Insertion of an intracisternal A particle retrotransposon element in plasma membrane calcium ATPase 2 gene attenuates its expression and produces an ataxic phenotype in joggle mutant mice

Gene

Volumn 411, Issue 1-2, 2008, Pages 94-102

  Sun, Xiao yang ^a   Chen, Zi yan ^a   Hayashi, Yoshitaka ^a   Kanou, Yasuhiko ^a   Takagishi, Yoshiko ^a   Oda, Sen ichi ^a   Murata, Yoshiharu ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Inherited ataxia; Long terminal repeat; Mus musculus molossinus; Nonsense mediated mRNA decay; Positional cloning

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ADENOSINE TRIPHOSPHATASE (CALCIUM) 2; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; CONTROLLED STUDY; GENE; GENE INSERTION; JOGGLE MOUSE; LONG TERMINAL REPEAT; MISSENSE MUTATION; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PMCA2 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROPOSON;

ANIMALS; ATAXIA; BRAIN; CHROMOSOME MAPPING; GENE EXPRESSION; GENES, INTRACISTERNAL A-PARTICLE; MICE; MICE, MUTANT STRAINS; MUTAGENESIS, INSERTIONAL; PHENOTYPE; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; RETROELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

INTRACISTERNAL A-PARTICLES; MUS; MUS MUSCULUS MOLOSSINUS;

EID: 39649107955     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2008.01.013     Document Type: Article

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