Associations between electrocardiographic interval durations and coronary artery calcium scores: The Diabetes Heart Study

PACE - Pacing and Clinical Electrophysiology

Volumn 31, Issue 3, 2008, Pages 314-321

  Nelson, Matthew R ^a   Daniel, Kurt R ^a   Carr, J Jeffrey ^a   Freedman, Barry I ^a   Prineas, Ronald J ^a   Bowden, Donald W ^a   Herrington, David M ^a,b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST BAPTIST HEALTH   (United States)

Author keywords

Coronary calcium; Electrocardiogram; QT interval

Indexed keywords

ADULT; AGED; ARTERY CALCIFICATION; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ELECTROCARDIOGRAM; ELECTROCARDIOGRAPHY; FEMALE; HEART BUNDLE BRANCH BLOCK; HEART REPOLARIZATION; HUMAN; JT INTERVAL; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL ANALYSIS; MULTIVARIATE ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; QRS COMPLEX; QT INTERVAL; RISK ASSESSMENT; RISK FACTOR; UNITED STATES; UNIVARIATE ANALYSIS;

ARRHYTHMIAS, CARDIAC; CALCINOSIS; COMORBIDITY; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; NORTH CAROLINA; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; SEX DISTRIBUTION;

EID: 40149100819     PISSN: 01478389     EISSN: 15408159     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2008.00991.x     Document Type: Article

References (49)

