-
1
-
-
0032488791
-
Fluorescent, sequence-selective peptide detection by synthetic small molecules
-
1. C-T Chen H Wagner WC Still 1998 Fluorescent, sequence-selective peptide detection by synthetic small molecules Science 279 5352 851 853 9452382 10.1126/science.279.5352.851 1:CAS:528:DyaK1cXhtVKqtbY%3D Chen C-T, Wagner H, Still WC, (1998) Fluorescent, sequence-selective peptide detection by synthetic small molecules. Science 279(5352):851–853
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 851-853
-
-
Chen, C-T1
Wagner, H2
Still, WC3
-
2
-
-
0035801512
-
Sensing a paradigm shift in the field of molecular recognition: from selective to differential receptors
-
2. JJ Lavigne EV Anslyn 2001 Sensing a paradigm shift in the field of molecular recognition: from selective to differential receptors Angew Chem, Int Ed 40 17 3119 3130 10.1002/1521-3773(20010903)40:17<3118::AID-ANIE3118>3.0.CO;2-Y Lavigne JJ, Anslyn EV (2001) Sensing a paradigm shift in the field of molecular recognition: from selective to differential receptors. Angew Chem, Int Ed 40(17):3119–3130
-
(2001)
Angew Chem, Int Ed
, vol.40
, Issue.17
, pp. 3119-3130
-
-
Lavigne, JJ1
Anslyn, EV2
-
3
-
-
0035983127
-
Rigidization, preorientation and electronic decoupling—the ‘magic triangle’ for the design of highly efficient fluorescent sensors and switches
-
3. K Rurack U Resch-Genger 2002 Rigidization, preorientation and electronic decoupling—the ‘magic triangle’ for the design of highly efficient fluorescent sensors and switches Chem Soc Rev 31 2 116 127 12109205 10.1039/b100604p 1:CAS:528:DC%2BD38XhvFyjtrk%3D Rurack K, Resch-Genger U (2002) Rigidization, preorientation and electronic decoupling—the ‘magic triangle’ for the design of highly efficient fluorescent sensors and switches. Chem Soc Rev 31(2):116–127
-
(2002)
Chem Soc Rev
, vol.31
, Issue.2
, pp. 116-127
-
-
Rurack, K1
Resch-Genger, U2
-
4
-
-
0004040064
-
Principles of fluorescence spectroscopy
-
4. JR Lakowicz 1999 Principles of fluorescence spectroscopy 2 Plenum New York Lakowicz JR (1999) Principles of fluorescence spectroscopy, 2nd edn. Plenum, New York
-
(1999)
-
-
Lakowicz, JR1
-
5
-
-
34547275903
-
Solvent and pH Effects on the fluorescence of 7-(Dimethylamino)-2-fluorenesulfonate
-
5. KP Kwanghee WP Joon DH Andrew 2007 Solvent and pH Effects on the fluorescence of 7-(Dimethylamino)-2-fluorenesulfonate J Fluoresc 17 4 361 369 10.1007/s10895-007-0193-1 Kwanghee KP, Joon WP, Andrew DH (2007) Solvent and pH Effects on the fluorescence of 7-(Dimethylamino)-2-fluorenesulfonate. J Fluoresc 17(4):361–369
-
(2007)
J Fluoresc
, vol.17
, Issue.4
, pp. 361-369
-
-
Kwanghee, KP1
Joon, WP2
Andrew, DH3
-
6
-
-
33847678433
-
Synthesis and fluorescence studies of some new fluorophores and their effect on hybridization of oligodeoxyribonucleotides
-
