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Volumn 61, Issue 3, 2008, Pages 621-628

Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic-pharmacodynamic models with Monte Carlo simulation

Author keywords

lactam antibiotics; Acinetobacter; Computer modelling; Pseudomonas; Stochastic

Indexed keywords

AMINOGLYCOSIDE DERIVATIVE; ANTIINFECTIVE AGENT; AZTREONAM; BETA LACTAM; CARBAPENEM DERIVATIVE; CEFEPIME; CEFTAZIDIME; CEFTIZOXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; ERTAPENEM; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; MONOBACTAM DERIVATIVE; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; QUINOLONE DERIVATIVE; TOBRAMYCIN;

EID: 40049093397     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm536     Document Type: Article
Times cited : (105)

References (44)
  • 2
    • 0021628275 scopus 로고
    • Mathematical models of particle deposition in the human respiratory tract
    • Heyder J, Rudolf G. Mathematical models of particle deposition in the human respiratory tract. J Aerosol Sci 1984; 15: 697-707.
    • (1984) J Aerosol Sci , vol.15 , pp. 697-707
    • Heyder, J.1    Rudolf, G.2
  • 3
    • 30544440040 scopus 로고    scopus 로고
    • Ambrose Monte Carlo simulation in the evaluation of susceptibility breakpoints: PredIcting the future: insights from the society of infectious diseases pharmacists. Pharmacotherapy 2006; 26: 129-34.
    • Ambrose PG. Monte Carlo simulation in the evaluation of susceptibility breakpoints: PredIcting the future: insights from the society of infectious diseases pharmacists. Pharmacotherapy 2006; 26: 129-34.
  • 4
    • 27744468387 scopus 로고    scopus 로고
    • Comparison of β-lactam regimens for the treatment of Gram-negative pulmonary infections in the intensive care unit based on pharmacokinetics/pharmacodynamics
    • Burgess DS, Frei CR. Comparison of β-lactam regimens for the treatment of Gram-negative pulmonary infections in the intensive care unit based on pharmacokinetics/pharmacodynamics. J Antimicrob Chemother 2005; 56: 893-8.
    • (2005) J Antimicrob Chemother , vol.56 , pp. 893-898
    • Burgess, D.S.1    Frei, C.R.2
  • 5
    • 2142760947 scopus 로고    scopus 로고
    • Antimicrobial pharmacodynamics: Critical interactions of 'bug and drug'
    • Drusano GL. Antimicrobial pharmacodynamics: Critical interactions of 'bug and drug': Nat Rev Microbiol 2004; 2: 269-300.
    • (2004) Nat Rev Microbiol , vol.2 , pp. 269-300
    • Drusano, G.L.1
  • 6
    • 0033794265 scopus 로고    scopus 로고
    • Pharmacodynamics in the study of drug resistance and establishing in vitro susceptibility breakpoints: Ready for prime time
    • Dudley MN, Ambrose PG. Pharmacodynamics in the study of drug resistance and establishing in vitro susceptibility breakpoints: Ready for prime time. Curr Opin Microbiol 2000; 3: 515-21.
    • (2000) Curr Opin Microbiol , vol.3 , pp. 515-521
    • Dudley, M.N.1    Ambrose, P.G.2
  • 7
    • 0041527129 scopus 로고    scopus 로고
    • European harmonization of MIC breakpoints for antimicrobial susceptibility testing of bacteria
    • Kahlmeter G,. Brown DF, Goldstein FW et al, European harmonization of MIC breakpoints for antimicrobial susceptibility testing of bacteria: J Antimicrob Chemother 2003; 52: 145-8.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 145-148
    • Kahlmeter, G.1    Brown, D.F.2    Goldstein, F.W.3
  • 8
    • 3042666087 scopus 로고    scopus 로고
    • Optimizing Pharmacodynamic target attainment using the MYSTIC antibiogram: Data collected in North America in 2002
    • Kuti JL, Nightingale CH, Nicolau DP. Optimizing Pharmacodynamic target attainment using the MYSTIC antibiogram: Data collected in North America in 2002. Antimicrob Agents Chemother 2004; 48: 2464-70.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2464-2470
    • Kuti, J.L.1    Nightingale, C.H.2    Nicolau, D.P.3
  • 9
    • 0035884762 scopus 로고    scopus 로고
    • In vitro models, in vivo models, and pharmacokinetics: What can we learn from in vitro models?
