Effects of anonaine on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells

Molecules

Volumn 13, Issue 2, 2008, Pages 475-487

  Jae, Joon Lee ^a   Chun, Mei Jin ^a   Young, Kyoon Kim ^b   Shi, Yong Ryu ^c   Sung, Cil Lim ^a   Myung, Koo Lee ^a  

^a Chungbuk National University   (South Korea)

^b Kookmin University   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Anonaine; Dopamine biosynthesis; L DOPA induced cytotoxicity; PC12 cells

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; ANONAINE; APORPHINE DERIVATIVE; AROMATIC LEVO AMINO ACID DECARBOXYLASE; CALCIUM; CYCLIC AMP; DOPAMINE; ISOQUINOLINE DERIVATIVE; LEVODOPA; LIRIODENINE; MESSENGER RNA; TYROSINE 3 MONOOXYGENASE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL DEATH; CELL STRAIN; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RAT; TIME;

ANIMALS; APORPHINES; AROMATIC-L-AMINO-ACID DECARBOXYLASES; CALCIUM; CELL DEATH; CYCLIC AMP; DIOXOLES; DOPAMINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; ISOQUINOLINES; LEVODOPA; PC12 CELLS; RATS; RNA, MESSENGER; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 40349093060     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules13020475     Document Type: Article

References (36)