6. S Singh PK Singh 2007 Synthesis and fluorescence studies of some new fluorophores and their effect on hybridization of oligodeoxyribonucleotides J Fluoresc 17 2 139 148 17235674 10.1007/s10895-006-0151-3 1:CAS:528:DC%2BD2sXisV2htL0%3D Singh S, Singh PK (2007) Synthesis and fluorescence studies of some new fluorophores and their effect on hybridization of oligodeoxyribonucleotides. J Fluoresc 17(2):139–148
-
(2007)
J Fluoresc
, vol.17
, Issue.2
, pp. 139-148
-
-
Singh, S1
Singh, PK2
-
7
-
-
3543051290
-
Acridones and quinacridones: novel fluorophores for fluorescence lifetime studies
-
7. JA Smith RM West M Allen 2004 Acridones and quinacridones: novel fluorophores for fluorescence lifetime studies J Fluoresc 14 2 151 171 15615041 10.1023/B:JOFL.0000016287.56322.eb 1:CAS:528:DC%2BD2cXhtlWqsLc%3D Smith JA, West RM, Allen M (2004) Acridones and quinacridones: novel fluorophores for fluorescence lifetime studies. J Fluoresc 14(2):151–171
-
(2004)
J Fluoresc
, vol.14
, Issue.2
, pp. 151-171
-
-
Smith, JA1
West, RM2
Allen, M3
-
8
-
-
0035253874
-
Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines
-
8. C Almansa AF Arriba de FL Cavalcanti LA Gomez A Miralles M Merlos J Garcia-Rafanell J Forn 2001 Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a ]pyrimidines J Med Chem 44 3 350 361 11462976 10.1021/jm0009383 1:CAS:528:DC%2BD3MXms1Wg Almansa C, de Arriba AF, Cavalcanti FL, Gomez LA, Miralles A, Merlos M, Garcia-Rafanell J, Forn J (2001) Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a ]pyrimidines. J Med Chem 44(3):350–361
-
(2001)
J Med Chem
, vol.44
, Issue.3
, pp. 350-361
-
-
Almansa, C1
Arriba, AF2
Cavalcanti, FL3
Gomez, LA4
Miralles, A5
Merlos, M6
Garcia-Rafanell, J7
Forn, J8
-
9
-
-
8644228523
-
Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity
-
9. DR Compton SB Sheng KE Carlson NA Rebacz IY Lee BS Katzenellenbogen JA Katzenellenbogen 2004 Pyrazolo[1,5-a ]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity J Med Chem 47 24 5872 5893 15537344 10.1021/jm049631k 1:CAS:528:DC%2BD2cXos1WjsLo%3D Compton DR, Sheng SB, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA (2004) Pyrazolo[1,5-a ]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. J Med Chem 47(24):5872–5893
-
(2004)
J Med Chem
, vol.47
, Issue.24
, pp. 5872-5893
-
-
Compton, DR1
Sheng, SB2
Carlson, KE3
Rebacz, NA4
Lee, IY5
Katzenellenbogen, BS6
Katzenellenbogen, JA7
-
10
-
-
27144557568
-
A novel selective GABA(A) alpha 1 receptor agonist displaying sedative and anxiolytic-like properties in rodents
-
10. S Selleri F Bruni C Costagli A Costanzo G Guerrini G Ciciani P Gratteri F Besnard B Costa M Montali C Martini J Fohlin G Siena De PA Aiello 2005 A novel selective GABA(A) alpha 1 receptor agonist displaying sedative and anxiolytic-like properties in rodents J Med Chem 48 21 6756 6760 16220991 10.1021/jm058002n 1:CAS:528:DC%2BD2MXhtVeisr%2FK Selleri S, Bruni F, Costagli C, Costanzo A, Guerrini G, Ciciani G, Gratteri P, Besnard F, Costa B, Montali M, Martini C, Fohlin J, De Siena G, Aiello PA (2005) A novel selective GABA(A) alpha 1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. J Med Chem 48(21):6756–6760
-
(2005)
