Acute insulin response to arginine in deceased donors predicts the outcome of human islet isolation

American Journal of Transplantation

Volumn 8, Issue 4, 2008, Pages 872-876

  Hubert, T ^a,d   Strecker, G ^b   Gmyr, V ^a,d   Arnalsteen, L ^a,b   Garrigue, D ^b   Ezzouaoui, R ^a,d   Caiazzo, R ^a,b   Dezfoulian, G ^b   Averland, B ^c   Vandewalle, B ^a,d   Vantyghem, M C ^b   Kerr Conte, J ^a,d   Pattou, F ^a,b,d  

^a INSERM   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c Agence de Biomédecine   (France)

^d UNIV LILLE   (France)

Author keywords

Donor evaluation; Donor screening; Donor selection; Insulin secretion; Islet isolation; Islet transplantation

Indexed keywords

ARGININE;

ADULT; ARTICLE; BODY MASS; CELL ISOLATION; CELL TRANSPLANTATION; CLINICAL ARTICLE; DONOR SELECTION; HUMAN; INSULIN RESPONSE; ORGAN DONOR; PANCREAS ISLET CELL; PREDICTION AND FORECASTING; PREDICTOR VARIABLE; PRIORITY JOURNAL; RISK REDUCTION; TREATMENT FAILURE; TREATMENT OUTCOME;

ARGININE; BRAIN DEATH; CADAVER; HUMANS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; PREDICTIVE VALUE OF TESTS; TISSUE AND ORGAN HARVESTING; TISSUE DONORS; TREATMENT OUTCOME;

EID: 40449110704     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2007.02131.x     Document Type: Article

References (26)

1. Shapiro AM, Ricordi C, Hering BJ et al. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006 355 : 1318 1330.
2. Nano R, Clissi B, Melzi R et al. Islet isolation for allotransplantation: Variables associated with successful islet yield and graft function. Diabetologia 2005 48 : 906 912.
3. O'Gorman D, Kin T, Murdoch T et al. The standardization of pancreatic donors for islet isolations. Transplantation 2005 80 : 801 806.
4. Hering BJ, Kandaswamy R, Ansite JD et al. Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes. JAMA 2005 293 : 830 835.
5. Hellman B. Actual distribution of the number and volume of the islets of Langerhans in different size classes in non-diabetic humans of varying ages. Nature 1959 184 (Suppl 19 1498 1499.
6. Hubert T, Jany T, Marcelli-Tourvieille S et al. Acute insulin response of donors is correlated with pancreatic islet isolation outcome in the pig. Diabetologia 2005 48 : 2069 2073.
7. Robertson RP. Estimation of beta cell mass by metabolic tests: Necessary, but how sufficient? Diabetes 2007 56 2420 2424.
8. Hubert T, Arnalsteen L, Jany T et al. Technique of pancreatic procurement for pancreatic islet isolation. Ann Chir 2005 130 : 384 390.
9. Hubert T, Gmyr V, Arnalsteen L et al. Influence of preservation solution on human islet isolation outcome. Transplantation 2007 83 : 270 276.
10. Vandewalle B, Douillard C, Kerr-Conte J et al. Human pancreatic islet quality control: Easy assessment of metabolic functions. Exp Clin Endocrinol Diabetes 1999 107 : 214 219.
11. Bertuzzi F, Ricordi C. Prediction of clinical outcome in islet allotransplantation. Diabetes Care 2007 30 : 410 417.
12. Nanji SA, Shapiro AM. Advances in pancreatic islet transplantation in humans. Diabetes Obes Metab 2006 8 : 15 25.
13. Collaborative Islet Transplant Registry (CITR) Annual Report (2006). Rockville, MD : CITR Coordinating Center The EMMES Corporation, 2006.
14. Korsgren O, Nilsson B, Berne C et al. Current status of clinical islet transplantation. Transplantation 2005 79 : 1289 1293.
15. Marcelli-Tourvieille S, Hubert T, Pattou F, Vantyghem MC. Acute insulin response (AIR): Review of protocols and clinical interest in islet transplantation. Diabetes Metab 2006 32 : 295 303.
16. Larsen MO, Rolin B, Sturis J et al. Measurements of insulin responses as predictive markers of pancreatic beta-cellmass in normal and beta-cell-reduced lean and obese Gottingen minipigs in vivo. Am J Physiol (Endocrinol Metab) 2006 290 : E670 677.
17. Teuscher AU, Kendall DM, Smets YF, Leone JP, Sutherland DE, Robertson RP. Successful islet autotransplantation in humans: Functional insulin secretory reserve as an estimate of surviving islet cell mass. Diabetes 1998 47 : 324 330.
18. Ryan EA, Lakey JR, Paty BW et al. Successful islet transplantation: Continued insulin reserve provides long-term glycemic control. Diabetes 2002 51 : 2148 2157.
19. Contreras JL, Eckstein C, Smyth CA et al. Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats. Diabetes 2003 52 : 2935 2942.
20. Brunicardi FC, Dyen Y, Brostrom L et al. The circulating hormonal milieu of the endocrine pancreas in healthy individuals, organ donors, and the isolated perfused human pancreas. Pancreas 2000 21 : 203 211.
21. Masson F, Thicoipe M, Gin H et al. The endocrine pancreas in brain-dead donors. A prospective study in 25 patients. Transplantation 1993 56 : 363 367.
22. Ferrannini E, Mari A. Beta cell function and its relation to insulin action in humans: A critical appraisal. Diabetologia 2004 47 : 943 956.
23. Matsumoto I, Sawada T, Nakano M et al. Improvement in islet yield from obese donors for human islet transplants. Transplantation 2004 78 : 880 885.
24. Proye C, Pattou F, Carnaille B, Paris JC, d'Herbomez M, Marchandise X. Intraoperative gastrin measurements during surgical management of patients with gastrinomas: Experience with 20 cases. World J Surg 1998 22 : 643 649.
25. Proye C, Pattou F, Carnaille B, Lefebvre J, Decoulx M, d'Herbomez M. Intraoperative insulin measurement during surgical management of insulinomas. World J Surg 1998 22 : 1218 1224.
26. Matsumoto S, Okitsu T, Iwanaga Y et al. Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet 2005 365 : 1642 1644.