Effects of Lactobacillus acidophilus 43121 and a mixture of Lactobacillus casei and Bifidobacterium longum on the serum cholesterol level and fecal sterol excretion in hypercholesterolemia-induced pigs

Bioscience, Biotechnology and Biochemistry

Volumn 72, Issue 2, 2008, Pages 595-600

  Park, Yoo Heon ^a,c   Kim, Jong Gun ^a   Shin, Young Won ^a   Kim, Hyung Soo ^b   Kim, Young Jun ^a   Chun, Taehoon ^a   Kim, Sae Hun ^a   Whang, Kwang Youn ^a  

^a Korea University   (South Korea)

^b Culture Systems Inc   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Cholesterol; Fecal sterol; Hypocholesterolemic effect; Lactic acid bacteria; Pig

Indexed keywords

CHOLESTEROL; HYDROXYLATION; LIVING SYSTEMS STUDIES; PROTEINS;

BIFIDOBACTERIUM LONGUM; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTOBACILLUS CASEI;

BACTERIA;

CHOLESTEROL; STEROL;

ANIMAL; ARTICLE; BIFIDOBACTERIUM; BLOOD; FECES; HYPERCHOLESTEROLEMIA; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SWINE;

ANIMALS; BIFIDOBACTERIUM; CHOLESTEROL; FECES; HYPERCHOLESTEROLEMIA; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; STEROLS; SWINE;

BACTERIA (MICROORGANISMS); BIFIDOBACTERIUM LONGUM; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS CASEI; SUIDAE;

EID: 40449083602     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.70581     Document Type: Article

References (25)

1. Kannel, W. B., Doyle, J. T., Ostfeld, A. M., Jenkins, C. D., Kuller, L., Podell, R. N., and Stamler, J., Optimal resources for primary prevention of atherosclerotic disease. Circulation, 70, 155A-205A (1984).
2. Levy, R. I., Cholesterol, lipoproteins and heart disease present status and future prospects. Clin. Chem., 27, 653-662 (1981).
3. Lipid Research Clinics Program, The lipid research clinics coronary primary prevention trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA, 251, 365-374 (1984).
4. De Smet, I., Van Hoorde, L., De Sayer, N., Vande Woestyne, M., and Verstraete, W., In vitro study of bile salt hydrolase (BSH) activity of BSH isogenic Lactobacillus plantarum 80 strains and estimation of cholesterol lowering through enhanced BSH activity. Microb. Ecol. Health Dis., 7, 315-329 (1994).
5. Keys, A., Serum cholesterol response to dietary cholesterol. Am. J. Clin. Nutr., 40, 351-359 (1984).
6. Miller, E. R., and Ullrey, D. E., The pig as a model for human nutrition. Annu. Rev. Nutr., 7, 361-382 (1987).
7. Jaspers, D. A., Massey, K. L., and Luedecke, O. L., Effects of consuming yogurts prepared with three culture strains on human serum lipoproteins. J. Food Sci., 49, 1178-1181 (1984).
8. Grunewald, K. K., Serum cholesterol levels in rats fed skim milk fermented by Lactobacillus acidophilus. J. Food Sci., 47, 2078-2079 (1982).
9. Hepner, G., Fried, R., St. Jeor., S., Fusetti, L., and Morin, R., Hypercholesterolemic effect of yogurt and milk. Am. J. Clin. Nutr., 32, 19-24 (1979).
10. De Smet, I., De Boever, P., and Verstraete, W., Cholesterol lowering in pigs through enhanced bacterial bile salt hydrolase activity. Br. J. Nutr., 79, 185-194 (1998).
11. Gilliland, S. E., Nelson, C. R., and Maxwell, C., Assimilation of cholesterol by Lactobacillus acidophilus. Appl. Environ. Microbiol., 49, 377-381 (1985).
12. Midtvedt, T., and Norman, A., Absorption of bile acids to intestinal microorganisms. Acta Pathol. Microbiol. Scand. B, 80, 202-210 (1972).
13. Hartman, R. E., and Holmlund, C. E., Binding of steroids by microorganisms. J. Bacteriol., 84, 1254-1259 (1962).
14. Bottazzi, V., Zacconi, C., Gonzaga, E., and Paladino, M., Absorption of cholesterol by intestinal lactic acid bacteria. Ann. Microbiol., 36, 1-5 (1986).
15. Noh, D. O., Kim, S. H., and Gilliland, S. E., Incorporation of cholesterol into the cellular membrane of Lactobacillus acidophilus ATCC 43121. J. Dairy Sci., 80, 3107-3113 (1997).
16. Corzo, G., and Gilliland, S. E., Bile salt hydrolase activity of three strains of Lactobacillus acidophilus. J. Dairy Sci., 82, 472-480 (1999).
17. th ed., NRC, Natl. Acad. Press, Washington, pp. 110-123 (1998).
18. "Guide for the Care and Use of Laboratory Animals," NRC, Natl. Acad. Press, Washington, pp. 8-48 (1996).
19. Grundy, S. M., Ahrens, Jr. E. H., and Miettinen, T. A., Quantitative isolation and gas-liquid chromatographic analysis of total fecal bile acids. J. Lipid Res., 6, 397-410 (1965).
20. Yen, G. C., and Chen, C. J., Effects of fractionation and the refining process of lard on cholesterol removal by β-cyclodextrin. J. Food Sci., 65, 622-624 (2000).
21. Gilliland, S. E., and Walker, D. K., Factors to consider when selecting a culture of Lactobacillus acidophilus as a dietary adjunct to produce a hypocholesterolemic effect in humans. J. Dairy Sci., 73, 905-911 (1990).
22. th, eds. Murray, P. K., Granner, D. K., Mayes, P. A., and Rodwell, V. W., Mc-Graw Hill Company, New York, pp. 219-230 (2003).
23. Kulkarni, M. S., Heidepriem, P. M., and Yielding, K. L., Production by lithocholic acid of DNA strand breaks in L1210 cells. Cancer Res., 40, 2666-2669 (1980).
24. de Rodas, B. Z., Gilliland, S. E., and Maxwell, C. B., Hypocholesterolemic action of Lactobacillus acidophilus ATCC 43121 and calcium in swine with hypercholesterolemia induced by diet. J. Dairy Sci., 79, 2121-2128 (1996).
25. Park, Y. H., Kim, J. G., Shin, Y. W., Kim, S. H., and Whang, K. Y., Effect of dietary inclusion of Lactobacillus acidophilus ATCC 43121 on cholesterol metabolism in rats. J. Microbiol. Biotechnol., 17, 655-662 (2007).