    • MacGowan A, Rogers C, Bowker K. In vitro models, in vivo models, and pharmacokinetics: What can we learn from in vitro models? Clin Infect Dis 2001; 33 Suppl 3: S214-20.
    • (2001) Clin Infect Dis , vol.33 , Issue.SUPPL. 3
    • MacGowan, A.1    Rogers, C.2    Bowker, K.3
  • 10
    • 0347063839 scopus 로고    scopus 로고
    • Impact of pharmacodynamics on breakpoint selection for susceptibility testing
    • Mouton JW. Impact of pharmacodynamics on breakpoint selection for susceptibility testing. Infect Dis Clin North Am 2003; 17: 579-98.
    • (2003) Infect Dis Clin North Am , vol.17 , pp. 579-598
    • Mouton, J.W.1
  • 11
    • 4344584316 scopus 로고    scopus 로고
    • Designing fluoroquinolone breakpoints for Streptococcus pneumoniae by using genetics instead of pharmacokinetics-pharmacodynamics
    • Smith HJ, Noreddin AM, Siemens CG et. al. Designing fluoroquinolone breakpoints for Streptococcus pneumoniae by using genetics instead of pharmacokinetics-pharmacodynamics. Antimicrob Agents Chemother 2064; 48: 3630-5.
    • (2064) Antimicrob Agents Chemother , Issue.48 , pp. 3630-3635
    • Smith, H.J.1    Noreddin, A.M.2    Siemens, C.G.3    et., al.4
  • 12
    • 0037764683 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of cefepime in patients with various degrees of renal function
    • Tam VH, McKinnon PS, Akins RL et al. Pharmacokinetics and pharmacodynamics of cefepime in patients with various degrees of renal function. Antimicrob Agents Chemother 2003; 47: 1853-61.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1853-1861
    • Tam, V.H.1    McKinnon, P.S.2    Akins, R.L.3
  • 13
    • 0034754449 scopus 로고    scopus 로고
    • What in vitro models of infection can and cannot do
    • White RL. What in vitro models of infection can and cannot do. Pharmacotherapy 2001; 21: 292-301S.
    • (2001) Pharmacotherapy , vol.21
    • White, R.L.1
  • 14
    • 40049096742 scopus 로고    scopus 로고
    • Kahlmeter G. EUCAST procedure for harmonizing and defining breakpoints. http://www.srga.org/EUCAST/bpsetting.htm (17 July 2007, date last accessed).
    • Kahlmeter G. EUCAST procedure for harmonizing and defining breakpoints. http://www.srga.org/EUCAST/bpsetting.htm (17 July 2007, date last accessed).
