Hypothyroidism impairs antioxidant defence system and testicular physiology during development and maturation

General and Comparative Endocrinology

Volumn 156, Issue 1, 2008, Pages 63-70

  Sahoo, Dipak K ^a   Roy, Anita ^a   Bhanja, Shravani ^a   Chainy, Gagan B N ^a  

^a UTKAL UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; Hypothyroidism; Oxidative stress; Rat; Testis

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; PROPYLTHIOURACIL; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARBONYLATION; CELL COUNT; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDIDYMIS; GERM CELL; HYPOTHYROIDISM; LIPID PEROXIDATION; MALE; MATURATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPERM; TESTIS CELL; TESTIS DEVELOPMENT; WEIGHT REDUCTION;

EID: 39649122589     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2007.11.007     Document Type: Article

References (57)

1. Alvarez J.G., and Storey B. Assessment of cell damage caused by spontaneous lipid peroxidation in rabbit spermatozoa. Biol. Reprod. 30 (1984) 323-331
2. Amin S.O., and El-Sheikh A.S. Pituitary-testicular function changes in hypo and hyperthyroid male rats. Acta Anat. 98 (1977) 121-129
3. Asayama K., Dobashi K., Hayashibe H., Megata Y., and Kato K. Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: a possible mechanism of injury to heart and skeletal muscle in hyperthyroidism. Endocrinology 121 (1987) 2112-2118
4. Bauche F., Fouchard M.H., and Jegou B. Antioxidant system in rat testicular cells. FEBS Lett. 349 (1994) 392-396
5. Bunick D., Kirby J., Hess R.A., and Cooke P.S. Development expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism. Biol. Reprod. 51 (1994) 706-713
6. Calvin H.I., and Turner S.I. High levels of glutathione attained during postnatal development of rat testis. J. Exp. Zool. 219 (1982) 389-393
7. Carmagnol F., Sinet P.M., and Jerome H. Selenium-dependent and non-selenium-dependent glutathione peroxidases in human tissue extracts. Biochim. Biophys. Acta 759 (1983) 49-57
8. Chandra R., Aneja R., Rewal C., Konduri R., Das S.K., and Agarwal S. An opium alkaloid-Papaverine ameliorates ethanol-induced hepatotoxicity: diminution of oxidative stress. Ind. J. Clin. Biochem. 15 (2000) 155-160
9. Chattopadhyay S., Sahoo D.K., Subudhi U., and Chainy G.B.N. Differential expression profiles of antioxidant enzymes and glutathione redox status in hyperthyroid rats: a temporal analysis. Comp. Biochem. Physiol. C146 (2007) 383-391
10. Chiao Y.C., Cho W.L., and Wang P.S. Inhibition of testosterone production by propylthiouracil in rat Leydig cells. Biol. Reprod. 67 (2002) 416-422
11. Chiao Y.C., Lin H., Wang S.W., and Wang P.S. Direct effects of propylthiouracil on testosterone secretion in rat testicular interstitial cells. Br. J. Pharmacol. 130 (2000) 1477-1482
12. Choudhury S., Chainy G.B.N., and Mishro M.M. Experimentally induced hypo- and hyperthyroidism influence on the antioxidant defence system in adult rat testis. Andrologia 35 (2003) 131-140
13. Cohen G., Dembiec D., and Marcus J. Measurement of catalase activity in tissue extracts. Anal. Biochem. 34 (1970) 30-38
14. Cooke P.S., and Meisami E. Early hypothyroidism in rat causes increased adult testis and reproductive organ size but does not change testosterone levels. Endocrinology 129 (1991) 237-243
15. Das K., Samanta L., and Chainy G.B.N. A modified spectrophotometric assay of superoxide dismutase using nitrite formation of superoxide radicals. Indian J. Biochem. Biophys. 37 (2000) 201-204
