Electrocardiographic characteristics and metabolic risk factors associated with inappropriately high left ventricular mass in patients with electrocardiographic left ventricular hypertrophy: The LIFE study

Journal of Hypertension

Volumn 25, Issue 5, 2007, Pages 1079-1085

  Palmieri, Vittorio ^a,h   Okin, Peter M ^a   Simone, Giovanni De ^a,b   Bella, Jonathan N ^a   Wachtell, Kristian ^a,c   Gerdts, Eva ^d   Boman, Kurt ^e   Nieminen, Markku S ^f   Dahlöf, Björn ^g   Devereux, Richard B ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b FEDERICO II UNIVERSITY HOSPITAL   (Italy)

^c GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^e UMEÅ UNIVERSITY   (Sweden)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^g SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^h ASL Napoli 1   (Italy)

Author keywords

Echocardiography; Electrocardiography; Hypertension; Hypertrophy; Risk factors

Indexed keywords

ADULT; AGED; ARTICLE; BODY MASS; BODY SIZE; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE URINE LEVEL; DIABETES MELLITUS; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; FEMALE; GEOMETRY; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; PREVALENCE; PRIORITY JOURNAL; QRS COMPLEX; RISK FACTOR; STATISTICAL MODEL; SYSTOLIC BLOOD PRESSURE; UNIVARIATE ANALYSIS; WORKLOAD;

EID: 34147123809     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e3280825638     Document Type: Article

References (34)

