Novel short-step synthesis of functionalized γ-phenyl-β- hydroxybutenoates and their cyclization to 4-hydroxycoumarins via the N-hydroxybenzotriazole methodology

Synthesis

Volumn , Issue 11, 2004, Pages 1775-1782

  Athanasellis, Giorgos ^a   Melagraki, Georgia ^a   Chatzidakis, Haralambos ^a   Afantitis, Antreas ^a   Detsi, Anastasia ^a   Igglessi Markopoulou, Olga ^a   Markopoulos, John ^b  

^a NATIONAL TECHNICAL UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

Acylations; Coumarins; Heterocycles; N hydroxybenzotriazole; Natural products; NMR spectroscopy

Indexed keywords

ACYLATION; ESTERS; NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPIC ANALYSIS;

C-ACYLATION COMPOUNDS; METHYLENE COMPOUNDS; SALICYLIC ACIDS; TITLE COMPOUNDS;

SYNTHESIS (CHEMICAL);

3 ACETYL 4 HYDROXY 6 METHYLCOUMARIN; 3 ACETYL 4 HYDROXY 8 METHOXYCOUMARIN; 3 ACETYL 4 HYDROXY 8 METHYLCOUMARIN; 3 ACETYL 4 HYDROXYCOUMARIN; 3 ACETYL 6 CHLORO 4 HYDROXYCOUMARIN; 3 BENZOYL 4 HYDROXYCOUMARIN; 3 CYANO 4 HYDROXY 8 METHOXYCOUMARIN; 3 CYANO 4 HYDROXY 8 METHYLCOUMARIN; 3 CYANO 4 HYDROXYCOUMARIN; 3 ETHOXYCARBONYL 4 HYDROXY 6 METHYLCOUMARIN; 3 ETHOXYCARBONYL 4 HYDROXY 8 METHOXYCOUMARIN; 3 ETHOXYCARBONYL 4 HYDROXY 8 METHYLCOUMARIN; 3 ETHOXYCARBONYL 4 HYDROXYCOUMARIN; 4 HYDROXY 3 METHOXYCARBONYLCOUMARIN; 4 HYDROXYCOUMARIN DERIVATIVE; 6 CHLORO 3 CYANO 4 HYDROXYCOUMARIN; 6 CHLORO 3 ETHOXYCARBONYL 4 HYDROXYCOUMARIN; BENZOTRIAZOLE DERIVATIVE; BUTYRIC ACID DERIVATIVE; ETHYL[(2 ACETOXY 3 METHOXYPHENYL)HYDROXYMETHYLIDENE]ETHOXYCARBONYLACETATE; ETHYL[(2 ACETOXY 3 METHYLPHENYL)HYDROXYMETHYLIDENE]ETHOXYCARBONYLACETATE; ETHYL[(2 ACETOXY 5 CHLOROPHENYL)HYDROXYMETHYLIDENE]ETHOXYCARBONYLACETATE; ETHYL[(2 ACETOXY 5 METHYLPHENYL)HYDROXYMETHYLIDENE]ETHOXYCARBONYLACETATE; ETHYL[(2 ACETOXYPHENYL)HYDROXYMETHYLIDENE]ACETYLACETATE; ETHYL[(2 ACETOXYPHENYL)HYDROXYMETHYLIDENE]BENZOYLACETATE; ETHYL[(2 ACETOXYPHENYL)HYDROXYMETHYLIDENE]ETHOXYCARBONYLACETATE; GAMMA PHENYL BETA HYDROXYBUTENOIC ACID DERIVATIVE; METHYL[(2 ACETOXYPHENYL)HYDROXYMETHYLIDENE]METHOXYCARBONYLACETATE; N HYDROXYBENZOTRIAZOLE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STOICHIOMETRY; STRUCTURE ANALYSIS;

EID: 4043066665     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829132     Document Type: Article

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