Sequencing, bioinformatic characterization and expression pattern of a putative amino acid transporter from the parasitic cestode Echinococcus granulosus

Gene

Volumn 411, Issue 1-2, 2008, Pages 1-9

  Camicia, Federico ^a   Paredes, Rodolfo ^b,c   Chalar, Cora ^d   Galanti, Norbel ^b   Kamenetzky, Laura ^a   Gutierrez, Ariana ^a   Rosenzvit, Mara C ^a  

^a INSTITUTO NACIONAL DE ENFERMEDADES INFECCIOSAS   (Argentina)

^b UNIVERSITY OF CHILE   (Chile)

^c UNIVERSIDAD ANDRÉS BELLO   (Chile)

^d Facultad de Ciencias   (Uruguay)

Author keywords

ASCT; Cystic echinococcosis; DAACS; EgAT1; Helminth parasites

Indexed keywords

AMINO ACID TRANSPORTER; COMPLEMENTARY DNA; MESSENGER RNA; PROTEIN EGAT1; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ARTICLE; BIOINFORMATICS; CONSENSUS SEQUENCE; DNA LIBRARY; DNA SEQUENCE; ECHINOCOCCUS GRANULOSUS; IN SITU HYBRIDIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACID TRANSPORT SYSTEMS; ANIMALS; COMPUTATIONAL BIOLOGY; ECHINOCOCCUS GRANULOSUS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA;

CESTODA; ECHINOCOCCUS GRANULOSUS; VERMES;

EID: 39649099344     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.11.023     Document Type: Article

References (33)

1. Allen J.T., and Arme C. Membrane transport of amino acid enantiomers in protoscoleces of Echinococcus granulosus (Cestoda). Ann. Trop. Med. Parasitol. 85 (1991) 75-82
2. Brownlee D.J.A., Fairweather I., Johnston C.F., and Rogan M.T. Immunocytochemical localization of serotonin (5-HT) in the nervous system of the hydatid organism, Echinococcus granulosus (Cestoda, Cyclophyllidea). Parasitology 109 (1994) 233-241
3. Çelik C., Amanvermez R., and Özkan K. Free amino acid concentration in hydatid cyst fluids from fertile and infertile human and animal Echinococcus granulosus. Parasite 8 (2001) 343-348
4. Chen H., and Leder P. A new signal sequence trap using alkaline phosphatase as a reporter. Nucleic Acids Res. 27 (1999) 1219-1222
5. Donly B.C., Richman A., Hawkins E., McLean H., and Caveney S. Molecular cloning and functional expression of an insect high-affinity Na+-dependent glutamate transporter. Eur. J. Biochem. 248 (1997) 535-542
6. Freire T., et al. Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosus. Biochem. J. 382 (2004) 501-510
7. Gegelashvili G., and Schousboe A. High Affinity glutamate transporters: regulation of expression and activity. Mol. Pharmacol. 52 (1997) 6-15
8. +- and Cl-coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. J. Pharmacol. Exp. Ther. 308 (2004) 1138-1147
9. Hurd H. Echinococcus granulosus: a comparison of free amino acid concentration in hydatid fluid from primary and secondary cyst and host plasma. Parasitology 98 (1989) 135-143
10. Jansson T. Amino acid transporters in the human placenta. Pediatr. Res. 49 (2001) 141-147
11. Jeffs S.A., and Arme C. Echinococcus granulosus: specificity of amino acid transport systems in protoscoleces. Parasitology 95 (1987) 71-78
12. Jeffs S.A., and Arme C. Echinococcus granulosus (Cestoda): uptake of L-amino acids by secondary hydatid cysts. Parasitology 96 (1988) 145-156
13. Kanai T., and Hediger M.A. Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360 (1992) 467-471
14. Kawano T., Takuwa K., and Nakajima T. Structure and activity of a new form of the glutamate transporter of the nematode Caenorhabditis elegans. Biosci. Biotechnol. Biochem. 61 (1997) 927-929
15. Keenan L., and Koopowitz L. Physiology and in situ identification of putative aminergic neurotransmitters in the nervous system of Gyrocotyle fimbriata, a parasitic flatworm. J. Neurobiol. 13 (1982) 9-21
16. Kozak M. An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15 (1987) 8125-8148
17. Lolkema J.S., and Slotboom D.-J. Estimation of structural similarity of membrane proteins by hydropathy profile alignment. Mol. Membr. Biol. 15 (1998) 33-42
18. Lolkema J.S., and Slotboom D.-J. Sequence and hydropathy profile analysis of two classes of secondary transporters. Mol. Membr. Parasitol. 22 (2005) 177-189
19. McManus D.P., and Barret N.J. Isolation, fractionation and partial characterization of the tegumental surface from protoscoleces of the hydatid organism, Echinococcus granulosus. Parasitology 90 (1985) 111-129
20. Mendonça-Silva D.L., Fittipaldi Pessoa R., and Noël F. Evidence for the presence of glutamatergic receptors in adult Schistosoma mansoni. Biochem. Pharmacol. 64 (2002) 1337-1344
21. Miller C.L., Day T.A., Bennett J.L., and Pax R.A. Schistosoma mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter. Exp. Parasitol. 84 (1996) 410-419
22. Pappas P.W., and Read C.P. Membrane transport in helminth parasites: a review. Exp. Parasitol. 37 (1975) 469-530
23. Pow D.V., Sullivan R., and Scott H. Antibody production and immunocytochemical localization of amino acid transporters. In: Yan Q. (Ed). Membrane Transporters: Methods and Protocols. Methods in Molecular Biology 227 (2003), Humana Press Inc., Totowa, NJ 213-244
24. Rosenzvit M.C., et al. Identification of membrane-bound and secreted proteins from Echinococcus granulosus by signal sequence trap. Int. J. Parasitol. 36 (2006) 123-130
25. Saier Jr. M.H. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol. Mol. Biol. Rev. 64 (2000) 354-411
26. +/glutamate cotransporters. J. Biol. Chem. 268 (1993) 15351-15355
27. Slotboom D.J., Konnings W.N., and Lolkema J.S. Structural features of the glutamate transporter family. Microbiol. Mol. Biol. Rev. 63 (1999) 293-307
28. Trotti D., et al. Amyotrophic lateral sclerosis-linked glutamate transporter mutant has impaired glutamate clearance capacity. J. Biol. Chem. 276 (2001) 576-582
29. +-dependent neutral amino acid transporter. J. Biol. Chem. 271 (1996) 14883-14890
30. Wack M., Komuniecki R., and Roberts L.S. Amino acid metabolism in the rat tapeworm, Hymenolepis diminuta. Comp. Biochem. Physiol. 74B (1983) 399-402
31. 3H]glutamate and endogenous glutamate from tissue slices of the cestode Hymenolepis diminuta. Can. J. Physiol. Pharm. 66 (1987) 889-894
32. Yamamoto T., et al. Functional identification of ASCT1 neutral amino acid transporter as predominant system for the uptake of L-serine in rat neurons in primary cultures. Neurosci. Res. 49 (2004) 101-111
33. Yernool D., Boudker O., Jin Y., and Gouaux E. Structure of a glutamate transporter homologue from Pyrococcus horikoshii. Nature 431 (2004) 811-818