Numerical simulation of global hydro-dynamics in a pulsatile bioreactor for cardiovascular tissue engineering

Journal of Biomechanics

Volumn 41, Issue 5, 2008, Pages 953-959

  Shi, Yubing ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Bioreactor; Cardiovascular; Hydro dynamics; Numerical simulation; Pulsatile; Tissue engineering

Indexed keywords

BIOREACTORS; CARDIOVASCULAR SYSTEM; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; TISSUE ENGINEERING;

CARDIOVASCULAR TISSUE ENGINEERING; PULSATILE BIOREACTORS;

HYDRODYNAMICS;

ARTICLE; BIOREACTOR; CARDIOVASCULAR SYSTEM; ELASTICITY; FLOW RATE; HUMAN; HYDRODYNAMICS; MATHEMATICAL MODEL; PRESSURE MEASUREMENT; PRIORITY JOURNAL; PULSATILE FLOW; SIMULATION; TISSUE ENGINEERING;

BIOREACTORS; COMPUTER SIMULATION; ELASTICITY; MODELS, CARDIOVASCULAR; PULSATILE FLOW; TISSUE ENGINEERING;

EID: 40249102978     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2008.01.001     Document Type: Article

References (14)

1. Davidson, K.M., Sushil, S., Eggleton, C.D., Marten, M.R., 2003. Using computational fluid dynamics software to estimate circulation time distributions in bioreactors. Biotechnology Progress 19, 1480-1486.
2. Dubey H., Das S.K., and Panda T. Numerical simulation of a fully baffled biological reactor: the differential circumferential averaging mixing plane approach. Biotechnology and Bioengineering 95 4 (2006) 754-766
3. Guyton A.C. Textbook of Medical Physiology (1986), W.B. Saunders Company, Philadelphia
4. Hoerstrupa S.P., Zünda G., Sodian R., Schnell A.M., Grünenfeldera J., and Turina M.I. Tissue engineering of small caliber vascular grafts. European Journal of Cardio-Thoracic Surgery 20 (2001) 164-169
5. Narita Y., Hata K.-I., Kagami H., Usui A., Ueda M., and Ueda Y. Novel pulse duplicating bioreactor system for tissue-engineered vascular construct. Tissue Engineering 10 (2004) 1224-1233
6. Sharp M.K., and Dharmalingam R.K. Development of a hydraulic model of the human systemic circulation. ASAIO Journal 45 (1999) 535-540
7. Shi Y., and Korakianitis T. Numerical simulation of cardiovascular dynamics with left heart failure and in-series pulsatile ventricular assist device. Artificial Organs 30 (2006) 930-949
8. Shi Y., Yeo J.H., and Zhao Y. Numerical simulation of a systemic flow test rig. ASAIO Journal 50 (2004) 54-64
9. Singh H., Ang E.S., Lim T.T., and Hutmacher D.W. Flow modeling in a novel non-perfusion conical bioreactor. Biotechnology and Bioengineering 97 (2007) 1291-1299
10. Sodian R., Lemke T., Loebe M., Hoerstrup S.P., Potapov E.V., Hausmann H., Meyer R., and Hetzer R. New pulsatile bioreactor for fabrication of tissue-engineered patches. Journal of Biomedical Materials Research (Applied Biomaterials) 58 (2001) 401-405
11. Sodian R., Lemke T., Fritsche C., Hoerstrup S.P., Fu P., Potapov E.V., Hausmann H., and Hetzer R. Tissue-engineering bioreactors: a new combined cell-seeding and perfusion system for vascular tissue engineering. Tissue Engineering 8 (2002) 863-870
12. Ursino M. A mathematical model of the carotid baroregulation in pulsating conditions. IEEE Transactions on Biomedical Engineering 46 (1999) 382-392
13. Williams K.A., Saini S., and Wick T.M. Computational fluid dynamics modeling of steady-state momentum and mass transport in a bioreactor for cartilage tissue engineering. Biotechnology Progress 18 (2002) 951-963
14. Zeng Y., Lee T.-S., Yu P., Roy P., and Low H.-T. Mass transport and shear stress in a microchannel bioreactor: numerical simulation and dynamic similarity. Journal of Biomechanical Engineering 128 (2006) 185-193