Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG

Vaccine

Volumn 22, Issue 25-26, 2004, Pages 3243-3255

  McKelvie, Nicola D ^a   Stratford, Richard ^a   Wu, Tao ^a   Bellaby, Trevor ^a   Aldred, Emma ^a   Hughes, Nicky J ^a   Chatfield, Steven N ^a   Pickard, Derek ^b   Hale, Christine ^b   Dougan, Gordon ^b   Khan, Shahid A ^a  

^a Microscience Limited   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Chromosomal expression; E. coli heat labile toxin; In vivo inducible expression; S. Typhimurium; Salmonella Pathogenicity Island 2; ssaG promoter

Indexed keywords

BACTERIAL DNA; BACTERIAL TOXIN; HUMORAL ANTIBODY; SALMONELLOSIS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; ESCHERICHIA COLI; EXPRESSION VECTOR; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNIZATION; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PATHOGENICITY ISLAND; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SALMONELLA ENTERICA; SALMONELLA PATHOGENICITY ISLAND 2; SALMONELLA TYPHIMURIUM; STATISTICAL SIGNIFICANCE; UPREGULATION;

ANIMALS; ANTIGENS, BACTERIAL; BASE SEQUENCE; CELL SURVIVAL; CELLS, CULTURED; CHROMOSOMES, BACTERIAL; CULTURE MEDIA; DNA PRIMERS; FLOW CYTOMETRY; GENES, BACTERIAL; GENES, REPORTER; HUMANS; IMMUNOGLOBULIN G; LAC OPERON; MACROPHAGES; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PLASMIDS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALMONELLA TYPHIMURIUM; SALMONELLA VACCINES; VACCINES, DNA;

EID: 4043154250     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.05.014     Document Type: Article

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