Optimal process synthesis for the production of multiple recombinant proteins

Biotechnology Progress

Volumn 20, Issue 4, 2004, Pages 1032-1043

  Iribarren, Oscar A ^a   Montagna, Jorge M ^a   Vecchietti, Aldo R ^a   Andrews, Barbara ^b   Asenjo, Juan A ^b   Pinto, José M ^c,d  

^a El INGAR Instituto de Desarollo y Diseno   (Argentina)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d POLYTECHNIC UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ESCHERICHIA COLI; MATHEMATICAL MODELS; OPTIMIZATION; PROTEINS; PURIFICATION; SYNTHESIS (CHEMICAL);

MULTIHOST PROTEINS; MULTIPRODUCTS;

BIOTECHNOLOGY;

RECOMBINANT PROTEIN;

ARTICLE; BIOSYNTHESIS; THEORETICAL MODEL;

MODELS, THEORETICAL; RECOMBINANT PROTEINS;

CRICETINAE; CRICETULUS GRISEUS; ESCHERICHIA COLI;

EID: 4043173342     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp034330+     Document Type: Article

References (21)

1. Asenjo, J. A.; Patrick, I. Protein Purification Applications: A Practical Approach; Harris, E., Angal, S., Eds.; IRL Press: Oxford, 1990; Chapter 1.6.
2. Asenjo, J. A.; Montagna, J. M.; Vecchietti, A. R.; Iribarren, O. A.; Pinto, J. M. Strategies for the Simultaneous Optimization of the Structure and the Process Variables of a Protein Production Plant. Comput. Chem. Eng. 2000, 24, 2277-2290.
3. Brooke, A.; Kendrick, D.; Meeraus, A. GAMS Release 2.25. User's Guide; The Scientific Press: San Francisco, 1992.
4. Bryant, C. H.; Rowe, R. C. Knowledge Discovery in Databases: Application to Chromatography. Trends Anal. Chem. 1998, 17, 18-24.
5. Datar, R. V.; Cartwright, T.; Rosen, C. G. Process Economics of Animal Cell and Bacterial Fermentations: A Case Study Analysis of Tissue Plasminogen Activator. Bio/Technology 1993, 11, 349-357.
6. Groep, M. E.; Gregory, M. E.; Kershenbaum, L. S.; Bogle, I. D. L. Performance Modeling and Simulation of Biochemical Process Sequences with Interacting Unit Operations. Biotechnol. Bioengng. 2000, 67 (3), 301-311.
7. Grossmann, I. E.; Sargent, R. W. H. Optimal Design of Multipurpose Chemical Plants. Ind. Eng. Chem. Process Des. Dev. 1979, 18, 343-348.
8. Knopf, F. C.; Okos, M. R.; Reklaitis, G. V. Optimal Design of Batch/Semicontinuous Processes. Ind. Eng. Chem. Process Des. Dev. 1982, 21, 79-86.
9. Kula, M. R.; Schütte, H. Purification of Proteins and the Disruption of Microbial Cells. Biotechnol. Prog. 1987, 3, 31-42.
10. Montagna, J. M.; Vecchietti, A. R.; Iribarren, O. A.; Pinto, J. M.; Asenjo, J. A. Optimal Design of Protein Production Plants with Time and Size Factor Process Models. Biotechnol. Prog. 2000, 16, 228-237.
11. Petrides, D.; Sapidou, E.; Calandranis, J. Computer Aided Process Analysis and Economic Evaluation for Biosynthetic Human Insulin Production - A Case Study. Biotechnol. Bioeng. 1995, 48, 529-541.
12. Pinto, J. M.; Montagna, J. M.; Vecchietti, A. R.; Iribarren, O. A.; Asenjo, J. A. Process Performance Models in the Optimization of Multiproduct Protein Production Plants. Biotechnol. Bioeng. 2001, 74, 451-465.
13. Ravemark, D. E.; Rippin, D. W. T. Optimal Design of Multiproduct Batch Plants. Comput. Chem. Eng. 1998, 22, 177-183.
14. Salomone, H. E.; Iribarren, O. A. Posynomial Modeling of Batch Plants. Comput. Chem. Eng. 1992, 16, 173-184.
15. Salomone, H. E.; Montagna, J. M.; Iribarren, O. A. Dynamic Simulations in the Design of Batch Processes. Comput. Chem. Eng. 1994, 18, 191-204.
16. Samsatli, N. J.; Shah, N. An Optimization Based Design Procedure for Biochemical Processes. Part I: Preliminary Design and Operation. Trans. Inst. Chem. Eng., Part C 1996a, 74, 221-231.
17. Samsatli, N. J.; Shah, N. An Optimization Based Design Procedure for Biochemical Processes. Part II: Detailed Scheduling. Trans. Inst. Chem. Eng., Part C 1996b, 74, 232-242.
18. Steffens, M. A.; Fraga, E. S.; Bogle, I. D. L. Synthesis of Bioprocesses using Physical Properties Data. Biotechnol. Bioeng. 2000a, 68, 218-230.
19. Steffens M. A.; Fraga, E. S.; Bogle, I. D. L. Synthesis of Purification Tags for Optimal Downstream Processing. Comput. Chem. Eng. 2000b, 24 (2), 717-720.
20. Vásquez-Alvarez, E.; Lienqueo, M. E.; Pinto, J. M. Optimal Synthesis of Protein Purification Processes. Biotechnol. Prog. 2001, 17, 685-696.
21. Viswanathan, J. V.; Grossmann, I. E. A Combined Penalty Function and Outer Approximation Method for MINLP Optimization. Comput. Chem. Eng. 1990, 14, 769-782.