1. De Simone G, Devereux RB, Kimball TR, Mureddu GF, Roman MJ, Contaldo F, et al. Interaction between body size and cardiac workload: influence on left ventricular mass during body growth and adulthood. Hypertension 1998; 31:1077-1082.
2. Palmieri V, de Simone G, Roman MJ, Schwartz JE, Pickering TG, Devereux RB. Ambulatory blood pressure and metabolic abnormalities in hypertensive subjects with inappropriately high left ventricular mass [Erratum in Hypertension 2000; 36:147]. Hypertension 1999; 34:1032-1040.
3. Palmieri V, Wachtell K,Gerdts E, Bella JN, Papademetriou V, Tuxen C, et al. Left ventricular function and hemodynamic features of inappropriate left ventricular hypertrophy in patients with systemic hypertension: the LIFE Study. Am Heart J 2001; 141:784-791.
4. De Simone G, Kitzman DW, Palmieri V, Liu JE, Oberman A, Hopkins PN, et al. Association of inappropriate left ventricular mass with systolic and diastolic dysfunction: the HyperGEN study. Am J Hypertens 2004; 17:828-833.
5. Palmieri V, Wachtell K, Bella JN, Gerdts E, Papademetriou V, Nieminen MS, et al. Usefulness of the assessment of the appropriateness of left ventricular mass to detect left ventricular systolic and diastolic abnormalities in absence of echocardiographic left ventricular hypertrophy: the LIFE study. J Hum Hypertens 2004; 18:423-430.
6. Celentano A, Palmieri V, Di Palma EN, Pietropaolo I, Crivaro M, Mureddu GF, et al. Inappropriate left ventricular mass in normotensive and hypertensive patients. Am J Cardiol 2001; 87:361-363.
7. Mureddu GF, Pasanisi F, Palmieri V, Celentano A, Contaldo F, de Simone G. Appropriate or inappropriate left ventricular mass in the presence or absence of prognostically adverse left ventricular hypertrophy. J Hypertens 2001; 19:1113-1119.
8. De Simone G, Devereux RB, Palmieri V, Bella JN, Oberman A, Kitzman DW, et al. Influence of fat-free mass on detection of appropriateness of left ventricular mass: the HyperGEN Study. J Hypertens 2003; 21:1747-1752.
9. De Simone G, Verdecchia P, Pede S, Gorini M, Maggioni AP. Prognosis of inappropriate left ventricular mass in hypertension: the MAVI Study. Hypertension 2002; 40:470-476.
10. Okin PM, Roman MJ, Lee ET, Galloway JM, Howard BV, Devereux RB. Combined echocardiographic left ventricular hypertrophy and electrocardiographic ST depression improve prediction of mortality in American Indians. The Strong Heart Study. Hypertension 2004; 43:769-774.
11. Vester EG, Kuhls S, Ochiulet-Vester J, Vogt M, Strauer BE. Electrophysiological and therapeutic implications of cardiac arrhythmias in hypertension. Eur Heart J 1992; 13 (Suppl. D):70-81.
12. Okin PM, Devereux RB, Nieminen MS, Jern S,Oikarinen L, Viitasalo M, et al. Electrocardiographic strain pattern and prediction of new-onset congestive heart failure in hypertensive patients: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study. Circulation 2006; 113:67-73.
13. Galderisi M, de Simone G, Cicala S, De Simone L, D'Errico A, Caso P, et al. Coronary flow reserve in hypertensive patients with appropriate or inappropriate left ventricular mass. J Hypertens 2003; 21:2183-2188.
14. Palmieri V, Okin PM, Bella JN, Gerdts E, Wachtell K, Gardin J, et al. Echocardiographic wall motion abnormalities in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE Study. Hypertension 2003; 41:75-82.
15. Dahlöf B, Devereux RB, Julius S, Kjeldsen SE, Beevers G, de Faire U, et al. Characteristics of 9194 patients with left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint Reduction in Hypertension. Hypertension 1998; 32:989-997.
16. Devereux RB, Bella J, Boman K, Gerdts E, Nieminen MS, Rokkedal J, et al. Echocardiographic left ventricular geometry in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE Study. Blood Press 2001; 10:74-82.
17. Okin PM, Devereux RB, Nieminen MS, Jern S,Oikarinen L, Viitasalo M, et al. Electrocardiographic strain pattern and prediction of cardiovascular morbidity and mortality in hypertensive patients. Hypertension 2004; 44:48-54.
18. Palmieri V, Dahlöf B, DeQuattro V, Sharpe N, Bella JN, de Simone G, et al. Reliability of echocardiographic assessment of left ventricular structure and function: the PRESERVE study. J Am Coll Cardiol 1999; 34:1625-1632.
19. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978; 58:1072-1083.
20. Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr 1989; 2:358-367.
21. Devereux RB, Roman JM. Evaluation of cardiac and vascular structure by echocardiography and other noninvasive techniques. In: Laragh JH, Brenner BM, editors. Hypertension: pathophysiology, diagnosis, treatment. New York, NY: Raven Press; 1995. pp. 1969-1985.
22. Devereux RB, Alonso DR, Lutas EM, Gottlieb GJ, Campo E, Sachs I, et al. Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol 1986; 57:450-458.
23. De Simone G, Daniels SR, Devereux RB, Meyer RA, Roman MJ, de Divitiis O, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 1992; 20:1251-1260.
24. Palmieri V, de Simone G, Arnett DK, Bella JN, Kitzman DW, Oberman A, et al. Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study). Am J Cardiol 2001; 88:1163-1168.
25. Devereux RB, Roman MJ, Paranicas M, O'Grady MJ, Wood EA, Howard BV, et al. Relations of Doppler stroke volume and its components to left ventricular stroke volume in normotensive and hypertensive American Indians: the Strong Heart Study. Am J Hypertens 1997; 10:619-628.
26. Deckert T, Feldt-Rasmussen B, Borch-Johnsen K, Jensen T, Kofoed-Enevoldsen A. Albuminuria reflects widespread vascular damage. The Steno hypothesis. Diabetologia 1989; 32:219-226.
27. Sundstrom J, Lind L, Arnlov J, Zethelius B, Andren B, Lithell HO. Echocardiographic and electrocardiographic diagnoses of left ventricular hypertrophy predict mortality independently of each other in a population of elderly men. Circulation 2001; 103:2346-2351.
28. Palmieri V, Okin PM, Bella JN, Wachtell K, Oikarinen L, Gerdts E, et al. Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: the LIFE study. J Hypertens 2006; 24:2079-2084.
29. Okin PM, Devereux RB, Nieminen MS, Jern S, Oikarinen L, Viitasalo M, et al. Relationship of the electrocardiographic strain pattern to left ventricular structure and function in hypertensive patients: the LIFE study. Losartan Intervention For End point. J Am Coll Cardiol 2001; 38:514-520.
30. Pech HJ, Witte J, Romaniuk R, Parsi RA, Porstmann W. Left ventricular mass in coronary artery disease without hypertension. Haemodynamic and angiocardiographic study. Br Heart J 1974; 36:362-367.
31. de Simone G, Palmieri V, Koren MJ, Mensah GA, Roman JM, Devereux RB. Prognostic implications of the compensatory nature of left ventricular mass in arterial hypertension. J Hypertens 2001; 19:1-7.
32. Kozakova M, de Simone G, Morizzo C, Palombo C. Coronary vasodilator capacity and hypertension-induced increase in left ventricular mass. Hypertension 2003; 41:224-229.
33. Pedrinelli R, Dell'Omo G, Penno G, Di Bello V, Giorgi D, Pellegrini G, et al. Microalbuminuria, a parameter independent of metabolic influences in hypertensive men. J Hypertens 2003; 21:1163-1169.
34. Okin PM, Jern S, Devereux RB, Kjeldsen SE, Dahlof B, for the LIFE Study Group. Effect of obesity on electrocardiographic left ventricular hypertrophy in hypertensive patients: the Losartan Intervention For Endpoint (LIFE) Reduction in Hypertension Study. Hypertension 2000; 35:13-18.