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Volumn 284, Issue 1-2, 2008, Pages 21-27

Somatic mutations in the RET proto-oncogene in sporadic medullary thyroid carcinomas

Author keywords

Genetics; Medullary thyroid carcinoma; Prognosis; RET proto oncogene; Somatic mutation

Indexed keywords

ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CZECH REPUBLIC; EXON; FEMALE; GENE DELETION; GENOTYPE PHENOTYPE CORRELATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; ONCOGENE RET; PRIORITY JOURNAL; PROGNOSIS; PROTO ONCOGENE; SOMATIC MUTATION; THYROID MEDULLARY CARCINOMA;

EID: 39649096941     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2007.12.016     Document Type: Article
Times cited : (95)

References (46)
  • 1
    • 0030920032 scopus 로고    scopus 로고
    • A complex nine base pair deletion in RET exon 11 common in sporadic medullary thyroid carcinoma
    • Alemi M., Lucas S.D., Sallstrom J.F., Bergholm U., Akerstrom G., and Wilander E. A complex nine base pair deletion in RET exon 11 common in sporadic medullary thyroid carcinoma. Oncogene 14 (1997) 2041-2045
    • (1997) Oncogene , vol.14 , pp. 2041-2045
    • Alemi, M.1    Lucas, S.D.2    Sallstrom, J.F.3    Bergholm, U.4    Akerstrom, G.5    Wilander, E.6
  • 2
    • 0032960638 scopus 로고    scopus 로고
    • No correlation between RET immunostaining and the codon 918 mutation in sporadic medullary thyroid carcinoma
    • Bockhorn M., Frilling A., Kalinin V., Schröder S., and Broelsch C.E. No correlation between RET immunostaining and the codon 918 mutation in sporadic medullary thyroid carcinoma. Langenbecks Arch. Surg. 384 (1999) 60-64
    • (1999) Langenbecks Arch. Surg. , vol.384 , pp. 60-64
    • Bockhorn, M.1    Frilling, A.2    Kalinin, V.3    Schröder, S.4    Broelsch, C.E.5
  • 3
    • 0033607023 scopus 로고    scopus 로고
    • The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein
    • Bongarzone I., Vigano E., Alberti L., Mondellini P., Uggeri M., Pasini B., Borrello M.G., and Pierotti M.A. The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein. Oncogene 18 (1999) 4833-4838
    • (1999) Oncogene , vol.18 , pp. 4833-4838
    • Bongarzone, I.1    Vigano, E.2    Alberti, L.3    Mondellini, P.4    Uggeri, M.5    Pasini, B.6    Borrello, M.G.7    Pierotti, M.A.8
  • 4
    • 0030988160 scopus 로고    scopus 로고
    • Molecular analysis of the RET proto-oncogene in patients with sporadic medullary thyroid carcinoma: a novel point mutation in the extracellular cysteine-rich domain
    • Bugalho M.J., Frade J.P., Santos J.R., Limbert E., and Sobrinho L. Molecular analysis of the RET proto-oncogene in patients with sporadic medullary thyroid carcinoma: a novel point mutation in the extracellular cysteine-rich domain. Eur. J. Endocrinol. 136 (1997) 423-426
    • (1997) Eur. J. Endocrinol. , vol.136 , pp. 423-426
    • Bugalho, M.J.1    Frade, J.P.2    Santos, J.R.3    Limbert, E.4    Sobrinho, L.5
  • 5
    • 11244327801 scopus 로고    scopus 로고
    • Identification of RET kinase inhibitors as potential new treatment for sporadic and inherited thyroid cancer
    • Carlomagno F., and Santoro M. Identification of RET kinase inhibitors as potential new treatment for sporadic and inherited thyroid cancer. J. Chemother. 16 (2004) 49-51
