Researching human oocyte cryopreservation: ethical issues

Fertility and Sterility

Volumn 89, Issue 3, 2008, Pages 523-528

  de Melo Martin, Inmaculada ^a   Cholst, Ina N ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

ethics; informed consent; Oocyte cryopreservation; research subjects

Indexed keywords

ARTICLE; CLINICAL PROTOCOL; CRYOPRESERVATION; FERTILIZATION IN VITRO; HEALTH PROGRAM; HUMAN; INFERTILITY; INFERTILITY THERAPY; INFORMED CONSENT; MEDICAL ETHICS; MEDICAL RESEARCH; OOCYTE; PATIENT SELECTION; PREGNANCY; PRIORITY JOURNAL; REPRODUCTION; RISK REDUCTION;

BIOMEDICAL RESEARCH; CRYOPRESERVATION; FEMALE; HUMAN EXPERIMENTATION; HUMANS; INFORMED CONSENT; OOCYTES; PATIENT SELECTION; REPRODUCTIVE TECHNIQUES, ASSISTED;

EID: 40249097620     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.03.039     Document Type: Article

References (50)

1. Centers for Disease Control and Prevention (CDC). 2003 Assisted Reproductive Technology Success Rates (2005), CDC, Atlanta
2. ESHRE. Assisted reproductive technology in Europe, 2002. Results generated from European registers by ESHRE. Hum Reprod 21 (2006) 1680-1697
3. Van Voorhis B.J. Outcomes from assisted reproductive technology. Obstet Gynecol 107 (2006) 183-200
4. Wright V.C., Schieve L.A., Reynolds M.A., and Jeng G. Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC). Assisted reproductive technology surveillance-United States, 2002. MMWR Surveill Summ 54 (2005) 1-24
5. Gosden L.V., and Yin H. Micromanipulation in assisted reproductive technology: intracytoplasmic sperm injection, assisted hatching, and preimplantation genetic diagnosis. Clin Obstet Gynecol 49 (2006) 73-84
6. Tan B.K., Vandekerckhove P., Kennedy R., and Keay S.D. Investigation and current management of recurrent IVF treatment failure in the UK. BJOG 112 (2005) 773-780
7. El-Toukhy T., and Taranissi M. Towards better quality research in recurrent implantation failure: standardizing its definition is the first step. Reprod Biomed Online 12 (2006) 383-385
8. Urman B., Yakin K., and Balaban B. Recurrent implantation failure in assisted reproduction: how to counsel and manage. B. Treatment options that have not been proven to benefit the couple. Reprod Biomed Online 11 (2005) 382-389
9. Lobo R.A. Potential options for preservation of fertility in women. N Engl J Med 353 (2005) 64-73
10. Shahine L.K., and Cedars M.I. Preimplantation genetic diagnosis does not increase pregnancy rates in patients at risk for aneuploidy. Fertil Steril 85 (2006) 51-56
11. Save my eggs, http://www.savemyeggs.com/the-freezing-of-human-oocytes-eggs.html; Extend Fertility, http://www.extendfertility.com; West Coast Fertility Centers, http://www.eggfreezing.com/egg_freezing.htm.
12. American Society for Reproductive Medicine (ASRM). Ovarian tissue and oocyte cryopreservation. Fertil Steril 82 (2004) 993-998
13. Miller F.G., and Brody H. A critique of clinical equipoise. Therapeutic misconception in the ethics of clinical trials. Hastings Cent Rep 33 (2003) 19-28
14. Brody H., and Miller F.G. The clinician-investigator: unavoidable but manageable tension. Kennedy Inst Ethics J 13 (2003) 329-346
15. Lidz C.W. The therapeutic misconception and our models of competency and informed consent. Behav Sci Law 24 (2006) 535-546
16. Emanuel E.J., Wendler D., and Grady C. What makes clinical research ethical?. JAMA 283 (2000) 2701-2711
17. Chen C. Pregnancy after human oocyte cryopreservation. Lancet 1 (1986) 884-886
18. Coticchio G., Bonu M.A., Borini A., and Flamigni C. Oocyte cryopreservation: a biological perspective. Eur J Obstet Gynecol Reprod Biol 115 (2004) S2-S7
19. Lucena E., Bernal D.P., Lucena C., Rojas A., Moran A., and Lucena A. Successful ongoing pregnancies after vitrification of oocytes. Fertil Steril 85 (2006) 108-111
20. Levi Setti P.E., Albani E., Novara P.V., Cesana A., and Morreale G. Cryopreservation of supernumerary oocytes in IVF/ICSI cycles. Hum Reprod 21 (2006) 370-375
21. Chen S.U., Lien Y.R., Chen H.F., Chang L.J., Tsai Y.Y., and Yang Y.S. Observational clinical follow-up of oocyte cryopreservation using a slow-freezing method with 1,2-propanediol plus sucrose followed by ICSI. Hum Reprod 20 (2005) 1975-1980
22. Fosas N., Marina F., Torres P.J., Jove I., Martin P., Perez N., et al. The births of five Spanish babies from cryopreserved donated oocytes. Hum Reprod 18 (2003) 1417-1421
23. Yang D., Winslow K.L., Blohm P.L., Brown S.E., Nguyen K., and Brubaker C. Oocyte donation using cryopreserved donor oocytes. Fertil Steril 78 (2002) S14-S15