1. Schouten EG, Dekker JM, Meppelink P, Kok FJ, Vandenbroucke JP, Pool J. QT interval prolongation predicts cardiovascular mortality in an apparently healthy population. Circulation 1991 84 : 1516 1523.
2. Dekker JM, Schouten EG, Klootwijk P, Pool J, Kromhout D. Association between QT interval and coronary heart disease in middle-aged and elderly men. The Zutphen Study. Circulation 1994 90 : 779 785.
3. de Bruyne MC, Hoes AW, Kors JA, Hofman A, van Bemmel JH, Grobbee DE. Prolonged QT interval predicts cardiac and all-cause mortality in the elderly. The Rotterdam Study. Eur Heart J 1999 20 : 278 284.
4. Robbins J, Nelson JC, Rautaharju PM, Gottdiener JS. The association between the length of the QT interval and mortality in the Cardiovascular Health Study. Am J Med 2003 115 : 689 694.
5. Cardoso CR, Salles GF, Deccache W. Prognostic value of QT interval parameters in type 2 diabetes mellitus: Results of a long-term follow-up prospective study. J Diabetes Complications 2003 17 : 169 178.
6. Linnemann B, Janka HU. Prolonged QTc interval and elevated heart rate identify the type 2 diabetic patient at high risk for cardiovascular death. The Bremen Diabetes Study. Exp Clin Endocrinol Diabetes 2003 111 : 215 222.
7. Dekker JM, Crow RS, Hannan PJ, Schouten EG, Folsom AR. Heart rate-corrected QT interval prolongation predicts risk of coronary heart disease in black and white middle-aged men and women: The ARIC study. J Am Coll Cardiol 2004 43 : 565 571.
8. Benoit SR, Mendelsohn AB, Nourjah P, Staffa JA, Graham DJ. Risk factors for prolonged QTc among US adults: Third National Health and Nutrition Examination Survey. Eur J Cardiovasc Prev Rehabil 2005 12 : 363 368.
9. Friedman PL, Fenoglio JJ, Wit AL. Time course for reversal of electrophysiological and ultrastructural abnormalities in subendocardial Purkinje fibers surviving extensive myocardial infarction in dogs. Circ Res 1975 36 : 127 144.
10. Spear JF, Michelson EL, Moore EN. Cellular electrophysiologic characteristics of chronically infarcted myocardium in dogs susceptible to sustained ventricular tachyarrhythmias. J Am Coll Cardiol 1983 1 : 1099 1110.
11. Gardner PI, Ursell PC, Fenoglio JJ, Jr., Wit AL. Electrophysiologic and anatomic basis for fractionated electrograms recorded from healed myocardial infarcts. Circulation 1985 72 : 596 611.
12. Ursell PC, Gardner PI, Albala A, Fenoglio JJ, Jr., Wit AL. Structural and electrophysiological changes in the epicardial border zone of canine myocardial infarcts during infarct healing. Circ Res 1985 56 : 436 451.
13. Lurie KG, Argentieri TM, Sheldon J, Frame LH, Matschinsky FM. Metabolism and electrophysiology in subendocardial Purkinje fibers after infarction. Am J Physiol 1987 253 : H662 H670.
14. Veglio M, Borra M, Stevens LK, Fuller JH, Perin PC. The relation between QTc interval prolongation and diabetic complications. The EURODIAB IDDM Complication Study Group. Diabetologia 1999 42 : 68 75.
15. Veglio M, Bruno G, Borra M, Macchia G, Bargero G, D'Errico N, Pagano GF, et al. Prevalence of increased QT interval duration and dispersion in type 2 diabetic patients and its relationship with coronary heart disease: A population-based cohort. J Intern Med 2002 251 : 317 324.
16. Hesse B, Diaz LA, Snader CE, Blackstone EH, Lauer MS. Complete bundle branch block as an independent predictor of all-cause mortality: Report of 7,073 patients referred for nuclear exercise testing. Am J Med 2001 110 : 253 259.
17. Elhendy A, Hammill SC, Mahoney DW, Pellikka PA. Relation of QRS duration on the surface 12-lead electrocardiogram with mortality in patients with known or suspected coronary artery disease. Am J Cardiol 2005 96 : 1082 1088.
18. Bauer A, Watanabe MA, Barthel P, Schneider R, Ulm K, Schmidt G. QRS duration and late mortality in unselected post-infarction patients of the revascularization era. Eur Heart J 2006 27 : 427 433.
19. Lauer MS, Martino D, Ishwaran H, Blackstone EH. Quantitative measures of electrocardiographic left ventricular mass, conduction, and repolarization, and long-term survival after coronary artery bypass grafting. Circulation 2007 116 : 888 893.
20. Desai AD, Yaw TS, Yamazaki T, Kaykha A, Chun S, Froelicher VF. Prognostic significance of quantitative QRS duration. Am J Med 2006 119 : 600 606.
21. Iuliano S, Fisher SG, Karasik PE, Fletcher RD, Singh SN. QRS duration and mortality in patients with congestive heart failure. Am Heart J 2002 143 : 1085 1091.
22. Kalra PR, Sharma R, Shamim W, Doehner W, Wensel R, Bolger AP, Genth-Zotz S, et al. Clinical characteristics and survival of patients with chronic heart failure and prolonged QRS duration. Int J Cardiol 2002 86 : 225 231.
23. Festa A, D'Agostino R, Jr., Rautaharju P, O'Leary DH, Rewers M, Mykkänen L, Haffner SM. Is QT interval a marker of subclinical atherosclerosis in nondiabetic subjects? The Insulin Resistance Atherosclerosis Study (IRAS). Stroke 1999 30 : 1566 1571.
24. Takebayashi K, Aso Y, Matsutomo R, Wakabayashi S, Inukai T. Association between the corrected QT intervals and combined intimal-medial thickness of the carotid artery in patients with type 2 diabetes. Metabolism 2004 53 : 1152 1157.