    • (2004) J. Chemother. , vol.16 , pp. 49-51
    • Carlomagno, F.1    Santoro, M.2
  • 8
    • 0036919703 scopus 로고    scopus 로고
    • Inhibition of medullary thyroid carcinoma cell proliferation and RET phosphorylation by tyrosine kinase inhibitors
    • Cohen M.S., Hussain H.B., and Moley J.F. Inhibition of medullary thyroid carcinoma cell proliferation and RET phosphorylation by tyrosine kinase inhibitors. Surgery 132 (2002) 960-966
    • (2002) Surgery , vol.132 , pp. 960-966
    • Cohen, M.S.1    Hussain, H.B.2    Moley, J.F.3
  • 9
    • 26844496309 scopus 로고    scopus 로고
    • RET polymorphisms and sporadic medullary thyroid carcinoma in a Portuguese population
    • Costa P., Domingues R., Sobrinho L.G., and Bugalho M.J. RET polymorphisms and sporadic medullary thyroid carcinoma in a Portuguese population. Endocrine 27 (2005) 239-243
    • (2005) Endocrine , vol.27 , pp. 239-243
    • Costa, P.1    Domingues, R.2    Sobrinho, L.G.3    Bugalho, M.J.4
  • 12
    • 33645525634 scopus 로고    scopus 로고
    • New multiple somatic mutations in the RET proto-oncogene associated with a sporadic medullary thyroid carcinoma
    • Dvorakova S., Vaclavikova E., Sykorova V., Duskova J., Vlcek P., Ryska A., Novak Z., and Bendlova B. New multiple somatic mutations in the RET proto-oncogene associated with a sporadic medullary thyroid carcinoma. Thyroid 16 (2006) 311-316
    • (2006) Thyroid , vol.16 , pp. 311-316
    • Dvorakova, S.1    Vaclavikova, E.2    Sykorova, V.3    Duskova, J.4    Vlcek, P.5    Ryska, A.6    Novak, Z.7    Bendlova, B.8
  • 13
    • 3242694881 scopus 로고    scopus 로고
    • RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population
    • Elisei R., Cosci B., Romei C., Bottici V., Sculli M., Lari R., Barale R., Pacini F., and Pinchera A. RET exon 11 (G691S) polymorphism is significantly more frequent in sporadic medullary thyroid carcinoma than in the general population. J. Clin. Endocrinol. Metab. 89 (2004) 3579-3584
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 3579-3584
    • Elisei, R.1    Cosci, B.2    Romei, C.3    Bottici, V.4    Sculli, M.5    Lari, R.6    Barale, R.7    Pacini, F.8    Pinchera, A.9
  • 18
    • 0035374716 scopus 로고    scopus 로고
    • CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome
    • Frisk T., Zedenius J., Lundberg J., Wallin G., Kytölä S., and Larsson C. CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome. Int. J. Oncol. 18 (2001) 1219-1225
    • (2001) Int. J. Oncol. , vol.18 , pp. 1219-1225
    • Frisk, T.1    Zedenius, J.2    Lundberg, J.3    Wallin, G.4    Kytölä, S.5    Larsson, C.6
  • 19
    • 0035912105 scopus 로고    scopus 로고
    • Over-representation of a germline variant in the gene encoding RET co-receptor GFRalpha-1 but not GFRalpha-2 or GFRalpha-3 in cases with sporadic medullary thyroid carcinoma
    • Gimm O., Dziema H., Brown J., Hoang-Vu C., Hinze R., Dralle H., Mulligan L.M., and Eng C. Over-representation of a germline variant in the gene encoding RET co-receptor GFRalpha-1 but not GFRalpha-2 or GFRalpha-3 in cases with sporadic medullary thyroid carcinoma. Oncogene 20 (2001) 2161-2170
    • (2001) Oncogene , vol.20 , pp. 2161-2170