16. Das K., and Chainy G.B.N. Thyroid hormone influences antioxidant defence in adult rat brain. Neurochem. Res. 29 (2004) 1755-1766
17. De Franca L.R., Hess R.A., Cooke P.S., and Russel L.D. Neonatal hypothyroidism causes delayed Sertoli cell maturation in rats treated with propylthiouracil: evidence that the Sertoli cell controls testis growth. Anat. Rec. 242 (1995) 57-69
18. Del Rio A.G., Palaoro L.A., Blanco A.M., and Niepomniszcze H. Epididymal scanning electron microscopy study in hypothyroid rats. Arch. Androl. 46 (2001) 73-77
19. Fernandez V., and Videla L.A. Hepatic glutathione biosynthetic capacity in hyperthyroid rats. Toxicol. Lett. 89 (1996) 85-89
20. Francavilla S., Cordeschi G., Properzi G., Di Cicco L., Jannini E.A., Palmero S., Fugassa E., Loras B., and D'Amiento M. Effect of thyroid hormone on the pre- and post-natal development of the rat testis. J. Endocrinol. 129 (1991) 35-42
21. Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106 (1980) 207-212
22. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
23. Halliwell, B., Gutteridge, J.M.C., 2001. In: Free Radicals in Biology and Medicine, third ed. Oxford University Press, New York.
24. Hardy M.P., Kirby J.D., Hess R.A., and Cooke P.S. Leydig cells increase their numbers but decline in steroidogenic function in the adult rat after neonatal hypothyroidism. Endocrinology 132 (1993) 2417-2420
25. Hoch F.L. Lipids and thyroid hormones. Prog. Lipid Res. 27 (1988) 199-270
26. Holsberger D.R., and Cooke P.S. Understanding the role of thyroid hormone in Sertoli cell development: a mechanistic hypothesis. Cell Tissue Res. 322 (2005) 133-140
27. Jannini E.A., Ulisse S., and d'Armiento M. Thyroid hormone and male gonadal function. Endocr. Rev. 16 (1995) 443-459
28. Jubiz, W., 1987. The testes. In: Endocrinology: A Logical Approach for Clinicians, second ed. Mc Graw-Hill Book Co., Singapore, pp. 387-408.
29. Knapen M.F.C.M., Zusterzeel P.L.M., Peters W.H.M., and Steegers E.A.P. Glutathione and glutathione-related enzymes in reproduction. A review. Eur. J. Obstet. Gynecol. Reprod. Biol. 82 (1999) 171-184
30. Lee C.Y. Glucose-6-phosphate dehydrogenase from mouse. Methods Enzymol. 89 (1982) 252-257
31. Levine R.L., Garland D., Oliver C.N., Amici A., Climent I., Lenz A.G., Ahn B.W., Shaltiel S., and Stadtman E.R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186 (1990) 464-478
32. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193 (1951) 265-275
33. Maran R.R.M. Thyroid hormones: their role in testicular steroidogenesis. Arch. Androl. 49 (2003) 375-388
34. Maran R.R.M., Ravichandran K., Arunakaran J., and Aruldhas M.M. Impact of neonatal hypothyroidism on Leydig cell number, plasma, and testicular interstitial fluid sex steroids concentration. Endocr. Res. 27 (2001) 119-141
35. Maran R.R.M., Sivakumar R., Arunakaran J., Ravisankar B., Ravichandran K., Sidharthan V., Jeyaraja D.A., and Aruldhas M.M. Duration-dependent effect of transient neonatal hypothyroidism on Sertoli and germ cell number, and plasma and testicular interstitial fluid androgen binding protein concentration. Endocr. Res. 25 (1999) 323-340
36. Massey V., and Williams Jr. C.H. On the reaction mechanism of yeast glutathione reductase. J. Biol. Chem. 240 (1965) 4470-4480
37. Meisami E., Najafi A., and Timiras P.S. Enhancement of seminiferous tubular growth and spermatogenesis in testes of rats recovering from early hypothyroidism: a quantitative study. Cell Tissue Res. 275 (1994) 503-511