25. Wagenknecht LE, Bowden DW, Carr JJ, Langefeld CD, Freedman BI, Rich SS. Familial aggregation of coronary artery calcium in families with type 2 diabetes. Diabetes 2001 50 : 861 866.
26. Rautaharju PM, Park LP, Chaitman BR, Rautaharju F, Zhang ZM. The Novacode criteria for classification of ECG abnormalities and their clinically significant progression and regression. J Electrocardiol 1998 31 : 157 187.
27. Marquette R. 12SL ECG Analysis Program: Physician's Guide, Revision B. GE Med Syst 2006 3 12 to 3 16.
28. Bazett HC. An analysis of the time relations of the electrocardiograms. Heart 1920 7 : 353 370.
29. Prineas RJ, Crow RS, Blackburn H. The Minnesota Code: Manual of electrocardiographic findings. Boston : 1982.
30. Carr JJ, Nelson JC, Wong ND, McNitt-Gray M, Arad Y, Jacobs DR, Jr., Sidney S, et al. Calcified coronary artery plaque measurement with cardiac CT in population-based studies: Standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) study. Radiology 2005 234 : 35 43.
31. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 1986 42 : 121 130.
32. Janse MJ, Kleber AG. Electrophysiological changes and ventricular arrhythmias in the early phase of regional myocardial ischemia. Circ Res 1981 49 : 1069 1081.
33. Wilde AA, Aksnes G. Myocardial potassium loss and cell depolarisation in ischaemia and hypoxia. Cardiovasc Res 1995 29 : 1 15.
34. Das MK, Khan B, Jacob S, Kumar A, Mahenthiran J. Significance of a fragmented QRS complex versus a Q wave in patients with coronary artery disease. Circulation 2006 113 : 2495 2501.
35. Mautner GC, Mautner SL, Froehlich J, Feuerstein IM, Proschan MA, Roberts WC, Doppman JL. Coronary artery calcification: Assessment with electron beam CT and histomorphometric correlation. Radiology 1994 192 : 619 623.
36. Baumgart D, Schmermund A, Goerge G, Haude M, Ge J, Adamzik M, Sehnert C, et al. Comparison of electron beam computed tomography with intracoronary ultrasound and coronary angiography for detection of coronary atherosclerosis. J Am Coll Cardiol 1997 30 : 57 64.
37. Wang L, Jerosch-Herold M, Jacobs DR, Jr., Shahar E, Detrano R, Folsom AR. Coronary artery calcification and myocardial perfusion in asymptomatic adults: The MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol 2006 48 : 1018 1026.
38. Schneider JF, Thomas HE, Jr., Kreger BE, McNamara PM, Kannel WB. Newly acquired left bundle-branch block: The Framingham study. Ann Intern Med 1979 90 : 303 310.
39. Ghostine S, Caussin C, Daoud B, Habis M, Perrier E, Pesenti-Rossi D, Sigal-Cinqualbre A, et al. Non-invasive detection of coronary artery disease in patients with left bundle branch block using 64-slice computed tomography. J Am Coll Cardiol 2006 48 : 1929 1934.
40. Ahnve S, Sullivan M, Myers J, Froelicher V. Computer analysis of exercise-induced changes in QRS duration in patients with angina pectoris and in normal subjects. Am Heart J 1986 111 : 903 908.
41. Michaelides A, Ryan JM, Bacon JP, Pozderac R, Toutouzas P, Boudoulas H. Exercise-induced QRS changes (Athens QRS score) in patients with coronary artery disease: a marker of myocardial ischemia. J Cardiol 1995 26 : 263 272.
42. Cantor A, Yosefy C, Potekhin M, Ilia R, Keren A. The value of changes in QRS width and in ST-T segment during exercise test in hypertrophic cardiomyopathy for identification of associated coronary artery disease. Int J Cardiol 2006 112 : 99 104.
43. Toth A, Marton Z, Czopf L, kesmarky G, Halmosi R, Juricskay I, Habon T, et al. QRS Score: a composite index of exercise-induced changes in the Q, R, and S waves during exercise stress testing in patients with ischemic heart disease. Ann Noninvasive Electrocardiol 2001 6 : 310 318.
44. Carlsson MB, Tragardh E, Engblom H, Hedström E, Wagner G, Pahlm O, Arheden H. Left ventricular mass by 12-lead electrocardiogram in healthy subjects: Comparison to cardiac magnetic resonance imaging. J Electrocardiol 2006 39 : 67 72.
45. Dhingra R, Ho Nam B, Benjamin EJ, Wang TJ, Larson MG, D'Agostino RB Sr., Levy D, et al. Cross-sectional relations of electrocardiographic QRS duration to left ventricular dimensions: The Framingham Heart Study. J Am Coll Cardiol 2005 45 : 685 689.
46. Palmieri V, Okin PM, de Simone G, Bella JN, Wachtell K, Gerdts E, Boman K, et al. Electrocardiographic characteristics and metabolic risk factors associated with inappropriately high left ventricular mass in patients with electrocardiographic left ventricular hypertrophy: The LIFE Study. J Hypertens 2007 25 : 1079 1085.
47. Okin PM, Roman MJ, Devereux RB, Kligfield P. Gender differences and the electrocardiogram in left ventricular hypertrophy. Hypertension 1995 25 : 242 249.
48. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002 288 : 321 333.
49. Christian RC, Harrington S, Edwards WD, Oberg AL, Fitzpatrick LA. Estrogen status correlates with the calcium content of coronary atherosclerotic plaques in women. J Clin Endocrinol Metab 2002 87 : 1062 1067.