In vitro blood flow in a rectangular PDMS microchannel: Experimental observations using a confocal micro-PIV system

Biomedical Microdevices

Volumn 10, Issue 2, 2008, Pages 153-167

  Lima, Rui ^a,b   Wada, Shigeo ^c   Tanaka, Shuji ^a   Takeda, Motohiro ^d   Ishikawa, Takuji ^a   Tsubota, Ken Ichi ^a   Imai, Yohsuke ^a   Yamaguchi, Takami ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b INSTITUTO POLITÉCNICO DE BRAGANÇA   (Portugal)

^c OSAKA UNIVERSITY   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Confocal micro PIV; Mesoscopic blood flow; Microcirculation; PDMS microchannel; Red blood cells

Indexed keywords

BLOOD; FLOW PATTERNS; FLOW RATE; MATHEMATICAL MODELS; MICROCIRCULATION; POLYDIMETHYLSILOXANE; VELOCITY MEASUREMENT;

BLOOD FLOW; MICROPARTICLE IMAGE VELOCIMETRY; OPTICAL SECTIONING;

MICROCHANNELS;

DIMETICONE; SODIUM CHLORIDE;

ARTICLE; BIOMEDICINE; BIOPHYSICS; BLOOD SAMPLING; CELL SUSPENSION; CONFOCAL MICROPARTICLE IMAGE VELOCIMETRY; CONTROLLED STUDY; ERYTHROCYTE; FLOW RATE; HEMATOCRIT; HUMAN; HUMAN CELL; IN VITRO STUDY; MATHEMATICAL COMPUTING; MICROCIRCULATION; MICROFLUIDIC ANALYSIS; PREDICTION; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING;

BLOOD FLOW VELOCITY; DIMETHYLPOLYSILOXANES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY, CONFOCAL; NYLONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 40349096097     PISSN: 13872176     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10544-007-9121-z     Document Type: Article

References (70)

