Short-term thyroxine administration leads to lipid peroxidation in renal and testicular tissues of rats with hypothyroidism

Acta Biologica Hungarica

Volumn 56, Issue 3-4, 2005, Pages 225-232

  Mogulkoc, R ^a   Baltaci, A K ^a   Oztekin, E ^a   Ozturk, A ^a   Sivrikaya, A ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Hypothyroidism; Oxidant stress; Rat; Thyroxine administration

Indexed keywords

ANTITHYROID AGENT; GLUTATHIONE; MALONALDEHYDE; PROPYLTHIOURACIL; THYROXINE;

ANIMAL; ARTICLE; HYPOTHYROIDISM; KIDNEY; LIPID PEROXIDATION; MALE; METABOLISM; OXIDATIVE STRESS; RAT; SPRAGUE DAWLEY RAT; TESTIS;

ANIMALS; ANTITHYROID AGENTS; GLUTATHIONE; HYPOTHYROIDISM; KIDNEY; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; OXIDATIVE STRESS; PROPYLTHIOURACIL; RATS; RATS, SPRAGUE-DAWLEY; TESTIS; THYROXINE;

ANIMALIA;

EID: 24144501558     PISSN: 02365383     EISSN: None     Source Type: Journal    
DOI: 10.1556/ABiol.56.2005.3-4.6     Document Type: Article

References (31)

