Vitamin D receptor levels and binding are reduced in aged rat intestinal subcellular fractions

Biogerontology

Volumn 9, Issue 2, 2008, Pages 109-118

  González Pardo, Verónica ^a   Boland, Ricardo ^a   Boland, Ana Russo ^a  

^a UNIVERSIDAD NACIONAL DEL SUR   (Argentina)

Author keywords

1 ,25(OH)2D3; Ageing; Enterocytes; Subcellular fractions; Vitamin D receptor

Indexed keywords

CALCITRIOL; HORMONE RECEPTOR; VITAMIN D RECEPTOR;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING ASSAY; CELL FRACTIONATION; CELL MEMBRANE; CELL NUCLEUS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; IMMUNOFLUORESCENCE TEST; INTESTINE CELL; MALE; MICROSOME; MITOCHONDRION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; RAT; RECEPTOR BINDING; WESTERN BLOTTING;

AGE FACTORS; AGING; ANIMALS; BINDING, COMPETITIVE; BLOTTING, WESTERN; CALCITRIOL; CELL NUCLEUS; CYTOSOL; DOWN-REGULATION; ENTEROCYTES; FLUORESCENT ANTIBODY TECHNIQUE; INTESTINES; MALE; MICROSCOPY, CONFOCAL; MICROSOMES; MITOCHONDRIA; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, CALCITRIOL; SUBCELLULAR FRACTIONS;

EID: 39949085445     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-007-9118-2     Document Type: Article

References (43)