38. Mendis-Handagama S.M.L.C., Ariayaratne H.B.S., Teunissen van Manen K.R., and Haupt R.L. Differentiation of adult Leydig cells in the neonatal rat testis is arrested by hypothyroidism. Biol. Reprod. 59 (1998) 351-357
39. Mogulkoc R., Baltaci A.K., Oztekin E., Ozturk A., and Sivrikaya A. Short term thyroxine administration leads to lipid peroxidation in renal and testicular tissues of rats with hypothyroidism. Acta Biol. Hung. 56 (2005) 225-232
40. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal. Biochem. 95 (1979) 351-358
41. Paglia D.E., and Valentine W.N. Studies on quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70 (1967) 158-169
42. Palmero S., Prati M., De Marco P., Trucchi P., and Fugassa E. Thyroid regulation of nuclear tri-iodothyronine receptors in the developing rat testis. J. Endocrinol. 136 (1993) 277-282
43. Rao J.N., Liang J.Y., Chakraborti P., and Feng P. Effect of thyroid hormone on the development and gene expression of hormone receptors in rat testis in vivo. J. Endocrinol. Invest. 26 (2003) 435-443
44. Sahoo D.K., Roy A., and Chainy G.B.N. PTU-induced neonatal hypothyroidism modulates antioxidative status and population of rat testicular germ cells. Natl. Acad. Sci. Lett. 29 (2006) 133-135
45. Sahoo D.K., Roy A., Bhanja S., and Chainy G.B.N. Experimental hyperthyroidism-induced oxidative stress and impairment of antioxidant defence system in rat testis. Ind. J. Exp. Biol. 43 (2005) 1058-1067
46. 3 treatment on glutathione redox pool and its metabolizing enzymes in mitochondrial and post-mitochondrial fractions of adult rat testes. Ind. J. Exp. Biol. 45 (2007) 338-346
47. Sahoo D.K., and Chainy G.B.N. Tissue specific response of antioxidant defence systems of rat to experimentally-induced hyperthyroidism. Natl. Acad. Sci. Lett. 30 (2007) 247-250
48. Sharpe R.M., Bartlett J.M., and Allenby G. Evidence for the control of testicular interstitial fluid volume in the rat by specific germ cell types. J. Endocrinol. 128 (1991) 359-367
49. Sharpe R.M., and Cooper I. Testicular interstitial fluid as a monitor for changes in the intratesticular environment in the rat. J. Reprod. Fert. 69 (1983) 125-135
50. Sharpe R.M., McKinnell C., Kivlin C., and Fisher J.S. Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood. Reproduction. 125 (2003) 769-784
51. Sies H. Thiolgruppen: Bedeutung des Glutathiones. Naturwissenschaflin. Zur. Biochemie der. 76 (1989) 57-64
52. Simorangkir D.R., Wreford N.G., and De Kretser D.M. Impaired germ cell development in the testes of immature rats with neonatal hypothyroidism. J. Androl. 18 (1997) 186-193
53. Tahmaz L., Gokalp A., Kibar Y., Kocak I., Yalcin O., and Ozercan Y. Effect of hypothyroidism on the testes in mature rats and treatment with levothyroxine and zinc. Andrologia 32 (2000) 85-89
54. Teaf C.M., Harbison R.D., and Bishop J.B. Germ-cell mutagenesis and GSH depression in reproductive tissue of the F-344 rat induced by ethyl methanesulfonate. Mut. Res. 144 (1985) 93-98
55. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione; applications to mammalian blood and other tissue. Anal. Biochem. 27 (1969) 502-522
56. Van Haaster L.H., De Jong F.H., Docter R., and De Rooij D.G. The effect of hypothyroidism on Sertoli cell proliferation and differentiation and hormone levels during testicular development in the rat. Endocrinology 131 (1992) 1574-1576
57. Venditti P., Balestrieri M., Di Meo S., and De Leo T. Effect of thyroid state on lipid peroxidation, antioxidant defences and susceptibility to oxidative stress in rat tissues. J. Endocrinol. 155 (1997) 151-157