Effectiveness of corticosteroids in otitis media with effusion: An experimental study

Journal of Laryngology and Otology

Volumn 122, Issue 1, 2008, Pages 25-30

  Yaman, H ^a   Ozturk, K ^a   Uyar, Y ^a   Gurbilek, M ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Acoustic Impedence Tests; Corticosteroids; Interleukines; Otitis Media with Effusion; Tumour Necrosis Factor

Indexed keywords

INTERLEUKIN 1BETA; METHYLPREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; GLUCOCORTICOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY TUBE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; MIDDLE EAR EFFUSION; NONHUMAN; OTITIS MEDIA; RAT; TYMPANOMETRY; ACOUSTIC IMPEDANCE; ANIMAL; DISEASE MODEL; DOSE RESPONSE; IMMUNOLOGY; METABOLISM; PATHOLOGY; SECRETORY OTITIS MEDIA; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

ACOUSTIC IMPEDANCE TESTS; ANIMALS; ANTI-INFLAMMATORY AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; INTERLEUKIN-1BETA; MALE; METHYLPREDNISOLONE; OTITIS MEDIA WITH EFFUSION; RATS; RATS, SPRAGUE-DAWLEY; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 40349102195     PISSN: 00222151     EISSN: 17485460     Source Type: Journal    
DOI: 10.1017/S0022215107007724     Document Type: Article

References (15)

1. Hebda PA, Piltcher OB, Swarts JD, Alper CM, Zeevi A, Doyle WJ. Cytokine profiles in a rat model of otitis media with effusion caused by eustachian tube obstruction with and without Streptococcus pneumoniae infection. Laryngoscope 2002;112:1657-62
2. Butler CC, van Der Voort JH. Steroids for otitis media with effusion: a systematic review. Arch Pediatr Adolesc Med 2001;155:641-7
3. Bluestone CD. Studies in otitis media: Children's Hospital of Pittsburgh - University of Pittsburgh progress report - 2004. Laryngoscope 2004;114:1-26
4. Yetiser S, Satar B, Gumusgun A, Unal F, Ozkaptan Y. Tumor necrosis factor-alpha and interleukin-1beta levels in recurrent and persistent otitis media with effusion. Otolaryngol Head Neck Surg 2002;126:417-22
5. Keles B, Ozturk K, Gunel E, Arbag H, Ozer B. Pharyngeal reflux in children with chronic otitis media with effusion. Acta Otolaryngol 2004;124:1178-81
6. Tada N, Furukawa M, OguraM, Arai S, Adachi Y, Ikehara S et al. Experimental otitis media with effusion induced by leukotriene D4. Auris Nasus Larynx 2002;29:127-32
7. McCormick DP, Saeed K, Uchida T, Baldwin CD, Deskin R, Lett-Brown MA et al. Middle ear fluid histamine and leukotriene B4 in acute otitis media: effect of antihistamine or corticosteroid treatment. Int J Pediatr Otorhinolaryngol 2003;67:221-30
8. Macknin ML, Jones PK. Oral dexamethasone for treatment of persistent middle ear effusion. Pediatrics 1985;75:329-35
9. Rosenfeld RM, Mandel EM, Bluestone CD. Systemic steroids for otitis media with effusion in children. Arch Otolaryngol Head Neck Surg 1991;117:984-9
10. Russell JD, Giles SJ. Persistent otitis media with effusion: a new experimental model. Laryngoscope 1998;108:1181-4
11. Lambert PR. Oral steroid therapy for chronic middle ear perfusion: a double-blind crossover study. Otolaryngol Head Neck Surg 1986;95:193-9
12. Berman S, Casselbrant ML, Chonmaitree T, Giebink GS, Grote JJ, Ingvarsson LB et al. Recent advances in otitis media. 9. Treatment, complications, and sequelae. Ann Otol Rhinol Laryngol Suppl 2002;188:102-24
13. Podoshin L, Fradis M, Ben-David Y, Faraggi D. The efficacy of oral steroids in the treatment of persistent otitis media with effusion. Arch Otolaryngol Head Neck Surg 1990;116:1404-6
14. Schwartz RH, Puglese J, Schwartz DM. Use of a short course of prednisone for treating middle ear effusion: a double-blind crossover study. Ann Otol Rhinol Laryngol 1980;89:296-300
15. Persico M, Podoshin L, Fradis M. Otitis media with effusion: a steroid and antibiotic therapeutic trial before surgery. Ann Otol Rhinol Laryngol 1978;87:191-6