1. R. Adrian, Annu. Rev. Fluid Mech. 23, 261-304 (1991)
2. C. Alonso, A. Pries, O. Kiesslich, D. Lerche, P. Gaehtgens, Am. J. Physiol. 268(1 Pt 2), H25-H32 (1995)
3. M. Baker, H. Wayland, Microvasc. Res. 7, 131-143 (1974)
4. D. Beebe, G. Mensing, G. Walker, Annu. Rev. Biomed. Eng. 4, 261-286 (2002)
5. L. Bitsch, L. Olesen, C. Westergaard, H. Bruus, H. Klank, J. Kutter, Exp. Fluids 39, 505-511 (2005)
6. J. Borenstein, H. Terai, K. King, E. Weinberg, M. Kaazempur-Mofrad, J. Vacanti, Biomedical Microdevices 4(3), 167-175 (2002)
7. G. Born, A. Melling, J. Whitelaw, Biorheology 15, 163-172 (1978)
8. T. Brown, J. Biomech. 33, 3-14 (2000)
9. H. Bruus, Theoretical microfluidics (MIC, Technical University of Denmark, Denmark, 2004)
10. G. Bugliarello, J. Hayden, Trans. Soc. Rheol. 7, 209-230 (1963)
11. C. Caro, T. Pedley, R. Schroter, W. Seed, The mechanics of the circulation (Oxford University Press, 1978)
12. W. Chang, D. Akin, M. Sedlak, M. Ladisch, R. Bashir, Biomedical Microdevices 5(4), 281-290 (2003)
13. S. Chien, S. Usami, R. Skalak, Blood flow in small tubes Handbook of Physiology - The cardiovascular system IV (1984) 217-249
14. T. Cochrane, J. Earnshaw, A. Love, Med. Biol. Eng. Comput. 19, 589-596 (1981)
15. C. Duffy, J. McDonald, O. Schueller, G. Whitesides, Anal. Chem. 70, 4974-4984 (1998)
16. S. Einav, R. Berman, P. Fuhro, P. DiGiovanni, S. Fine, J. Fridman, Biorheology 12, 207-210 (1975)
17. R. Fahraeus, T. Lindqvist, Am. J. Physiol. 96, 562-568 (1931)
18. M. Faivre, M. Abkarian, K. Bickraj, H. Stone, Biorheology 43, 147-159 (2006)
19. T. Fujii, Microelectron. Eng. 61-62, 907-914 (2002)
20. P. Gaehtgens, Biorheology 24, 367-376 (1987)
21. P. Gaehtgens, H. Meiselman, H. Wayland, Microvasc. Res. 2, 13-23 (1970)
22. S. Gifford, M. Frank, J. Derganc, C. Gabel, R. Austin, T. Yoshida, W. Bitensky, Biophys. J. 84, 623-633 (2003)
23. H. Goldsmith, V. Turitto, Tromb. Haemost. 55, 415-435 (1986)
24. H. Golster, M. Linden, S. Bertuglia, A. Colantuoni, G. Nilsson, F. Sjoberg, Microvasc. Res. 58, 62-73 (1999)
25. R. Gomez, R. Bashir, A. Sarikaya, M. Ladish, J. Sturgis, J. Robison, T. Geng, A. Bhunia, H. Apple, S. Wereley, Biomedical Microdevices 3(3), 201-209 (2001)
26. G. Holzapfel, G. Sommer, C. Gasser, P. Regitnig, Am. J. Physiol Heart Circ. Physiol. 289, H2048-H2058 (2005)
27. H. Kaji, T. Kawashima, M. Nishizawa, Langmuir 22, 10784-10787 (2006)
28. G.B. Kim, S.J. Lee, Exp Fluids 41, 195-200 (2006)
29. H. Kinoshita, M. Oshima, S. Kaneda, T. Fujii, Proceedings of the 9thICMSCLS (Boston, Massachusetts, USA, 2005)
30. A. Koutsiaris, D. Mathioulakis, S. Tsangaris, Meas. Sci. Technol. 10, 1037-1046 (1999)
31. R. Lima, Analysis of the blood flow behavior through microchannels by confocal micro-PIV/PTV system, Doctoral thesis (Tohoku University, Japan, 2007)
32. R. Lima, S. Wada, K. Tsubota, T. Yamaguchi, Proceedings of the 3rd IASTED ICB - BioMech (Benidorm, Spain, 485, 2005)
33. R. Lima, S. Wada, K. Tsubota, T. Yamaguchi, Meas. Sci. Technol. 17, 797-808 (2006)
34. R. Lima, S. Wada, M. Takeda, K. Tsubota, T. Yamaguchi, J. Biomech. 40, 2752-2757 (2007)
35. N. Maeda, Jpn. J. Physiol 46, 1-14 (1996)
36. A. Mata, A. Fleischman, S. Roy, Biomedical Microdevices 7(4), 281-293 (2005)