1. Martinez, L.A.; Rios, J.L.; Paya, M.; Alcaraz, M.J. Inhibition of nonenzymic lipid peroxidation by benzylisoquinoline alkaloids. Free Rad. Biol. Med. 1992, 12, 287-292.
2. Paulo, M. de Q.; Barbosa-Fiho, J.M.; Lima, E.O.; Maia, R.F.; Barbosa, R. de C.; Kaplan, M.A. Antimicrobial activity of benzylisoquinoline alkaloids from annona salzmanii D.C. J. Ethnopharmacol. 1992, 36, 39-41.
3. Protais, P.; Arbaoui, J.; Bakkali, E.H.; Bermejo, A.; Cortes, D. Effects of various isoquinoline alkaloids on in vitro 3H-dopamine uptake by rat striatal synaptosomes. J. Nat. Prod. 1995, 58, 1475-1484.
4. Kim, K.S.; Park, D.H.; Wessel, T.C.; Song, B.; Wagner, J.A.; Joh, T.H. A dual role for the cAMP-dependent protein kinase in tyrosine hydroxylase gene expression. Proc. Natl. Acad. Sci. USA 1993, 90, 3471-3475.
5. Dunkley, P.R.; Cote, A.; Harrison, S.M.; Herd, L.; Hall, A.; Powis, D.A. Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells. Biochem. Pharmacol. 1996, 51, 239-245.
6. Young, E.A.; Duchemin A.-M.; Neff, N.H.; Hadjiconstantinou, M. Parallel modulation of striatal dopamine synthetic enzymes by second messenger pathways. Eur. J. Pharmacol. 1998, 357, 15-23.
7. Marsden, C.D. Parkinson's disease. J. Neurol. Neurosurg. Ps. 1994, 57, 672-681.
8. Ziv, I.; Zilkha-Falb, R.; Offen, D.; Shirvan, A.; Barzilai, A.; Melamed, E. Levodopa induces apoptosis in cultured neuronal cells: a possible accelerator of nigrostriatal degeneration in Parkinson's disease? Mov. Disord. 1997, 12, 17-23.
9. Basma, A.N.; Morris, E.J.; Nicklas, W.J.; Geller, H.M. L-DOPA cytotoxicity to PC12 cells in culture is via its antoxidation. J. Neurochem. 1995, 64, 825-832.
10. Shin, J.S.; Kim, K.T.; Lee, M.K. Inhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells. Neurosci. Lett. 1998, 244, 161-164.
11. Jin, C.H.; Lee, J.J.; Yang, Y.J.; Kim, Y.M.; Kim, Y.K.; Ryu, S.Y.; Lee, M.K. Liriodenine inhibits dopamine biosynthesis and L-DOPA-induced dopamine content in PC12 cells. Arch. Pharm. Res. 2007, 30, 984-990.
12. Cassels, B.K.; Asencio, M.; Conget, P.; Speisky, H.; Videla, L.A.; Lissi, E.A. Structure-antioxidative activity relationships in benzylisoquinoline alkaloids. Pharmacol. Res. 1995, 31, 103-107.
13. Asencio, M.; Delaquerriere, B.; Cassels, B.K.; Speisky, H.; Comoy, E.; Protais, P. Biochemical and behavioral effects of boldine and glaucine on dopamine systems. Pharmacol. Biochem. Behav. 1999, 62, 7-13.
14. Loghin, F.; Chagraoui, A.; Asencio, M.; Comoy, E.; Speisky, H.; Cassels, B.; Protais, P. Effects of some antioxidative aporphine derivatives on striatal dopaminergic transmission and on MPTP-induced striatal dopamine depletion in B6CBA mice. Pharmacol. Sci. 2003, 18, 133-140.
15. Tischler, A.S.; Perlman, R.L.; Morse, G.M.; Sheard, B.E. Glucocorticoids increase catecholamine synthesis and storage in PC12 cells pheochromocytoma cell culture. J. Neurochem. 1983, 40, 364-370.
16. Byrd, J.C.; Hadjiconstantinou, M.; Cavalla, D. Epinephrine synthesis in the PC12 pheochromocytoma cell line. Eur. J. Pharmacol. 1986, 127, 139-142.
17. Lee, J.J.; Kim, Y.M.; Yin, S.Y.; Park, H.D.; Kang, M.H.; Hong, J.T.; Lee, M.K. Aggravation of L-DOPA-induced neurotoxicity by tetrahydropapaveroline in PC12 cells. Biochem. Pharmacol. 2003, 66, 1787-1795.
18. Shin, J.S.; Yun-Choi, H.S.; Kim, E.I.; Lee, M.K. Inhibitory effects of higenamine on dopamine content in PC12 cells. Planta Med. 1999, 65, 452-455.
19. Shin, J.S.; Kim, E.I.; Kai, M.; Lee, M.K. Inhibition of dopamine biosynthesis by protoberberine alkaloids in PC12 cells. Neurochem. Res. 2000, 25, 363-368.
20. Shin, J.S.; Lee, J.J.; Kim, Y.; Lee, C.K.; Yun, Y.P.; Lee, M.K. Inhibitory effects of ethaverine, a homologue of papaverine, on dopamine content in PC12 cells. Biol. Pharm. Bull. 2001, 24, 103-105.
21. Yin, S.Y.; Kim, Y.M.; Lee, J.J.; Jin, C.M.; Yang, Y.J.; Ma, J.J.; Kang, M.H.; Kai, M.; Lee, M.K. Enantio-selective inhibition of (1R,9S)- and (1S,9R)-β-hydrastines on dopamine biosynthesis in PC12 cells. Neuropharmacol. 2004, 47, 1045-1052.
22. Kim, Y.M.; Kim, M.N.; Lee, J.J.; Lee, M.K. Inhibition of dopamine biosynthesis by tetrahydropapaveroline. Neurosci. Lett. 2005, 386, 1-4.
23. Lee, M.K.; Zhang, Y.H. Inhibition of tyrosine hydroxylase by berberine. Med. Sci. Res. 1996, 24, 561-562.
24. Lee, M.K.; Zhang, Y.H.; Shin, J.S.; Lee, S.S. Inhibition of tyrosine hydroxylase by hydrastine. Med. Sci. Res. 1997, 25, 619-620.
25. Zhang, Y.H.; Shin, J.S.; Lee, S.S.; Kim, S.H.; Lee, M.K. Inhibition of tyrosine hydroxylase by bulbocapnine. Planta Med. 1997, 63, 362-363.
26. Cho, S.; Neff, N.H.; Hadjiconstantinou, M. Regulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase by dopaminergic drugs. Eur. J. Pharmacol. 1997, 323, 149-157.
27. Yin, S.Y.; Lee, J.J.; Kim, Y.M.; Jin, C.M.; Yang, Y.J.; Kang, M.H.; Kai, M.; Lee, M.K. Effects of (1R,9S)-β-hydrastine on L-DOPA-induced cytotoxicity in PC12 cells. Eur. J. Pharmacol. 2004, 488, 71-77.
28. Bannach, R.; Valenzuela, A.; Cassels, B.K.; Nunez-Vergara, L.J.; Speisky, H. Cytoprotective and antioxidant effects of boldine on tert-butyl hydroperoxide-induced damage to isolated hepatocytes. Cell. Biol. Toxicol. 1996, 12, 89-100.
29. Youn, Y.C.; Kwon, O.S.; Han, E.S.; Song, J.H.; Shin, Y.K.; Lee, C.S. Protective effect of boldine on dopamine-induced membrane permeability transition in brain mitochondria and viability loss in PC12 cells. Biochem. Pharmacol. 2002, 63, 495-505.
30. Woo, S.H.; Sun, N.J.; Cassady, J.M.; Snapka, R.M. Topoisomerase II inhibition by aporphine alkaloids. Biochem. Pharmacol. 1999, 57, 1141-1145.
31. Kim, Y.K.; Ryu, S.Y. Cytotoxic components from stem bark of Magnolia ovobata. Planta Med. 1999, 65, 291-292.
32. Nagatsu, T.; Oka, K.; Kato, K. Highly sensitive assay for tyrosine hydroxylase activity by high-performance liquid chromatography. J. Chromatogr. 1979, 163, 247-252.
33. Lee, M.K.; Nohta, H.; Ohkura, Y. Occurrence of aromatic L-amino acid decarboxylase in human plasma and its assay by high-performance liquid chromatography with fluorescence detection. J. Chromatogr. 1986, 378, 329-336.
34. Chomczynski, P.; Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-cholroform extraction. Anal. Biochem. 1987, 162, 156-159.
35. Mosman, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxic assays. J. Immunol. Meth. 1983, 65, 55-63.
36. Lowry, O.H.; Rosenbrough, N.L.; Farr, A.L.; Randall, R.L. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193, 265-275.