Inhibitory effect of Agaricu blazei murill components on abnormal collagen fiber formation in human hepatocarcinoma cells

Bioscience, Biotechnology and Biochemistry

Volumn 72, Issue 2, 2008, Pages 621-623

  Sorimachi, Kenji ^a   Akimoto, Kazumi ^a   Koge, Takashi ^b  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b Nippon Gene Co Ltd   (Japan)

Author keywords

Agaricus blazei murill; Collagen fiber formation; Human hepatocarcinoma cells; Mycelia; Reverse transcription polymerase chain reaction (RT PCR)

Indexed keywords

CYTOLOGY; ETHANOL; PRECIPITATION (CHEMICAL); REACTION KINETICS;

AGARICUS BLAZEI MURILL; COLLAGEN FIBER FORMATION; HUMAN HEPATOCARCINOMA CELLS; MYCELIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION (RT-PCR);

COLLAGEN;

COLLAGEN; PLANT EXTRACT;

AGARICUS; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; LIVER TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

AGARICUS; CELL LINE, TUMOR; COLLAGEN; HUMANS; LIVER NEOPLASMS; PLANT EXTRACTS;

AGARICUS BLAZEI;

EID: 40449118737     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.70700     Document Type: Article

References (18)

1. Kawagishi, H., Inagaki, R., Kano, T., Mizuno, T., Shimura, K., Ito, H., Hagiwara, T., and Nakamura, T., Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies. Carbohydr. Res., 186, 267-273 (1989).
2. Itoh, H., Ito, H., Amano, H., and Noda, H., Inhibitory action of a (1 → 6)-β-D-glucan-protein complex (F-III-2-b) isolated from Agaricus blazei Murill ("Himematsutake") on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Jpn. J. Pharmacol., 66, 265-271 (1994).
3. Ito, H., Shimura, K., Itoh, H., and Kawade, M., Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) "Himematsutake" and its mechanisms in tumor bearing mice. Anticancer Res., 17, 277-284 (1997).
4. Ebina, T., and Fujimiya, Y., Antitumor effect of a peptide-glucan preparation extracted from Agaricus blazei in a double-grafted tumor system in mice. Biotherapy, 11, 259-265 (2001).
5. Ohno, N., Furukawa, M., Miura, N.-N., Adachi, Y., Motoi, M., and Yadomae, T., Antitumor β-glucan from the cultured body of Agaricus blazei. Biol. Pharm. Bull., 24, 820-828 (2001).
6. Fujimiya, Y., Suzuki, Y., Oshiman, K., Kobori, H., Moriguchi, K., Nakashima, H., Matsumoto, Y., Takahara, S., Ebina, T., and Katakura, R., Selection tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis. Cancer Immunol. Immunother., 46, 147-159 (1998).
7. Mizuno, M., Morimoto, M., Minato, K., and Tsuchida, H., Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice. Biosci. Biotechnol. Biochem., 62, 434-437 (2004).
8. Kaneko, R., Fontanari, L. M., Santos, S. A., Di Stasi, L. C., Rodrigues, E., and Eira, A. F., Effects of extracts from Brazilian sun-mushroom (Agaricus blazei) on the NK activity and lymphoproliferative responsiveness of Ehrlich tumor-bearing mice. Food Chem. Toxicol., 42, 909-916 (2004).
9. Ahn, W. S., Kim, D. J., Chae, G. T., Lee, J. M., Bae, S. M., Sin, J. I., Kim, Y. W., Namkoomg, S. E., and Lee, I. P., Natural killer cell activity and quality of life were improved by consumption of a mushroom extract, Agaricus blazei Murill, in gynecological cancer patients undergoing chemotherapy. Int. J. Gynecol. Cancer, 14, 589-594 (2004).
10. Sorimachi, K., Akimoto, K., Ikehara, Y., Inafuku, K., Okubo, A., and Yamazaki, S., Secretion of TNF-α, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murill fractions in vitro. Cell Struct. Funct., 26, 103-108 (2001).
11. Sorimachi, K., Ikehara, Y., Maezato, G., Okubo, A., Yamazaki, S., Akimoto, K., and Niwa, A., Inhibition by Agaricus blazei Murill fractions of cytophathic effect induced by Western Equine Encephalitis (WEE) virus on VERO cells in vitro. Biosci. Biothecnol. Biochem., 65, 1645-1647 (2001).
12. Osaki, Y., Kato, T., Yamamoto, K., Okubo, J., and Miyazaki, T., Antimutagenic and bacteriacidal substances in the fruiting body of a basidiomycete Agaricus blazei, Jun-17. Yakugaku Zasshi (in Japanese), 114, 342-350 (1994).
13. Menoli, R. C., Mantovani, M. S., Ribeiro, L. R., Speit, G., and Jordano, B. Q., Antimutagenic effects of the mushroom Agaricus blazei Murill extracts on V79 cells. Mutat. Res., 496, 5-13 (2001).
14. Kimura, Y., Kido, T., Takaku, T., Sumiyoshi, M., and Baba, K., Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions. Cancer Sci., 95, 758-764 (2004).
15. Sorimachi, K., Inhibition of collagen fiber formation by dextran sulfate in hepatic cells. Biomed. Res., 13, 75-79 (1992).
16. Nakamoto, T., Harasawa, H., Akimoto, K., Hirata, H., Kaneko, H., Kaneko, N., and Sorimachi, K., Effects of olmesartan medoxomil as an angiotensin II-receptor blocker in chronic hypoxic rats. Eur. J. Pharmacol., 528, 43-51 (2005).
17. Chano, T., Okabe, H., Saeki, Y., Ishizawa, M., Matsumoto, K., and Hukuda, S., Characterization of a newly established human chondrosarcoma cell line, CS-OKB. Virchows Arch., 432, 529-534 (1998).
18. Akimoto, K., Ikeda, M., and Sorimachi, K., Inhibitory effect of heparin on collagen fiber formation in hepatic cells. Cell Struct. Funct., 22, 533-538 (1997).