A software tool to assist business-process decision-making in the biopharmaceutical industry

Biotechnology Progress

Volumn 20, Issue 4, 2004, Pages 1096-1102

  Mustafa, Mustafa A ^a   Washbrook, John ^a   Ai, Chye Lim ^a   Zhou, Yuhong ^a   Titchener Hooker, Nigel J ^a   Morton, Philip ^b   Berezenko, Steve ^b   Farid, Suzanne S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Delta Biotechnology Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHY; COSTS; DECISION MAKING; DRUG PRODUCTS; ECONOMIC AND SOCIAL EFFECTS;

BIOPROCESSES; EXPANDED BED ABSORPTION (EBA);

BIOTECHNOLOGY;

ADSORPTION; ARTICLE; COMPUTER PROGRAM; DRUG INDUSTRY; ORGANIZATION AND MANAGEMENT; PHARMACEUTICS; THEORETICAL MODEL;

ADSORPTION; BIOPHARMACEUTICS; DRUG INDUSTRY; MODELS, THEORETICAL; SOFTWARE;

EID: 4043094058     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp034377v     Document Type: Article

References (12)

1. Pisano, G.; Wheelwright, S. C. High-tech R&D. Harv. Bus. Rev. 1995, Sept-Oct, 93-105.
2. Aldridge, S. Overcoming challenges in biomanufacturing. Gen. Eng. News 2003, 23, 14.
3. Sundberg, F. Coming to terms with compliance. Pharm. Technol. 2003, 15 (4), 39-41.
4. Karri, S.; Davies, E.; Titchener-Hooker, N. J.; Washbrook, J. Biopharmaceutical process development: Part III, a framework to assist decision making. Biopharm. 2001, 13 (9), 76-82.
5. Coopers & Lybrand. Pharmaceuticals: Creating value by transforming the cost base - Our approach; 1997.
6. Johansson, H. J.; Jägersten, C.; Shiloach, J. Large scale recovery and purification of periplasmic recombinant protein from E. coli using expanded bed adsorption chromatography followed by new ion exchange media. J. Biotechnol. 1996, 48, 9-14.
7. Beck, J.; Lewis-Sandy, D. Process economics modelling for decision-making during process development of therapeutic proteins. Proceedings of IBC's Production and Economics of Biopharmaceuticals, November 13-15, 2000, La Jolla, CA.
8. Walter, J.; Striffler, U.; Feuser, J. EBA technology vs conventional primary recovery: Technical feasibility and process economics. Proceedings of IBC's Production and Economics of Biopharmaceuticals, November 13-15, 2000, La Jolla, CA.
9. Larsson, L.; Walter, J. K. Strategies for the development of appropriate harvest methodologies: Technologies and economics. Proceedings of IBC's Production and Economics of Biopharmaceuticals, November 20-21, 2002, San Diego, CA.
10. Nothelfer, F.; Walter, J. K. A comparison of STREAMLINE expanded bed adsorption with the combined techniques of filtration and conventional fixed bed chromatography for the capture of an Fc-fusion protein from CHO cell culture. Amersham Biosciences (STREAMLINE expanded bed adsorption); Amersham Biosciences: 2002.
11. Farid, S.; Novais, J. L.; Karri, S.; Washbrook, J.; Titchener-Hooker, N. J. A tool for modelling strategic decisions in cell culture manufacturing. Biotechnol. Prog. 2000, 16 (5), 829-836.
12. Lang, H. J. Simplified approach to preliminary cost estimates. Chem. Eng. 1948, 55, 112-113.