Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 1, 2008, Pages 310-319

  Lall, Marilyn M ^a   Ferrell, Jenny ^a   Nagar, Steve ^a   Fleisher, Lloyd N ^a   McGahan, M Christine ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; CYSTEINE; GLUTAMIC ACID; GLUTATHIONE; IRON; TRANSFERRIN; 2,2' BIPYRIDINE; AMINO ACID TRANSPORTER; CHELATING AGENT; CYSTINE; ENZYME INHIBITOR; HOLOTRANSFERRIN; MESSENGER RNA; OXALIC ACID DERIVATIVE; OXALOMALIC ACID; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; LENS EPITHELIUM; LIGHT CHAIN; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CELL CULTURE; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENETICS; LENS; METABOLISM;

2,2'-DIPYRIDYL; ACONITATE HYDRATASE; AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; CELLS, CULTURED; CHELATING AGENTS; CYSTINE; CYTOSOL; DOGS; ENZYME INHIBITORS; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; GLUTATHIONE; IMMUNOBLOTTING; LENS, CRYSTALLINE; OXALATES; PIGMENT EPITHELIUM OF EYE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFERRIN;

EID: 39549114487     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-1041     Document Type: Article

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