New antithrombotics with an indazole structure

Archiv der Pharmazie

Volumn 337, Issue 6, 2004, Pages 311-316

  Yildiz, Ali Kemal ^a   Rehse, Klaus ^a   Stasch, Johannes Peter ^b   Bischoff, Erwin ^b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b BAYER AG   (Germany)

Author keywords

Antithrombotic properties; Indazole derivates; Phosphodiesterase 5; Soluble guanylate cylase; YC 1

Indexed keywords

ANTICOAGULANT AGENT; GUANYLATE CYCLASE; INDAZOLE DERIVATIVE; N (2 HYDROXYETHYLAMINOETHYL) 1 (2 FLUOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOETHYL) 1 (3 CHLOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOETHYL) 1 PHENYLMETHYL 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOPROPYL) 1 (2 CHLOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOPROPYL) 1 (2 FLUOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOPROPYL) 1 (3 CHLOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N (2 HYDROXYETHYLAMINOPROPYL) 1 PHENYLMETHYL 1H INDAZOLE 3 CARBOXAMIDE; N 3 AMINOPROPYL 1 (2 FLUOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 1 (2 CHLOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 1 (2 FLUOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 1 (3 CHLOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N [2 (DIMETHYLAMINO)ETHYL] 1 PHENYLMETHYL 1H INDAZOLE 3 CARBOXAMIDE; N [3 (DIMETHYLAMINO)PROPYL] 1 (2 FLUOROPHENYLMETHYL) 1H INDAZOLE 3 CARBOXAMIDE; N [3 (DIMETHYLAMINO)PROPYL] 1 PHENYLMETHYL 1H INDAZOLE 3 CARBOXAMIDE; N [3 (METHYLAMINO)PROPYL] 1 PHENYLMETHYL 1H INDAZOLE 3 CARBOXAMIDE; PHOSPHODIESTERASE; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; CGMP BINDING, CGMP SPECIFIC 3',5' CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; CYCLIC GMP PHOSPHODIESTERASE; FIBRINOLYTIC AGENT; PHOSPHODIESTERASE INHIBITOR;

ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE AGGREGATION INHIBITION; VEIN THROMBOSIS; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; ENZYME ACTIVATION; HUMAN; IN VITRO STUDY; METABOLISM; SYNTHESIS; THROMBOCYTE AGGREGATION; THROMBOSIS;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; ENZYME ACTIVATION; FIBRINOLYTIC AGENTS; GUANYLATE CYCLASE; HUMANS; INDAZOLES; PHOSPHODIESTERASE INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RATS; THROMBOSIS;

EID: 4043167622     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200300832     Document Type: Article

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