Direct binding of ligandin to uridine 5′-diphosphate glucuronosyltransferase 1A1

Hepatology Research

Volumn 38, Issue 4, 2008, Pages 402-409

  Akizawa, Emi ^a   Koiwai, Kotaro ^a   Hayano, Takahide ^a   Maezawa, So ^a   Matsushita, Toyofumi ^a   Koiwai, Osamu ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Bilirubin; Endoplasmic reticulum; Glutathione S transferase; Hepatocytes; Ligandin; Uridine 5 diphosphate glucuronosyltransferase

Indexed keywords

ALBUMIN; BILIRUBIN; GLUCURONOSYLTRANSFERASE 1A1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A2; HEME; LIGANDIN;

ARTICLE; BINDING SITE; CELL FRACTIONATION; CIRCULATION; CONTROLLED STUDY; CYTOSOLIC FRACTION; ENDOPLASMIC RETICULUM; ENZYME BINDING; GLUCURONIDATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIVER; LIVER CELL; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT; SOLUBILIZATION; SPLEEN;

EID: 40049109689     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2007.00285.x     Document Type: Article

References (27)

1. Chowdhury JR, Chowdhury NR, Wolkoff AW et al. The Liver: Biology and Pathobiology, 3rd edn. New York: Raven Press, 1994; 471-504.
2. Scharschmidt BF, Waggoner JG, Berk PD et al. Hepatic organic anion uptake in the rat. J Clin Invest 1975; 56: 1280-92.
3. Arias IM, Johnson L, Wolfson S et al. Biliary excretion of injected conjugated and unconjugated bilirubin by normal and Gunn rats. Am J Physiol 1961; 200: 1091-4.
4. Senafi SB, Clarke DJ, Burchell B et al. UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation. Biochem 1994; 303: 233-40.
5. Kamisako T, Leier I, Cui Y et al. Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2. Hepatology 1999; 30: 485-90.
6. Jedlitschky G, Leier I, Buchholz U et al. ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem 1997; 327: 305-10.
7. Habig HW, Pabst JM, Fleishner G, Gatmaitan Z, Arias IM, Jakoby WB. The identification of glutathione S-transferase B with ligandin, a major binding protein of liver. Proc Natl Acad Sci USA 1974; 71: 3879-82.
8. Simons CP, Vander Jagt DL. Bilirubin binding to human liver ligandin (glutathione S-transferase). J Biol Chem 1979; 255: 4740-4.
9. Jansen PLM, Mulder GJ, Burchel B, Bock KW. New developments in glucuronidation research: Report of a workshop on "glucuronidation, its role in health and disease". Hepatology 1992; 15: 532-44.
10. Emi Y, Ikushiro S, Iyanagi T. Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex. J Biochem 1995; 117: 392-99.
11. Peters WH, Jansen PL, Nauta H. The molecular weights of UDP-glucuronyl-transferase determined with radiation-inactivation analysis. A molecular model of bilirubin UDP-glucuronyltransferase. J Biol Chem 1984; 259: 11701-5.
12. Koiwai O, Nishizawa M, Hasada K et al. Gilbert's syndrome is caused by a heterozygous missense mutation in the gene for bilirubin UDP-glucuronosyltransferase. Hum Mol Genet 1995; 4: 1183-6.
13. Ishii Y, Miyoshi A, Watanabe R et al. Simultaneous expression of guinea pig UDP-glucuronosyltransferase 2B21 and 2B22 in COS-7 cells enhances UDP-glucuronosyltransferas 2B21-catalyzed morphine-6-glucuronide formation. Mol Phermacol 2001; 60: 1040-8.
14. Ikushiro S, Emi Y, Iyanagi T et al. Protein-protein interactions between UDP-glucuronosyltransferase isozymes in rat hepatic microsomes. Biochemistry 1997; 36: 7154-61.
15. Ghosh SS, Sappal BS, Kalpana GW et al. Homodimerization of human bilirubin-uridine-diphosphoglucuronate glucuronosyltransferase 1 (UGT1A1) and its functional implications. J Biochem 2001; 276: 42108-15.
16. Pemble SE, Wardle AF, Taylor JB et al. Characterization by the cloning of rat mitochondrial GST and identification of a human homologue. Biochem J 1996; 319: 749-54.
17. Guo J, Zimniak L, Zimniak P et al. Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme. Biochem J 2002; 366: 817-24.
18. Board PG, Coggan M, Chelvanayagam G et al. Identification, characterization, and crystal structure of the Omega class glutathione transferases. J Biol Chem 2000; 275: 24798-806.
19. Thomson AM, Meyer DJ, Hayes JD et al. Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase. Biochem J 1998; 333: 317-25.
20. Meyer DJ, Coles B, Pemble SE et al. Theta, a new class of glutathione transferases purified from rat and man. Biochem J 1991; 274: 409-14.
21. Board PG, Chelvanayagam G, Jermiin LS et al. Identification of novel glutathione transferases and polymorphic variants by expressed sequence tag database analysis. Drug Metab Dispos 2001; 29: 544-7.
22. Pemble SE, Taylor JB. An evolutionary perspective on glutathione transferases inferred from class theta glutathione transferase cDNA. Biochem J 1992; 287: 957-63.
23. Gallagher EP, Gardner JL, Barber DS. Several glutathione S-transferase isozymes that protect against oxidative injury are expressed in human liver mitochondria. Biochem Pharm 2006; 71: 1619-28.
24. Taura K, Naito E, Ishii Y et al. Cytochrome P450 1A1 (CYP1A1) inhibitor α naphthoflavone interferes with UDP-glucuronosyl-transferase (UGT) activity in intact but not in permeabilized hepatic microsome from 3-metylcholanthrene-treated rats: Possible involvement of UGT-P450 interactions. Biol Pharm Bull 2004; 27: 56-60.
25. Ahn T, Guengerich FP, Yun CH et al. Membrane insertion of cytochrome P450 1A2 promoted by anionic phospholipids. Biochemistry 1998; 37: 12860-6.
26. Satoh K, Kitahara A, Sato K et al. Identification of heterogeneous and microheterogeneous subunits of glutathione S-transferase in rat liver cytosol. Arch Biochem Biophys 1985; 242: 104-10.
27. Zucker SD, Goessling W, Ransil BJ, Gollan JL. Influence of glutathione S-transferase B (ligandin) on the intermembrane transfer of bilirubin. Implications for the intracellular transport of nonsubstrate ligands in hepatocytes. J Clin Invest 1995; 96: 1927-35.