1. Adams JS, Chen H, Gacad M, Encinas C, Ren S, Nguyen L, Wu S, Hewison M, Barsony J (2004) Response element binding proteins and intracellular vitamin D binding proteins: Novel regulators of vitamin D trafficking, action and metabolism. J Steroid Biochem Mol Biol 89-90:461-465
2. Armbrecht HJ, Forte LR, Halloran BP (1984) Effect of age and dietary calcium on renal 25(OH)D metabolism, serum 1,25(OH)2D and PTH. Am J Physiol 245:E266-E270
3. Baker AR, McDonnell DP, Hughes MR, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW (1988) Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci USA 85:3294-3298
4. Barsony J, Renyi I, Mc Koy W (1997) Subcellular distribution of normal and mutan vitamin D receptors in living cells. Studies with a novel fluorescent ligand. J Biol Chem 272:5774-5782
5. Boland R, de Boland AR, Marinissen MJ, Santillan G, Vazquez G, Zanello S. (1995) Avian muscle cells as targets for the secosteroid hormone 1,25-dihydroxy-vitamin D3. Mol Cell Endocrinol 114:1-8
6. Bradford M (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
7. Brumbaugh PF, Haussler MR (1975) Specific binding of 1,25 dihydroxycholecalciferol to nuclear components of chick intestine. J Biol Chem 250:1588-1594
8. 3. Biochem Biophys Res Commun 289:1150-1156
9. 3 receptor cDNA. Proc Natl Acad Sci USA 85(4):1005-1009
10. 3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells. J Biol Chem 264:20265-20274
11. Civitelli R, Kim YS, Gunsten SL, Fujimori A, Huskey M, Avioli LV, Hruska KA (1990) Nongenomic activation of the calcium message system by vitamin D metabolites in osteoblast-like cells. Endocrinology 127:2253-2262
12. 2+ transport in chick perfused duodenum. Biochem Biophys Res Commun 166:217-222
13. Ebeling PR, Sandgren ME, DiMagno EP, Lane AW, DeLuca HF, Riggs BL (1992) Evidence of an age-related decrease in intestinal responsiveness to vitamin D: Relationship between serum 1,25-dihydroxyvitamin D3 and intestinal vitamin D receptor concentrations in normal women J Clin Endocrinol Metab 75:176-182
14. Erben RG, Soegiarto DW, Weber K, Zeitz U, Lieberherr M, Gniadecki R, Möller G, Adamski J, Balling R (2002) Deletion of deoxyribonucleic acid binding domain of vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. Mol Endocrinol 16:1524-1537
15. 3 in normal human keratinocytes. J Invest Dermatol 106:1212-1217
16. 3 in rat intestinal cells: Effect of ageing. Int J Biochem Cell Biol 36:489-504
17. González Pardo V, Facchinetti MM, Curino A, Boland R, Russo de Boland A (2007) Age-related alteration of 1α,25(OH)2-vitamin D3-dependent activation of p38 MAPK in rat intestinal cells. Biogerontology 8:13-24
18. Halloran BP, Portale AA (2005) Vitamin D metabolism and aging. In: Feldman D, Pike JW, Glorieux FH (eds) Vitamin D. Elsevier Academic Press, San Diego, pp 823-838
19. 3 in vivo and in vitro. Mol Endocrinol 18:2660-2671
20. Jurutka PW, Whitfield GK, Hsieh JC, Thompson PD, Haussler CA, Haussler MR (2001) Molecular nature of the Vitamin D receptor and its role in regulation of gene expression. Rev Endocr Metab Disord 2:203-216
21. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
22. Larsson B, Nemere I (2003) Effect of growth and maturation on membrane-initiated actions of 1,25-dihydroxyvitamin D(3). I. Calcium transport, receptor kinetics, and signal transduction in intestine of male chickens. Endocrinology 144:1726-1735
23. Le Mellay V, Grosse B, Lieberherr M (1997) Phospholipase Cβ and membrane action of calcitriol and estradiol. J Biol Chem 272:11902-11907
24. 3 receptor and vitamin D-dependent calcium binding protein in aged Wistar rats. Exp Gerontol 2:179-186
25. Linbäk B, Berlin T, Björkhem I (1987) Three commercial kits and one liquid-chromatographic method evaluated for determining 25-hydroxyvitaminD3 in serum. Clin Chem 33/7:1226-1227
26. Lu Z, Hanson K, DeLuca HF (1967) Cloning and origin of the two forms of chicken vitamin D receptor. Arch Biochem Biophys 339:99-106
27. 3 stimulation of calcium uptake by rat intestinal cells involves a dihydropyridine-sensitive cAMP-dependent pathway. Cell Signal 6:299-304
28. 3 in rat intestinal cells. Endocrinol Metab 2:157-163
29. 3. Endocrinology 115:1476-1483
30. 3 receptors: Gene regulation and genetic circuitry. FASEB J 2:3043-3053
31. 3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia. J Biol Chem 269:23750-23756
32. 3 membrane binding protein (1,25D 3 -MARRS) and phosphate uptake in intestinal cells. PNAS 101:7392-7397
33. NIH (1996) Guide for the care and use of laboratory animals, 7th edn. National Academy Press, Washington, aka National Research Council Guide
34. 3: Past, present, and future. J Bone Miner Res 13:1360-1369
35. 3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways. J Steroid Biochem Mol Biol 41:231-240
36. 3. Trends Endocrinol Metab 9:419-427
37. Slovik DM, Adams JS, Neer RM, Holick MF, Potts JT Jr (1981) Deficient production of 1,25-dihydroxyvitamin D in elderly osteoporotic patients. N Engl J Med 305:372-374
38. Song X, Bishop JE, Okamura WH, Norman AW (1998) Stimulation of phosphorylation of mitogen-activated protein kinase by 1alpha,25-dihydroxyvitamin D3 in promyelocytic NB4 leukemia cells: A structure-function study. Endocrinology 139:457-465
39. 3 receptor in vivo. Proc Natl Acad Sci USA 24:9770-9773
40. 3 receptors in Wistar rats. Biochim Biophys Acta 1034:22-28
41. Wada L, Daly R, Kern D, Halloran B (1992) Kinetics of 1,25-dihydroxyvitamin D metabolism in the aging rat. Am J Physiol 262:E906-E910
42. Wecksler WR, Norman AW (1979) An hydroxylapatite bath assay for the quantification of 1,25-dihydroxyvitamin D3-recetor complexes. Anal Biochem 92:314-323
43. Weiser MM (1973) Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation. J Biol Chem 248(7):2536-2541