Antioxidant and cytotoxic activities of Retama raetam subsp. gussonei

Phytotherapy Research

Volumn 18, Issue 7, 2004, Pages 585-587

  Conforti, F ^a   Statti, G ^a   Tundis, R ^a   Loizzo, M R ^a   Bonesi, M ^a   Menichini, F ^a   Houghton, P J ^b  

^a UNIVERSITY OF CALABRIA   (Italy)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antioxidant; Cytotoxicity; Liposomes; Retama raetam subsp. gussonei

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; BRAIN EXTRACT; LIPOSOME; PLANT EXTRACT; RADICAL; RETAMA RAETAM GUSSONEI EXTRACT; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BLEACHING; CANCER CELL CULTURE; CELL STRAIN COR L23; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; LARGE CELL CARCINOMA; LIPID PEROXIDATION; NONHUMAN; PLANT; PLANT LEAF; PLANT SEED; RETAMA RAETAM GUSSONEI;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTIOXIDANTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FABACEAE; HUMANS; LIPID PEROXIDATION; LIPOSOMES; PHYTOTHERAPY; PICRATES; PLANT EXTRACTS; PLANT LEAVES; SEEDS;

BOVINAE; RETAMA; RETAMA RAETAM;

EID: 4043101804     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1496     Document Type: Article

References (16)

1. Abdel Halim OB, Abdel Fattah H, Halim AF, Murakoshi I. 1997. Comparative chemical and biological studies of the alkaloidal content of Lygos species and varieties growing in Egypt. Acta Pharm Hung 67: 241-247.
2. Cassady JM, Baird WM, Chang CJ. 1990. Natural products as a source of potential cancer chemotherapeutic and chemopreventive agents. J Natural Products 53: 23-41.
3. Cavin A, Hostettmann K, Dyatmyko W, Potterat O. 1998. Antioxidant and Lipophilic Constituents of Tinospora crispa. Planta Medica 64: 393-396.
4. Chen ZY, Chan PT, Ho KY et al. 1996. Antioxidant activity of natural flavonoids is governed by number and location of their aromatic hydroxyl groups. Chem Phys Lipids 79: 157-163.
5. Fernandez J, Perez-Alvarez J, Fernandez-Lopez J. 1997. Thiobarbituric acid test for monitoring lipid oxidation in meat. Food Chem 59: 345.
6. Frankel E, Kanner J, Kinsella JE. 1993. Inhibition in vitro of oxidation of human low density lipoproteins by phenolic substances in wine. Lancet 341: 1-4.
7. Jacobi H, Hinrichsen M, Web D, Witte I. 1999. Induction of lipid peroxidation in human fibroblasts by the antioxidant propyl gallate in combination with copper (11). Toxicol Lett 110: 183-190.
8. Kassem M, Mosharrafa SA, Saleh NAM, Abdel-Wahab SM. 2000. Two new flavonoids from Retama raetam. Fitoterapia 71: 649-654.
9. Mangiapane H, Thompson J, Brown S, et al. 1992. The inhibition of LDL oxidation by naturally occurring flavonoids. Biochem Pharmacol 43: 445-452.
10. Mattocks AR. 1986. Chemistry and Toxicology of Pyrrolizidine Alkaloids. Academic Press: Orlando, FL.
11. Miranda CL, Stevens JF, Helmrich A, et al. 1999. Antiproliferative and Cytotoxic Effects of Prenylated Flavonoids from Hops (Humulus lupus) in Human Cancer Cell Lines. Food Chem Toxicol 37: 271-285.
12. Pignatti S. 1982. Flora D'Italia. Edagricole (ed): Bologna, Italy; 644.
13. Rubinstein LV, Shoemaker RH, Paull KD, et al. 1990. Comparison of in vitro anticancer-drug-screening data generated with a tretrazolium assay versus a protein assay against a diverse panel of human tumour cell lines. J National Cancer Inst 82: 1113-1118.
14. Skehan P, Storeng R, Scudiero D, et al. 1990. New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening. J National Cancer Inst 82: 1107-1112.
15. Tutin TG, Heywood VH, Burges NA, et al. 1968. Flora Europaea. Cambridge University Press: Cambridge; 101.
16. Verma AK, Johnson JA, Gould MN, Tanner MA. 1988. Inhibition of 7,12-dimethylbenz[a]anthracene- and N-nitros-p-methylurea-induced rat mammary cancer by the dietary flavonol, quercetin. Cancer Res 48: 5754-5758.