Regioselective aryl radical cyclization: Access to pyrimidine-annelated Spiro heterocycles through 5-exo ring closure

Synthesis

Volumn , Issue 11, 2004, Pages 1864-1868

  Majumdar, K C ^a   Mukhopadhyay, P P ^a  

^a UNIVERSITY OF KALYANI   (India)

Author keywords

5 exo trig; 6 chloromethyl 1,3 dimethyl uracil; Heterocyclic compounds; Organotin reagent; Radical cyclization; Spiro heterocycles

Indexed keywords

ACETONE; ALCOHOLS; POTASH; SYNTHESIS (CHEMICAL);

CYCLIZATION; REGIOSELECTIVE ARYL;

SODIUM COMPOUNDS;

1,3 DIMETHYLSPIRO(PYRIMIDINE 6,3' 2',3' TETRAHYDROBENZOFURAN) 2,4 DIONE DERIVATIVE; 1,3 DIMETHYLURACIL DERIVATIVE; 2 BROMONAPHTHOL; 2 BROMOPHENOL DERIVATIVE; 6 (2' BROMO 2' METHYLPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMO 3',5' DIMETHYLPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMO 4' METHYLPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMO 5' METHOXYPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMO 5' METHYLPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMOPHENEOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 (2' BROMOPHENOXYMETHYL) 1,3 DIMETHYL 1H PYRIMIDINE 2,4 DIONE; 6 CHLORO METHYL 1,3 DIMETHYLURACIL; ACETONE; AZOBISISOBUTYRONITRILE; BORANE DERIVATIVE; BROMINE DERIVATIVE; CYANOBOROHYDRIDE SODIUM; HETEROCYCLIC COMPOUND; NITRILE; POTASSIUM CARBONATE; PYRIMIDINE DERIVATIVE; SPIRO COMPOUND; TRIBUTYLTIN CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG STRUCTURE; REACTION ANALYSIS; RING CLOSING METATHESIS; STEREOCHEMISTRY;

EID: 4043060984     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829133     Document Type: Article

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