  • 15
    • 0026551574 scopus 로고
    • Pharmacokinetics of cefepime after single and multiple intravenous administrations in healthy subjects
    • Barbhaiya RH, Forgue ST, Gleason CR et al. Pharmacokinetics of cefepime after single and multiple intravenous administrations in healthy subjects. Antimicrob Agents Chemother 1992; 36: 552-7.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 552-557
    • Barbhaiya, R.H.1    Forgue, S.T.2    Gleason, C.R.3
  • 16
    • 0030864108 scopus 로고    scopus 로고
    • Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses
    • Chien SC, Rogge MC, Gisclon LG et al. Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses. Antimicrob Agents Chemother 1997; 41: 2256-60.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2256-2260
    • Chien, S.C.1    Rogge, M.C.2    Gisclon, L.G.3
  • 17
    • 0031956777 scopus 로고    scopus 로고
    • Double-blind evaluation of the safety and pharmacokinetics of multiple oral once-daily 750-milligram and 1-gram doses of levofloxacin in healthy volunteers
    • Chien SC, Wong FA, Fowler CL et al. Double-blind evaluation of the safety and pharmacokinetics of multiple oral once-daily 750-milligram and 1-gram doses of levofloxacin in healthy volunteers. Antimicrob Agents Chemother 1998; 42: 885-8.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 885-888
    • Chien, S.C.1    Wong, F.A.2    Fowler, C.L.3
  • 18
    • 0030896242 scopus 로고    scopus 로고
    • Pharmacokinetics of gentamicin at traditional versus high doses: Implications for once-daily aminoglycoside dosing
    • Demczar DJ, Nafziger AN, Bertino JS, Jr. Pharmacokinetics of gentamicin at traditional versus high doses: Implications for once-daily aminoglycoside dosing. Antimicrob Agents Chemother 1997; 41: 1115-9.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1115-1119
    • Demczar, D.J.1    Nafziger, A.N.2    Bertino Jr., J.S.3
  • 19
    • 0030049979 scopus 로고    scopus 로고
    • Serum bactericidal activities and comparative pharmacokinetics of meropenem and imipenem-cilastatin
    • Dreetz M, Hamacher J, Eller J et al. Serum bactericidal activities and comparative pharmacokinetics of meropenem and imipenem-cilastatin. Antimicrob Agents Chemother 1996; 40: 105-9.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 105-109
    • Dreetz, M.1    Hamacher, J.2    Eller, J.3
  • 20
    • 0023128712 scopus 로고
    • Pharmacokinetics of cefoperazone and tobramycin alone and in combination
    • Guglielmo BJ, Flaherty JF, Woods TM et al. Pharmacokinetics of cefoperazone and tobramycin alone and in combination. Antimicrob Agents Chemother 1987; 31: 264-6.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 264-266
    • Guglielmo, B.J.1    Flaherty, J.F.2    Woods, T.M.3
  • 21
    • 0026692148 scopus 로고
    • Pharmacokinetic profiles of ciprofloxacin after single intravenous and oral doses
    • Lettieri JT, Rogge MC, Kaiser L et al. Pharmacokinetic profiles of ciprofloxacin after single intravenous and oral doses. Antimicrob Agents Chemother 1992; 36: 993-6.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 993-996
    • Lettieri, J.T.1    Rogge, M.C.2    Kaiser, L.3
  • 22
    • 0019768365 scopus 로고
    • Comparative multiple-dose pharmacokinetics of cefotaxime, moxalactam, and ceftazidime
    • Luthy R, Blaser J, Bonetti A et al. Comparative multiple-dose pharmacokinetics of cefotaxime, moxalactam, and ceftazidime. Antimicrob Agents Chemother 1981; 20: 567-75.
    • (1981) Antimicrob Agents Chemother , vol.20 , pp. 567-575
    • Luthy, R.1    Blaser, J.2    Bonetti, A.3
  • 24
    • 0019859160 scopus 로고
    • Pharmacology of ceftizoxime compared with that of cefamandole
    • Neu HC, Srinivasan S. Pharmacology of ceftizoxime compared with that of cefamandole. Antimicrob Agents Chemother 1981; 20: 366-9.
    • (1981) Antimicrob Agents Chemother , vol.20 , pp. 366-369
    • Neu, H.C.1    Srinivasan, S.2
  • 25
    • 0030694701 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of two multiple-dose piperacillin-tazobactam regimens
    • Occhipinti DJ, Pendland SL, Schoonover LL et al. Pharmacokinetics and pharmacodynamics of two multiple-dose piperacillin-tazobactam regimens. Antimicrob Agents Chemother 1997; 41: 2511-7.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2511-2517
    • Occhipinti, D.J.1    Pendland, S.L.2    Schoonover, L.L.3
  • 26
    • 0026658473 scopus 로고
    • Comparative study of pharmacokinetics and serum bactericidal activities of cefpirome; ceftazidime, ceftriaxone, imipenem, and ciprofloxacin
    • Paradis D, Vallee F, Allard S et al. Comparative study of pharmacokinetics and serum bactericidal activities of cefpirome; ceftazidime, ceftriaxone, imipenem, and ciprofloxacin. Antimicrob Agents. Chemother 1992; 36; 2085-92.
