Aberrant FHIT transcripts in human colorectal cancers

Research Communications in Molecular Pathology and Pharmacology

Volumn 117-118, Issue , 2005, Pages 153-165

  Lee, Sung Ho ^a   Lee, Sang Han ^a  

^a Soonchunhyang University   (South Korea)

Author keywords

Alternative splicing; Cell cycle; Colorectal cancer; Exon; FHIT; FRA3B; NRK 52E cells; Tumor suppressor

Indexed keywords

FRAGILE HISTIDINE TRIAD PROTEIN;

ADULT; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CARCINOGENICITY; CELL CYCLE; CELL PROLIFERATION; CELL TRANSFORMATION; CHROMOSOME 3P; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; EXON; FEMALE; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; INTRON; KIDNEY CELL; MALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SEQUENCE ANALYSIS;

ACID ANHYDRIDE HYDROLASES; ANIMALS; CELL CYCLE; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA, COMPLEMENTARY; EXONS; FLOW CYTOMETRY; HUMANS; KIDNEY; NEOPLASM PROTEINS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 40549116320     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. 3-tri phosphate hydrolase. Biochemistry 35: 11529-11535.
2. Bugert, P., Wilheim, M. and Kovacs, G. (1997). FHIT gene and FRA3B region are not involved in the genetics of renal cell carcinoma. Genes Chromosomes Cancer 20: 9-15.
3. Dulic, V., Kaufman, W.K., Wilson, S., Tisty, T., Lee, E., Harper, J.W., Elledge, S.J. and Reed, S.I. (1994). p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76: 1013-1023.
4. Druck, T., Hadaczek, P. and Fu, T.B. (1997). Structure and expression of the human FHIT gene in normal and tumor cells. Cancer Res. 57: 504-512.
5. Faustino, N.A. and Cooper, T.A. (2003). Pre-mRNA splicing and human diseases. Gene Dev. 17: 419-37.
6. Graveley, B.R. (2001). Alternative splicing: increasing deversity in the proteomic world. Trends Genet. 17: 100-107.
7. Hao, X.P., Willis, J.E., Pretlow, T.G., Rao, J.S., MacLennan, G.T., Talbot, I.C. and Pretlow, T.P. (2000). Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions. Cancer Res. 60: 18-21.
8. Hibi, K., Taguchi, M., Nakamura, H., Hirai, A., Fuiikake, Y., Matsui, T., Kasai, Y., Akiyama, S., Ito, K. and Takagi, H. (1997). Alternative splicing of the FHIT gene in colorectal cancers. Jpn. J. Cancer Res. 88:.385-388.
9. Jemal, A., Murray, T., Ward, E., Samuels, A., Tiwari, R.C., Ghafoor, A., Feuer, E.J. and Thun, M.J. (2005). Cancer Statistics 2005. CA Cancer J. Clin. 55: 10-30.
10. Lee, S.H., Kim, C.J., Park, H.K., Koh, J.W., Cho, M.H, Baek, M.J. and Lee, M.S. (2001). Characterization of aberrant FHIT transcripts in gastric adenocarcinomas. Exp. Mol. Med. 33: 124-130.
11. Lee, S.H, Kim, W.H., Kim, H.K., Woo, K.M., Nam, H.S., Kim, H.S., Kim, J.G. and Cho, M.H. (2001). Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas. Biochem. Biophys. Res. Commun. 284: 850-855.
12. Lukas, J., Gao, D.Q., Keshmeshian, M., Wen, W.H., Tsao-Wei, D., Rosenberg, S. and Press, M.F. (2001). Alternative aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer. Cancer Res. 61: 3212-3219.
13. Man, S., Ellis, I.O., Sibbering, M., Blamey, R.W. and Brook, J.D. (1996). High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers. Cancer Res. 56: 5484-5489.
14. Mitelman, F., Mertens, F. and Johnsson, B. (1997). A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat. Genet. 15: 471-474.
15. Mori, M., Mimori, K., Masuda, T., Yoshinaga, K., Yamashita, K., Matsuyama, A. and Inoue, H. (2001). Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma. Cancer Res. 61: 7379-7382.
16. O'connor, P.M., Ferris, D.K., Pagano, M., Draetta, G., Pines, J., Hunter, T., Longer, D.L. and Kohn, K.W. (1993). G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B/cdc2 kinase complexes differently. J. Biol. Chem. 268:.8298-8308.
17. Ohta, M., Inoue, H., Cotticelli, M.G., Kastury, K., Baffa, R., Palazzo, J., Mori, M., McCue, P., Druck, T., Croce, C.M. and Huebner, K. (1996). The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84: 587-597.
18. Philips, A.V. and Cooper, T.A. (2000). RNA processing and human disease. Cell. Mol. Life Sci. 57: 235-49.
19. Pulak, R. and Anderson, P. (1993). mRNA surveillance by the Caenorhabditis elegans smg genes. Genes Dev. 7: 1885-1897, 1993.
20. Thiagalingam, S., Lisitsyn, N.A., Hamaguchi, M., Wigler, M.H., Wilson, J.K., Markowitz, S.D., Leach, F.S., Kinzler, K.W. and Vogelstein, B. (1996). Evaluation of the FHIT gene in colorectal cancers. Cancer Res. 56: 2936-2941.
21. Wilke, C.M., Hall, B.K., Hoge, A., Paradee, W., Smith, D.I. and Glover, T.W. (1996). FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: Direct evidence for the coincidence of viral integration sites and fragile sites. Hum. Mol. Genet. 5: 978-983.