J Med Chem
, vol.48
, Issue.21
, pp. 6756-6760
-
-
Selleri, S1
Bruni, F2
Costagli, C3
Costanzo, A4
Guerrini, G5
Ciciani, G6
Gratteri, P7
Besnard, F8
Costa, B9
Montali, M10
Martini, C11
Fohlin, J12
Siena, G13
Aiello, PA14
-
11
-
-
0031895855
-
Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice
-
11. F Nishigaki S Tsujimoto N Yamamoto I Kawamura Y Naoe M Inami L Elizabeth T Manda K Shimomura 1998 Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice Anticancer Res 18 1A 139 144 9568068 Nishigaki F, Tsujimoto S, Yamamoto N, Kawamura I, Naoe Y, Inami M, Elizabeth L, Manda T, Shimomura K (1998) Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice. Anticancer Res 18(1A):139–144
-
(1998)
Anticancer Res
, vol.18
, Issue.1A
, pp. 139-144
-
-
Nishigaki, F1
Tsujimoto, S2
Yamamoto, N3
Kawamura, I4
Naoe, Y5
Inami, M6
Elizabeth, L7
Manda, T8
Shimomura, K9
-
12
-
-
4444225367
-
Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists
-
12. C Chen KM Wilcoxen CQ Huang YF Xie JR McCarthy TR Webb YF Zhu J Saunders XJ Liu TK Chen H Bozigian DE Grigoriadis 2004 Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a ]pyrimidine (NBI 30775/R121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists J Med Chem 47 19 4787 4798 15341493 10.1021/jm040058e 1:CAS:528:DC%2BD2cXmt12ksrs%3D Chen C, Wilcoxen KM, Huang CQ, Xie YF, McCarthy JR, Webb TR, Zhu YF, Saunders J, Liu XJ, Chen TK, Bozigian H, Grigoriadis DE (2004) Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylamino-pyrazolo[1,5-a ]pyrimidine (NBI 30775/R121919) and structure-activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. J Med Chem 47(19):4787–4798
-
(2004)
J Med Chem
, vol.47
, Issue.19
, pp. 4787-4798
-
-
Chen, C1
Wilcoxen, KM2
Huang, CQ3
Xie, YF4
McCarthy, JR5
Webb, TR6
Zhu, YF7
Saunders, J8
Liu, XJ9
Chen, TK10
Bozigian, H11
Grigoriadis, DE12
-
13
-
-
15444341737
-
New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol
-
13. J Bartroli E Turmo M Alguero E Boncompte ML Vericat L Conte J Ramis M Merlos J García-Rafanell J Forn 1998 New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol J Med Chem 41 11 1855 1868 9599236 10.1021/jm970726e 1:CAS:528:DyaK1cXis12qu7o%3D Bartroli J, Turmo E, Alguero M, Boncompte E, Vericat ML, Conte L, Ramis J, Merlos M, García-Rafanell J, Forn J (1998) New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol. J Med Chem 41(11):1855–1868
-
(1998)
J Med Chem
, vol.41
, Issue.11
, pp. 1855-1868
-
-
Bartroli, J1
Turmo, E2
Alguero, M3
Boncompte, E4
Vericat, ML5
Conte, L6
Ramis, J7
Merlos, M8
García-Rafanell, J9
Forn, J10
-
14
-
-
17744412817
-
Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics
-
14. ME Fraley RS Rubino WF Hoffman SR Hambaugh KL Arrington RW Hungate MT Bilodeau AJ Tebben RZ Rutledge RL Kendall RC McFall WR Huckle KE Coll KA Thomas 2002 Optimization of a pyrazolo[1,5-a ]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics Bioorg Med Chem Lett 12 24 3537 3541 12443771 10.1016/S0960-894X(02)00827-2 1:CAS:528:DC%2BD38XoslyrsL8%3D Fraley ME, Rubino RS, Hoffman WF, Hambaugh SR, Arrington KL, Hungate RW, Bilodeau MT, Tebben AJ, Rutledge RZ, Kendall RL, McFall RC, Huckle WR, Coll KE, Thomas KA (2002) Optimization of a pyrazolo[1,5-a ]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics. Bioorg Med Chem Lett 12(24):3537–3541