24. Boldt J., Cline D., and McLaughlin D. Human oocyte cryopreservation as an adjunct to IVF-embryo transfer cycles. Hum Reprod 18 (2003) 1250-1255
25. Quintans C.J., Donaldson M.J., Bertolino M.V., and Pasqualini R.S. Birth of two babies using oocytes that were cryopreserved in a choline-based freezing medium. Hum Reprod 17 (2002) 3149-3152
26. Winslow K., Yang D., Blohm P., Brown S., Jossim P., and Nguyen K. Oocyte cryopreservation: a three year follow up of sixteen births. Fertil Steril 76 (2001) S120
27. Porcu E., Fabbri R., Damiano G., Giunchi S., Fratto R., Ciotti P.M., et al. Clinical experience and applications of oocyte cryopreservation. Mol Cell Endocrinol 169 (2000) 33-37
28. Kim S.S. Fertility preservation in female cancer patients: current developments and future directions. Fertil Steril 85 (2006) 1-11
29. Jemal A., Clegg L.X., Ward E., Ries L.A., Wu X., Jamison P.M., et al. Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival. Cancer 101 (2004) 3-27
30. Blatt J. Pregnancy outcome in long-term survivors of childhood cancer. Med Pediatr Oncol 33 (2003) 29-33
31. Simon B., Lee S.J., Partridge A.H., and Runowicz C.D. Preserving fertility after cancer. CA Cancer J Clin 55 (2005) 211-228
32. Shamonki M.I., and Oktay K. Oocyte and ovarian tissue cryopreservation: indications, techniques, and applications. Semin Reprod Med 23 (2005) 266-276
33. Lockwood G. Politics, ethics and economics: oocyte cryopreservation in the UK. Reprod Biomed Online 6 (2003) 151-153
34. Borini A., Sciajno R., Bianchi V., Sereni E., Flamigni C., and Coticchio G. Clinical outcome of oocyte cryopreservation after slow cooling with a protocol utilizing a high sucrose concentration. Hum Reprod 21 (2006) 512-517
35. Lee S.J., Schover L.R., Partridge A.H., Patrizio P., Wallace W.H., Hagerty K., et al. American Society of Clinical Oncology Recommendations on Fertility Preservation in Cancer Patients. J Clin Oncol 24 (2006) 2917-2931
36. FIGO Committee for the Ethical Aspects of Human Reproduction and Women's Health. Ethical considerations and recommendations on oocyte and ovarian cryopreservation. FIGO Committee for the Ethical Aspects of Human Reproduction and Women's Health. Int J Gynaecol Obstet 92 (2006) 335-336
37. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (NCPHSBBR). The Belmont Report. Ethical Principles and Guidelines for the Protection of Human Subjects of Research (1979), DHHS, Washington, DC
38. ICH Harmonised Tripartite Guideline. Guideline for good clinical practice. J Postgrad Med 47 (2002) 121-130
39. Dudzinski D.M. Ethical issues in fertility preservation for adolescent cancer survivors: oocyte and ovarian tissue cryopreservation. J Pediatr Adolesc Gynecol 17 (2004) 97-102
40. Nurgat Z.A., Craig W., Campbell N.C., Bissett J.D., Cassidy J., and Nicolson M.C. Patient motivations surrounding participation in phase I and phase II clinical trials of cancer chemotherapy. Br J Cancer 92 (2005) 1001-1005
41. Schutta K.M., and Burnett C.B. Factors that influence a patient's decision to participate in a phase I cancer clinical trial. Oncol Nurs Forum 27 (2000) 1435-1438
42. Edwards S.J., Lilford R.J., and Hewison J. The ethics of randomised controlled trials from the perspectives of patients, the public, and healthcare professionals. BMJ 317 (1998) 1209-1212
43. Appelbaum P.S., Lidz C.W., and Grisso T. Therapeutic misconception in clinical research: frequency and risk factors. IRB 26 (2004) 1-8
44. Daugherty C.K., Banik D.M., Janish L., and Ratain M.J. Quantitative analysis of ethical issues in phase I trials: a survey interview of 144 advanced cancer patients. IRB 22 (2000) 6-14
45. Glannon W. Phase I oncology trials: why the therapeutic misconception will not go away. J Med Ethics 32 (2006) 252-255
46. Zaner R. Trust and the patient-physician relationship. In: Pellegrino E., Veatch R., and Langan J. (Eds). Ethics, trust, and the professions: philosophical and cultural aspects (1991), Georgetown University Press, Washington, DC 45-57
47. Miller F.G., and Rosenstein D.L. The therapeutic orientation to clinical trials. New Engl J Med 348 (2003) 1383-1386
48. Fried E. The therapeutic misconception, beneficence, and respect. Account Res 8 (2001) 331-348
49. Lidz C.W., Appelbaum P.S., Grisso T., and Renaud M. Therapeutic misconception and the appreciation of risks in clinical trials. Soc Sci Med 58 (2004) 1689-1697
50. Boggio A. Italy enacts new law on medically assisted reproduction. Hum Reprod 20 (2005) 1153-1157