Functional properties of a recombinant chimeric plasminogen activator with platelet-targeted fibrinolytic and anticoagulant potential

Molecular Genetics and Metabolism

Volumn 82, Issue 4, 2004, Pages 304-311

  Zhang, Leiliang ^a   Wang, Jing ^a   Yu, Meimin ^a   Ru, Binggen ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Antithrombin activity; Decorsin; Hirudin; Platelet targeted

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CHIMERIC PROTEIN; FIBRINOLYTIC AGENT; HIRUDIN; RECOMBINANT PLASMINOGEN ACTIVATOR; THROMBIN INHIBITOR; UROKINASE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL INCLUSION; CONTROLLED STUDY; DILUTION; DRUG ACTIVITY; DRUG EFFECT; DRUG SYNTHESIS; ESCHERICHIA COLI; FIBRIN CLOT; GEL FILTRATION CHROMATOGRAPHY; HUMAN; ION EXCHANGE CHROMATOGRAPHY; MICHAELIS MENTEN KINETICS; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN TARGETING; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

ANTICOAGULANTS; BLOOD PLATELETS; FIBRINOLYTIC AGENTS; HUMANS; PLASMINOGEN ACTIVATORS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; RECOMBINANT FUSION PROTEINS; THROMBIN;

ESCHERICHIA COLI;

EID: 4043127547     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2004.05.008     Document Type: Article

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