-
(2002)
Bioorg Med Chem Lett
, vol.12
, Issue.24
, pp. 3537-3541
-
-
Fraley, ME1
Rubino, RS2
Hoffman, WF3
Hambaugh, SR4
Arrington, KL5
Hungate, RW6
Bilodeau, MT7
Tebben, AJ8
Rutledge, RZ9
Kendall, RL10
McFall, RC11
Huckle, WR12
Coll, KE13
Thomas, KA14
-
15
-
-
33747435799
-
Skraup–Doebner–von Miller quinoline synthesis revisited: reversal of the regiochemistry for gamma-aryl-beta,gamma-unsaturated alpha-ketoesters
-
15. YC Wu L Liu HJ Li D Wang YJ Chen 2006 Skraup–Doebner–von Miller quinoline synthesis revisited: reversal of the regiochemistry for gamma-aryl-beta,gamma-unsaturated alpha-ketoesters J Org Chem 71 17 6592 6595 16901148 10.1021/jo060290n 1:CAS:528:DC%2BD28XmvFGjs7g%3D Wu YC, Liu L, Li HJ, Wang D, Chen YJ (2006) Skraup–Doebner–von Miller quinoline synthesis revisited: reversal of the regiochemistry for gamma-aryl-beta,gamma-unsaturated alpha-ketoesters. J Org Chem 71(17):6592–6595
-
(2006)
J Org Chem
, vol.71
, Issue.17
, pp. 6592-6595
-
-
Wu, YC1
Liu, L2
Li, HJ3
Wang, D4
Chen, YJ5
-
16
-
-
32244432737
-
3-(4-Methoxystyryl)-2H-1,4-benzoxazin-2-one
-
16. YC Wu HB Song L Liu D Wang YJ Chen 2005 3-(4-Methoxystyryl)-2 H-1,4-benzoxazin-2-one Acta Cryst E61 o1590 1:CAS:528:DC%2BD2MXkslChsL8%3D Wu YC, Song HB, Liu L, Wang D, Chen YJ (2005) 3-(4-Methoxystyryl)-2 H-1,4-benzoxazin-2-one. Acta Cryst E61:o1590
-
(2005)
Acta Cryst
, vol.E61
, pp. o1590
-
-
Wu, YC1
Song, HB2
Liu, L3
Wang, D4
Chen, YJ5
-
17
-
-
33645403442
-
Synthesis of trifluoromethyl-promoted functional pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-d] [1,2,3,5]tetrazine-4(3H)-ones
-
17. YC Wu YJ Chen HJ Li XM Zou FZ Hu HZ Yang 2006 Synthesis of trifluoromethyl-promoted functional pyrazolo[1,5-a ]pyrimidine and pyrazolo[5,1-d ] [1,2,3,5]tetrazine-4(3 H)-ones J Fluorine Chem 127 3 409 416 10.1016/j.jfluchem.2006.02.001 1:CAS:528:DC%2BD28XjtFantrs%3D Wu YC, Chen YJ, Li HJ, Zou XM, Hu FZ, Yang HZ (2006) Synthesis of trifluoromethyl-promoted functional pyrazolo[1,5-a ]pyrimidine and pyrazolo[5,1-d ] [1,2,3,5]tetrazine-4(3 H)-ones. J Fluorine Chem 127(3):409–416
-
(2006)
J Fluorine Chem
, vol.127
, Issue.3
, pp. 409-416
-
-
Wu, YC1
Chen, YJ2
Li, HJ3
Zou, XM4
Hu, FZ5
Yang, HZ6
-
18
-
-
34447509611
-
InCl3-catalyzed propargylation of indoles and phenols with propargylic acetates: application to the syntheses of benzofurans and naphthofurans
-
18. Z Liu L Liu Z Shafiq YC Wu D Wang YJ Chen 2007 InCl3-catalyzed propargylation of indoles and phenols with propargylic acetates: application to the syntheses of benzofurans and naphthofurans Synthesis 13 1961 1969 10.1055/s-2007-983735 Liu Z, Liu L, Shafiq Z, Wu YC, Wang D, Chen YJ (2007) InCl3-catalyzed propargylation of indoles and phenols with propargylic acetates: application to the syntheses of benzofurans and naphthofurans. Synthesis 13:1961–1969
