Differentiated fibroblastic progenies of human embryonic stem cells for toxicology screening

Cloning and Stem Cells

Volumn 10, Issue 1, 2008, Pages 1-9

  Cao, Tong ^a,b   Lu, Kai ^a   Fu, Xin ^a   Heng, Boon Chin ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C;

ACCURACY; ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CELL IMMORTALIZATION; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN L 929; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYONIC STEM CELL; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; PHENOTYPE; PRIORITY JOURNAL; PROGENY; REPRODUCIBILITY; TOXICITY TESTING;

ALGORITHMS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; CYTOSTATIC AGENTS; DRUG EVALUATION, PRECLINICAL; EMBRYONIC STEM CELLS; FIBROBLASTS; GENE EXPRESSION PROFILING; HUMANS; MITOMYCIN; TOXICITY TESTS;

ANIMALIA;

EID: 40349087320     PISSN: 15362302     EISSN: None     Source Type: Journal    
DOI: 10.1089/clo.2007.0049     Document Type: Article

References (13)

1. Cai, J., Weiss, M.L., and Rao, M.S. (2004). In search of "stemness." Exp. Hematol. 32, 585-598.
2. Conley, B.J., Trounson, A.O., and Mollard, R. (2004). Human embryonic stem cells form embryoid bodies containing visceral endoderm-like derivatives. Fetal Diagn. Ther. 19, 218-223.
3. Cowan, C.A., Klimanskaya, I., McMahon, J., et al. (2004). Derivation of embryonic stem-cell lines from human blastocysts. N. Engl. J. Med. 350, 1353-1356.
4. Department of Health and Human Services USA. (2001). Stem cells: scientific progress and future research directions. Accessible at the following website: http://stemcells.nih.gov/info/scireport/2001report.htm (Date accessed: 22 November 2007).
5. Hay, R.J. (1996). Human cells and cell cultures: availability, authentication and future prospects. Hum. Cell. 9, 143-152.
6. International standard ISO-10993-5. (1999). Biological Evaluation of Medical Devices - Part 5: Tests for In Vitro Cytoxicity. (International Organization for Standardization, Geneva, Switzerland).
7. Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods. 65, 55-63.
8. Olivier, E.N., Rybicki, A.C., and Bouhassira, E.E. (2006). Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. Stem Cells. 24, 1914-1922.
9. Phelps, R.M., Johnson, B.E., Ihde, D.C., et al. (1996). NCI-Navy Medical Oncology Branch cell line data base. J. Cell. Biochem. Suppl. 24, 32-91.
10. Ready, T. (2001). NIH posts online ES-cell registry. Nat. Med. 7, 1262.
11. Reubinoff, B.E., Pera, M.F., Fong, C.Y., et al. (2000). Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18, 399-404.
12. Sinha, G. (2005). Cell biology. Human embryonic stem cells may be toxicology's new best friends. Science. 308, 1538.
13. Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., et al. (1998). Embryonic stem cell lines derived from human blastocysts. Science. 282, 1145-1147.