Absence of COSMC gene mutations in breast and colorectal carcinomas

APMIS

Volumn 116, Issue 2, 2008, Pages 154-155

  Yoo, Nam Jin ^a   Kim, Min Sung ^a   Lee, Sug Hyung ^a  

^a The Catholic University of Korea College of Medicine   (South Korea)

Author keywords

Breast cancer; Colon cancer; COSMC; Mutation

Indexed keywords

ANTIGEN; CHAPERONE; CORE 1BETA3 GAL T SPECIFIC MOLECULAR CHAPERONE PROTEIN; UNCLASSIFIED DRUG;

ANTIGEN EXPRESSION; AUTORADIOGRAPHY; BREAST CARCINOMA; CANCER TISSUE; CELL SURFACE; COLORECTAL CARCINOMA; COSMC GENE; GENE; GENE MUTATION; GENETIC ANALYSIS; HUMAN; LETTER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 40449132135     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2008.00965.x     Document Type: Letter

References (7)

1. 1 Gilboa E. The risk of autoimmunity associated with tumor immunotherapy. Nat Immunol 2001 ; 2: 789–92.
2. 2 Kudo T, Iwai T, Kubota T, Iwasaki H, Takayma Y, Hiruma T, et al. Molecular cloning and characterization of a novel UDP‐Gal:GalNAc(alpha) peptide beta 1,3‐galactosyltransferase (C1Gal‐T2), an enzyme synthesizing a core 1 structure of O‐glycan. J Biol Chem 2002 ; 277: 47724–31.
3. 3 Ju T, Cummings RD. A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3‐galactosyltransferase. Proc Natl Acad Sci U S A 2002 ; 99: 16613–8.
4. 4 Akamine S, Nakagoe T, Sawai T, Tsuji T, Tanaka K, Hidaka S, et al. Differences in prognosis of colorectal cancer patients based on the expression of sialyl Lewisa, sialyl Lewisx and sialyl Tn antigens in serum and tumor tissue. Anticancer Res 2004 ; 24: 2541–6.
5. 5 Tsuchiya A, Kanno M, Kawaguchi T, Endo Y, Zhang GJ, Ohtake T, et al. Prognostic relevance of Tn expression in breast cancer. Breast Cancer 1999 ; 6: 175–80.
6. 6 Schietinger A, Philip M, Yoshida BA, Azadi P, Liu H, Meredith SC, et al. A mutant chaperone converts a wild‐type protein into a tumor‐specific antigen. Science 2006 ; 314: 304–8.
7. 7 Lee SH, Shin MS, Park WS, Kim SY, Kim HS, Han JY, et al. Alterations of Fas (Apo‐1/CD95) gene in non‐small cell lung cancer. Oncogene 1999 ; 18: 3754–60.