    • (1992) Antimicrob Agents. Chemother , vol.36 , pp. 2085-2092
    • Paradis, D.1    Vallee, F.2    Allard, S.3
  • 27
    • 4644351577 scopus 로고    scopus 로고
    • Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers
    • Pletz MW, Rau M, Bulitta J et al. Ertapenem pharmacokinetics and impact on intestinal microflora, in comparison to those of ceftriaxone, after multiple dosing in male and female volunteers. Antimicrob Agents Chemother 2004; 48: 3765-72.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3765-3772
    • Pletz, M.W.1    Rau, M.2    Bulitta, J.3
  • 29
    • 0028227016 scopus 로고
    • Comparative pharmacokinetics and safety of ciprofloxacin 400 mg iv thrice daily versus 750 mg po twice daily
    • Shah A, Lettieri J, Kaiser L et al. Comparative pharmacokinetics and safety of ciprofloxacin 400 mg iv thrice daily versus 750 mg po twice daily. J Antimicrob Chemother 1994; 33: 795-801.
    • (1994) J Antimicrob Chemother , vol.33 , pp. 795-801
    • Shah, A.1    Lettieri, J.2    Kaiser, L.3
  • 30
    • 0031856680 scopus 로고    scopus 로고
    • The pharmacodynamics of β-lactams
    • Turnidge JD. The pharmacodynamics of β-lactams. Clin Infect Dis 1998; 27: 10-22.
    • (1998) Clin Infect Dis , vol.27 , pp. 10-22
    • Turnidge, J.D.1
  • 31
    • 40049098423 scopus 로고    scopus 로고
    • Meropenem Yearly Susceptibility Test Information Collection (MYSTIC). http://www.mystic-data.org (8 January 2007, date last accessed).
    • Meropenem Yearly Susceptibility Test Information Collection (MYSTIC). http://www.mystic-data.org (8 January 2007, date last accessed).
  • 32
    • 34347339333 scopus 로고    scopus 로고
    • Reevaluation of current susceptibility breakpoints for Gram-negative rods based on pharmacodynamic assessment
    • DeRyke CA, Kuti. JL, Nicolau DP. Reevaluation of current susceptibility breakpoints for Gram-negative rods based on pharmacodynamic assessment. Diagn Microbiol Infect Dis 2007; 58: 337-44.
    • (2007) Diagn Microbiol Infect Dis , vol.58 , pp. 337-344
    • DeRyke, C.A.1    Kuti, J.L.2    Nicolau, D.P.3
  • 33
    • 0034812780 scopus 로고    scopus 로고
    • Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections
    • Ambrose PG, Grasela DM, Grasela TH et al. Pharmacodynamics of fluoroquinolones against Streptococcus pneumoniae in patients with community-acquired respiratory tract infections. Antimicrob Agents Chemother 2001; 45: 2793-7.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2793-2797
    • Ambrose, P.G.1    Grasela, D.M.2    Grasela, T.H.3
  • 34
    • 17744378978 scopus 로고    scopus 로고
    • Continuous infusion β-lactams for intensive care unit pulmonary infections
    • Frei CR, Burgess DS. Continuous infusion β-lactams for intensive care unit pulmonary infections. Clin Microbiol Infect 2005; 11: 418-21.
    • (2005) Clin Microbiol Infect , vol.11 , pp. 418-421
    • Frei, C.R.1    Burgess, D.S.2
  • 35
    • 33846442436 scopus 로고    scopus 로고
    • Piperacillin-tazobactam for Pseudomonas aeruginosa infection: Clinical implications of an extended-infusion dosing strategy
    • Lodise TP, Jr,. Lomaestro B, Drusano GL. Piperacillin-tazobactam for Pseudomonas aeruginosa infection: Clinical implications of an extended-infusion dosing strategy. Clin Infect Dis 2007; 44: 357-63.