-
(2007)
Synthesis
, vol.13
, pp. 1961-1969
-
-
Liu, Z1
Liu, L2
Shafiq, Z3
Wu, YC4
Wang, D5
Chen, YJ6
-
19
-
-
0010442092
-
Alpha-alkoxyallylation of activated carbonyl-compounds – a novel variant of the michael reaction
-
19. RM Coates SJ Hobbs 1984 Alpha-alkoxyallylation of activated carbonyl-compounds–a novel variant of the michael reaction J Org Chem 49 1 140 152 10.1021/jo00175a030 1:CAS:528:DyaL2cXjtlOktg%3D%3D Coates RM, Hobbs SJ (1984) Alpha-alkoxyallylation of activated carbonyl-compounds–a novel variant of the michael reaction. J Org Chem 49(1):140–152
-
(1984)
J Org Chem
, vol.49
, Issue.1
, pp. 140-152
-
-
Coates, RM1
Hobbs, SJ2
-
20
-
-
0024226858
-
Synthesis of new substituted pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a]1,3,5-triazines
-
20. W Ried S Aboulfetouh 1988 Synthesis of new substituted pyrazolo[1,5-a ]pyrimidines and pyrazolo[1,5-a ]1,3,5-triazines Tetrahedron 44 23 7155 7162 10.1016/S0040-4020(01)86083-X 1:CAS:528:DyaL1MXktl2htrY%3D Ried W, Aboulfetouh S (1988) Synthesis of new substituted pyrazolo[1,5-a ]pyrimidines and pyrazolo[1,5-a ]1,3,5-triazines. Tetrahedron 44(23):7155–7162
-
(1988)
Tetrahedron
, vol.44
, Issue.23
, pp. 7155-7162
-
-
Ried, W1
Aboulfetouh, S2
-
21
-
-
17144402188
-
Liquid-phase synthesis of combinatorial libraries based on 7-trifluoromethyl-substituted pyrazolo[1,5-a]pyrimidine scaffold
-
21. IL Dalinger IA Vatsadse SA Shevelev AV Ivachtchenko 2005 Liquid-phase synthesis of combinatorial libraries based on 7-trifluoromethyl-substituted pyrazolo[1,5-a ]pyrimidine scaffold J Comb Chem 7 2 236 245 15762751 10.1021/cc049855o 1:CAS:528:DC%2BD2MXhtFyqt70%3D Dalinger IL, Vatsadse IA, Shevelev SA, Ivachtchenko AV (2005) Liquid-phase synthesis of combinatorial libraries based on 7-trifluoromethyl-substituted pyrazolo[1,5-a ]pyrimidine scaffold. J Comb Chem 7(2):236–245
-
(2005)
J Comb Chem
, vol.7
, Issue.2
, pp. 236-245
-
-
Dalinger, IL1
Vatsadse, IA2
Shevelev, SA3
Ivachtchenko, AV4
-
22
-
-
34249935642
-
Pyrazolo[1,5-a]pyrimidines. Identification of the privileged structure and combinatorial synthesis of 3-(hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides
-
22. BT Gregg DO Tymoshenko DA Razzano MR Johnson 2007 Pyrazolo[1,5-a]pyrimidines. Identification of the privileged structure and combinatorial synthesis of 3-(hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides J Comb Chem 9 3 507 512 17439287 10.1021/cc0700039 1:CAS:528:DC%2BD2sXkt1Kntb0%3D and references therein Gregg BT, Tymoshenko DO, Razzano DA, Johnson MR (2007) Pyrazolo[1,5-a]pyrimidines. Identification of the privileged structure and combinatorial synthesis of 3-(hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides. J Comb Chem 9(3):507–512 and references therein
-
(2007)
J Comb Chem
, vol.9
, Issue.3
, pp. 507-512
-
-
Gregg, BT1
Tymoshenko, DO2
Razzano, DA3
Johnson, MR4
|