    • Gimm, O.1    Dziema, H.2    Brown, J.3    Hoang-Vu, C.4    Hinze, R.5    Dralle, H.6    Mulligan, L.M.7    Eng, C.8
  • 20
    • 0035314012 scopus 로고    scopus 로고
    • Mutation analysis of NTRK2 and NTRK3, encoding 2 tyrosine kinase receptors, in sporadic human medullary thyroid carcinoma reveals novel sequence variants
    • Gimm O., Dziema H., Brown J., de la Punte A., Hoang-Vu C., Dralle H., Plass C., and Eng C. Mutation analysis of NTRK2 and NTRK3, encoding 2 tyrosine kinase receptors, in sporadic human medullary thyroid carcinoma reveals novel sequence variants. Int. J. Cancer 92 (2001) 70-74
    • (2001) Int. J. Cancer , vol.92 , pp. 70-74
    • Gimm, O.1    Dziema, H.2    Brown, J.3    de la Punte, A.4    Hoang-Vu, C.5    Dralle, H.6    Plass, C.7    Eng, C.8
  • 24
    • 0029930893 scopus 로고    scopus 로고
    • RET mutation screening in MEN2 patients and discovery of a novel mutation in a sporadic medullary thyroid carcinoma
    • Jhiang S.M., Fithian L., Weghorst C.M., Clark O.H., Falko J.M., O'Dorisio T.M., and Mazzaferri E.L. RET mutation screening in MEN2 patients and discovery of a novel mutation in a sporadic medullary thyroid carcinoma. Thyroid 6 (1996) 115-121
    • (1996) Thyroid , vol.6 , pp. 115-121
    • Jhiang, S.M.1    Fithian, L.2    Weghorst, C.M.3    Clark, O.H.4    Falko, J.M.5    O'Dorisio, T.M.6    Mazzaferri, E.L.7
  • 25
    • 0347986574 scopus 로고    scopus 로고
    • The newly detected mutations in the RET proto-oncogene in exon 16 as a cause of sporadic medullary thyroid carcinoma
    • Jindrichova S., Kodet R., Krskova L., Vlcek P., and Bendlova B. The newly detected mutations in the RET proto-oncogene in exon 16 as a cause of sporadic medullary thyroid carcinoma. J. Mol. Med. 81 (2003) 819-823
    • (2003) J. Mol. Med. , vol.81 , pp. 819-823
    • Jindrichova, S.1    Kodet, R.2    Krskova, L.3    Vlcek, P.4    Bendlova, B.5
  • 26
    • 9444249981 scopus 로고    scopus 로고
    • Screening of six risk exons of the RET proto-oncogene in families with medullary thyroid carcinoma in the Czech Republic
    • Jindrichova S., Vcelak J., Vlcek P., Neradilova M., Nemec J., and Bendlova B. Screening of six risk exons of the RET proto-oncogene in families with medullary thyroid carcinoma in the Czech Republic. J. Endocrinol. 183 (2004) 257-265
    • (2004) J. Endocrinol. , vol.183 , pp. 257-265
    • Jindrichova, S.1    Vcelak, J.2    Vlcek, P.3    Neradilova, M.4    Nemec, J.5    Bendlova, B.6
  • 27
    • 0031980975 scopus 로고    scopus 로고
    • 27 bp deletion in the RET proto-oncogene as a somatic mutation associated with medullary thyroid carcinoma
    • Kalinin V., and Frilling A. 27 bp deletion in the RET proto-oncogene as a somatic mutation associated with medullary thyroid carcinoma. J. Mol. Med. 76 (1998) 365-367
    • (1998) J. Mol. Med. , vol.76 , pp. 365-367
    • Kalinin, V.1    Frilling, A.2
  • 30
    • 0029118799 scopus 로고
    • Analysis of RET protooncogene point mutations distinguishes heritable from nonheritable medullary thyroid carcinomas
    • Komminoth P., Kunz E.K., Matias-Guiu X., Hiort O., Christiansen G., Colomer A., Roth J., and Heitz P.U. Analysis of RET protooncogene point mutations distinguishes heritable from nonheritable medullary thyroid carcinomas. Cancer 76 (1995) 479-489
