bungert, J.4    Engel, J.D.5
  • 40
    • 0027190950 scopus 로고
    • Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes
    • Fukamizu, A., et al. 1993. Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. J. Biol. Chem. 268:11617-11621.
    • (1993) J. Biol. Chem , vol.268 , pp. 11617-11621
    • Fukamizu, A.1
  • 41
    • 0028152913 scopus 로고
    • Angiotensinogen-deficient mice with hypotension
    • Tanimoto, K., et al. 1994. Angiotensinogen-deficient mice with hypotension. J. Biol. Chem. 269:31334-31337.
    • (1994) J. Biol. Chem , vol.269 , pp. 31334-31337
    • Tanimoto, K.1


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