37. J. McDonald, G. Whitesides, Acc. Chem. Res 35(7), 491-499 (2002)
38. G. Mchedlishvili, N. Maeda, Jpn. J. Physiol 51, 19-30 (2001)
39. C. Meinhart, S. Wereley, J. Santiago, J. Fluids Eng 122, 285-289 (2000)
40. G. Minas, J. Martins, J. Ribeiro, R. Wolffenbuttel, J. Correia, Sens. Actuators 110, 33-38 (2004)
41. J. Moger, S. Matcher, C. Winlove, A. Shore, J. Biomed. Opt. 9(5), 982-994 (2004)
42. N. Mortensen, F. Okkels, H. Bruus, Phys. Rev. E 71, 1-4 (2005)
43. A. Nakano, Y. Sugii, M. Minamiyama, H. Niimi, Clin. Hemorheol. Microcirc. 29, 445-455 (2003)
44. N. Nguyen, S. Wereley, Fundamentals and applications of microfluidics (Artech House, Inc., Norwood, MA, 2002)
45. J. Park, K. Kihm, Opt. Lasers Eng. 44, 208-223 (2006)
46. J. Park, C. Choi, K. Kihm, Exp. Fluids 37, 105-119 (2004)
47. A. Parthasarathi, S. Japee, R. Pittman, Ann Biomed. Eng. 27, 313-325 (1999)
48. A. Pries, T. Secomb, Clin. Hemorheol. Microcirc. 29, 143-148 (2003)
49. A. Pries, T. Secomb, T. Gessner, M. Sperandio, J. Gross, P. Gaehtgens, Circ. Res. 75, 904-915 (1994)
50. M. Raffel, C. Willert, J. Kompenhans, Particle image velocimetry: A practical guide (Springer, Germany, 1998)
51. Rika nenpyo, Chronological scientific tables, (National Astronomical Observatory), Maruzen Co., Japan, 1996
52. J. Santiago, S. Wereley, C. Meinhart, D. Beebe, R. Adrian, Exp Fluids 25, 316-319 (1998)
53. T. Secomb, Symp. Soc. Exp. Biol. vol 49 (London, UK, 1995), pp. 305-321
54. S. Shevkoplyas, S. Gifford, T. Yoshida, M. Bitensky, Microvasc. Res. 65, 132-136 (2003)
55. M. Shin, K. Matsuda, O. Ishii, H. Terai, M. Kaazempur-Mofrad, J. Borenstein, M. Detmar, J. Vacanti, Biomedical Microdevices 6 (4), 269-278 (2004)
56. H. Steiger, R. Aaslid, S. Keller, H. Reulen, Heart Vessels 5(1), 41-46 (1989)
57. N. Sutton, M. Tracey, I. Johnston, R. Greenaway, M. Rampling, Microvasc. Res. 53, 272-281 (1997)
58. Y. Suzuki, N. Tateishi, M. Soutani, N. Maeda, Microcirculation 3, 49-57 (1996)
59. P. Tabeling, Proceedings of the 14th Australasian Fluid Mechanics Conference (Adelaide, Australia, 2001)
60. S. Takayama, J. McDonald, E. Ostuni, M. Liang, P. Kenis, F. Ismagilov, G. Whitesides, Patterning cells and their environments using multiple laminar fluid flows in capillary networks Proc. Natl. Acad. Sci. 96, 5545-5548 (1999)
61. T. Tanaani, S. Otsuki, N. Tomosada, Y. Kosugi, M. Shimizu, H. Ishida, Appl. Opt. 41(22), 4704-4708 (2002)
62. G. Tangelder, D. Slaaf, M. Muijtjens, T. Arts, M. Egbrink, R. Reneman, Circ. Res. 59, 505-514 (1986)
63. T. Thorsen, S. Maerkl, S. Quake, Science 298, 580-584 (2002)
64. M. Toner, D. Irimia, Annu. Rev. Biomed. Eng. 7, 77-103 (2005)
65. K. Tsukada, H. Minamitami, E. Sekizuka, C. Oshio, Physiol. Meas. 21 (4), 459-471 (2000)
66. W. Uijttewaal, E. Nijhof, R. Heethaar, J. Biomech. 27, 35-42 (1994)
67. M. Unger, H. Chou, T. Thorsen, A. Scherer, S. Quake, Science 288, 113-116 (2000)
68. P. Vennemann, K. Kiger, R. Lindken, B. Groenendijk, S. Stekelenburg-de Vos, T. Hagen, N. Ursem, R. Poelmann, J. Westerweel, B. Hierk, J. Biomech. 39, 1191-1200 (2006)
69. S. Wilhelm, B. Grobler, M. Gluch, H. Heinz, Confocal laser scanning microscopy: Principles (Carl Zeiss, Germany, 2003)
70. C. Willert, M. Raffel, J. Kompenhans, B. Stasicki, C. Kahler, Flow Meas. Instrum. 7, 247-256 (1996)