    • (1995) Cancer , vol.76 , pp. 479-489
    • Komminoth, P.1    Kunz, E.K.2    Matias-Guiu, X.3    Hiort, O.4    Christiansen, G.5    Colomer, A.6    Roth, J.7    Heitz, P.U.8
  • 34
  • 35
    • 23444437050 scopus 로고    scopus 로고
    • Searching for non-RET molecular alterations in medullary thyroid carcinoma: expression analysis by mRNA differential display
    • Musholt T.J., Hanack J., Brehm C., von Wasielewski R., and Musholt P.B. Searching for non-RET molecular alterations in medullary thyroid carcinoma: expression analysis by mRNA differential display. World J. Surg. 29 (2005) 472-482
    • (2005) World J. Surg. , vol.29 , pp. 472-482
    • Musholt, T.J.1    Hanack, J.2    Brehm, C.3    von Wasielewski, R.4    Musholt, P.B.5
  • 36
    • 0036008485 scopus 로고    scopus 로고
    • The finding of a somaticdeletion in RET exon 15 clarified the sporadic nature of amedullary thyroid carcinoma suspected to be familial
    • Oriola J., Halperin I., Rivera-Fillat F., and Donis-Keller H. The finding of a somaticdeletion in RET exon 15 clarified the sporadic nature of amedullary thyroid carcinoma suspected to be familial. J. Endocrinol. Invest. 25 (2002) 25-31
    • (2002) J. Endocrinol. Invest. , vol.25 , pp. 25-31
    • Oriola, J.1    Halperin, I.2    Rivera-Fillat, F.3    Donis-Keller, H.4
  • 37
    • 0029986851 scopus 로고    scopus 로고
    • Somatic mutations of the ret protooncogene in sporadic medullary thyroid carcinoma are not restricted to exon 16 and are associated with tumor recurrence
    • Romei C., Elisei R., Pinchera A., Ceccherini I., Molinaro E., Mancusi F., Martino E., Romeo G., and Pacini F. Somatic mutations of the ret protooncogene in sporadic medullary thyroid carcinoma are not restricted to exon 16 and are associated with tumor recurrence. J. Clin. Endocrinol. Metab. 81 (1996) 1619-1622
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 1619-1622
    • Romei, C.1    Elisei, R.2    Pinchera, A.3    Ceccherini, I.4    Molinaro, E.5    Mancusi, F.6    Martino, E.7    Romeo, G.8    Pacini, F.9
  • 38
    • 0034839109 scopus 로고    scopus 로고
    • Germline sequence variant S836S in the RET proto-oncogene is associated with low level predisposition to sporadic medullary thyroid carcinoma in the Spanish population
    • Ruiz A., Antinolo G., Fernandez R.M., Eng C., Marcos I., and Borrego S. Germline sequence variant S836S in the RET proto-oncogene is associated with low level predisposition to sporadic medullary thyroid carcinoma in the Spanish population. Clin. Endocrinol. (Oxf.) 55 (2001) 399-402
    • (2001) Clin. Endocrinol. (Oxf.) , vol.55 , pp. 399-402
    • Ruiz, A.1    Antinolo, G.2    Fernandez, R.M.3    Eng, C.4    Marcos, I.5    Borrego, S.6
  • 46
    • 0028101170 scopus 로고
    • Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTCs
    • Zedenius J., Wallin G., Hamberger B., Nordenskjöld M., Weber G., and Larsson C. Somatic and MEN 2A de novo mutations identified in the RET proto-oncogene by screening of sporadic MTCs. Hum. Mol. Genet. 3 (1994) 1259-1262
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1259-1262
    • Zedenius, J.1    Wallin, G.2    Hamberger, B.3    Nordenskjöld, M.4    Weber, G.5    Larsson, C.6


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