    • (2007) Clin Infect Dis , vol.44 , pp. 357-363
    • Lodise Jr, T.P.1    Lomaestro, B.2    Drusano, G.L.3
  • 36
    • 21444436000 scopus 로고    scopus 로고
    • Comparison of pharmacodynamic target attainment between healthy subjects and patients for ceftazidime and meropenem
    • Kuti JL, Horowitz S, Nightingale CH et al. Comparison of pharmacodynamic target attainment between healthy subjects and patients for ceftazidime and meropenem. Pharmacotherapy 2005; 25: 935-41.
    • (2005) Pharmacotherapy , vol.25 , pp. 935-941
    • Kuti, J.L.1    Horowitz, S.2    Nightingale, C.H.3
  • 37
    • 40049092441 scopus 로고    scopus 로고
    • To split, or not to split a MIC distribution that is the question: Setting susceptibility breakpoints
    • Chicago, IL, Abstract D-222, p, American Society for Microbiology, Washington, DC, USA
    • Bhavnani SM, Ambrose PG, Jones RN et al. To split, or not to split a MIC distribution that is the question: Setting susceptibility breakpoints. In: Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, 2007 Abstract D-222, p. 153. American Society for Microbiology, Washington, DC, USA.
    • (2007) Abstracts of the Forty-seventh Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 153
    • Bhavnani, S.M.1    Ambrose, P.G.2    Jones, R.N.3
  • 38
    • 0029097440 scopus 로고
    • Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins
    • Craig WA. Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins. Diagn Microbiol Infect Dis 1995; 22: 89-96.
    • (1995) Diagn Microbiol Infect Dis , vol.22 , pp. 89-96
    • Craig, W.A.1
  • 39
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig WA. Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998; 26 1-10
    • (1998) Clin Infect Dis , vol.26 , pp. 1-10
    • Craig, W.A.1
  • 40
    • 0036226940 scopus 로고    scopus 로고
    • Animal model pharmacokinetics and pharmacodynamics: A critical review
    • Andes D, Craig WA. Animal model pharmacokinetics and pharmacodynamics: A critical review. Int J Antimicrob Agents 2002; 19: 261-8.
    • (2002) Int J Antimicrob Agents , vol.19 , pp. 261-268
    • Andes, D.1    Craig, W.A.2
  • 41
    • 0038372082 scopus 로고    scopus 로고
    • Free drug 24 h AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides, and clindamycin
    • San Diego, CA, Abstract A-1264, p, American Society for Microbiology, Washington, DC, USA
    • Craig WA, Kiem S, Andes DR. Free drug 24 h AUC/MIC is the PK/PD target that correlates with in vivo efficacy of macrolides, azalides, ketolides, and clindamycin, In: Abstracts of the Forty-second Interscience Conference on Antimicrobial Agents and Chemotherapy, San Diego, CA, 2002. Abstract A-1264, p. 14. American Society for Microbiology, Washington, DC, USA.
    • (2002) Abstracts of the Forty-second Interscience Conference on Antimicrobial Agents and Chemotherapy , pp. 14
    • Craig, W.A.1    Kiem, S.2    Andes, D.R.3
  • 43
    • 33845696211 scopus 로고    scopus 로고
    • Pharmacokinetics-pharmacodynamics of antimicrobial therapy: It's not just for mice anymore
    • Ambrose PG, Bhavnani SM, Rubino CM et al. Pharmacokinetics-pharmacodynamics of antimicrobial therapy: It's not just for mice anymore. Clin Infect Dis 2007; 44: 79-86.
    • (2007) Clin Infect Dis , vol.44 , pp. 79-86
    • Ambrose, P.G.1    Bhavnani, S.M.2    Rubino, C.M.3
  • 44
    • 0037439449 scopus 로고    scopus 로고
    • Prevention of resistance: A goal for dose selection for antimicrobial agents
    • Drusano. GL. Prevention of resistance: A goal for dose selection for antimicrobial agents. Clin Infect Dis 2003; 36 Suppl 1: S42-50.
    • (2003) Clin Infect Dis , vol.36 , Issue.SUPPL. 1
    • Drusano, G.L.1


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