1. Amer, M. A. (2002) Modulation of age-related biochemical changes and oxidative stress by vitamin C and glutathione supplementation in old rats. Ann. Nutr. Metab. 46, 165-168.
2. Asayama, K., Dobashi, K., Hayashibe, H., Megata, Y., Kato, K. (1987) Lipid peroxidation and free radical scavengers in thyroid dysfunction in the rat: a possible mechanism of injury to heart and skeletal muscle in hyperthyroidism. Endocrinology 121, 2112-2118.
3. Asayama, K., Kato, K. (1990) Oxidative muscular injury and its relevance to hyperthyroidism. Free Radic. Biol. Med. 8, 293-303.
4. Berzinska-Slebodzinska, E. (2001) Fever induced oxidative stress: the effect of thyroid status and the 5′-monodeiodinase activity, protective role of selenium and vitamin E. J. Physiol. Pharmacol. 52, 275-284.
5. Choudhury, S., Chainy, G. B. N., Mishro, M. M. (2003) Experimentally induced hypo- and hyperthyroidism influence on the antioxidant defence system in adult rat testis. Andrologia 35, 131-140.
6. Droge, W. (2002) Free radicals in physiological control of cell function. Physiol. Rev. 82, 47-95.
7. Elman, G. L. (1959) Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82, 70-77.
8. Faure, M., Lissi, E. A., Videla, L. A. (1991) Evaluation of the antioxidant properties of thyroid hormones and propylthiouracil in the brain-homogenate autoxidation system and in the free radical-mediated oxidation of erythrocyte membranes. Chem. Biol. Interact. 77, 173-85.
9. Fernandez, V., Barrientos, X., Kipreos, K., Valenzuela, A., Videla, L. A. (1985) Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state: relation to lipid peroxidation. Endocrinology 117, 496-501.
10. Fernández, V., Llesuy, S., Solari, L., Kipreos, K., Videla, L. A. (1998) Boveris A. Chemiluminescent and respiratory responses related to thyroid hormone-induced liver oxidative stress. Free Radic. Res. Commun. 5, 77-84.
11. Galkina, V., Prokopenko, V. M., Putilina, F. E., Eshchenko, N. D., Arutyunyan, A. V. (2001) The effects of thyroxine isomers on free-radical oxidation processes in subcellular fractions of rat cerebral cortex. Neurosci. Behav. Physiol. 31, 463-465.
12. Goglia, F., Silvetri, E., Lanni, A. (2002) Thyroid hormones and mitocondria. Biosci. Rep. 22, 17-32.
13. Gredilla, R., Lopez-Torres, M., Portero-Otin, M., Pamplona, R., Barja, G. (2001) Influence of hyper- and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice skeletal muscle. Mol. Cell Biochem. 221, 41-48.
14. Karbownik, M., Lewinski, A. (2003) The role of oxidative stress in physiological and pathological processes in the thyroid gland; possible involvement in pineal-thyroid interactions. Neuroendocrinol. Lett. 24, 293-303.
15. Katzeff, H. L., Powell, S. R., Ojamaa, K. (1997) Alterations in cardiac contractility and gene expression during low-T3 syndrome: prevention with T3. Am. J. Physiol. 273, E951-E956.
16. Kobori, H., Ichihara, A., Miyashita, Y., Hayashi, M., Saruta, T. (1998) Mechanism of hyperthyroidism-induced renal hypertrophy in rats. J. Endocrinol. 159, 9-14.
17. Lopez-Torres, M., Romero, M., Barja, G. (2000) Effect of thyroid hormones on mitochondrial oxygen freee radical production and DNA oxidative damage in the rat heart. Mol. Cell. Endocrinol. 168, 127-134.
18. Mano, T., Sinohara, R., Sawai, Y., Oda, N., Nishida, Y., Mokumo, T., Asano, K., Ito, Y., Kotake, M., Hamada, M. (1995) Changes in lipid peroxidation and free radical scavengers in the brain of hyper-and hypothyroid aged rats. J. Endocrinology 147, 361-365.
19. Mogulkoc, R., Canpolat, L., Baltaci, A. K., Yilmaz, B., Kelestimur, H. (1999) Histological examination of various tissues in propylthiouracil and thyroidectomy-induced hypothyroidism in the rat. Med. Sci. Res. 27, 801-805.
20. Oziol, L., Faure, P., Vergely, C., Rochette, L., Artur, Y., Chomard, P., Chomard, P. (2001) In vitro free radical scavenging capacity of thyroid hormones and structural analogues. J. Endocrinol. 170, 197-206.
21. Paller, M. S. (1986) Hypothyroidism protects against free radical damage in ischemic acute renal failure. Kidney Int. 29, 1162-1166.
22. Rahaman, S. O., Ghosh, S., Mohanakumar, K. P., Das, S., Sarkar, P. K. (2001) Hypothyroidism in the developing rat brain is associated with marked oxidative stress and aberrant intraneuronal accumulation of neurofilaments. Neurosci. Res. 40, 273-279.
23. Ross, A. D., Varghese, G., Oporto, B., Carmichael, F. J., Israel, Y. (1995) Effect of propylthiouracil treatment on NADPH-cytochrome P450 reductase levels, oxygen consumption and hydroxyl radical formation in liver microsomes from rats fed ethanol or acetone chronically. Biochem. Pharmacol. 49, 979-989.
24. Sewerynek, E., Wiktorska, J., Lewinski, A. (1999) Effects of melatonin on the oxidative stress induced by thyrotoxicosis in rats. Neuroendocrinol. Lett. 20, 157-161.
25. Shinohara, R., Mano, T., Nagasaka, A., Hayashi, R., Uchimura, K., Nakano, I., Watanabe, F., Tsugawa, T., Makino, M., Kakizawa, H., Nagata, M., Iwase, K., Ishizuki, Y., Itoh, M. (2000) Lipid peroxidation levels in rat cardiac muscle are affected by age and thyroid status. J. Endocrinol. 164, 97-102.
26. Tapia, G., Cornejo, P., Fernandez, V., Videla, L. A. (1999) Protein oxidation in thyroid hormone-induced liver oxidative stress: relation to lipid peroxidation. Toxicol. Lett. 106, 209-214.
27. Tsai, L. Y., Lee, K. T., Tsai, S. M., Lee, S. C., Yu, H. S. (1993) Changes of lipid peroxide levels in blood and liver tissue of patients with obstructive jaundice. Clin. Chim. Acta 215, 41-50.
28. Uchiyama, M., Mihara, M. (1977) Determination of malondyaldehyde precurser in tissues by thiobarbituric acid test. Anal. Biochem. 86, 271-278.
29. Venditti, P., Balestrieri, M., Di, Meo, S., De Leo, T. (1997) Effect of thyroid state on lipid peroxidation, antioxidant defences, and susceptibility to oxidative stress in rat tissues. J. Endocrinol. 155, 151-157.
30. Venditti, P., De Rosa, R., Di Meo, S. (2003) Effect of thyroid state on susceptibility to oxidants and swelling of mitochondria from rat tissues. Free Radic. Biol. Med. 35, 485-494.
31. Venditti, P., De Rosa, R., Di Meo, S. (2002) Effect of thyroid state on susceptibility to oxidants and swelling of mitocondria from rat tissues. Cardiovasc. Res. 56, 76-85.