Glutamate/aspartate supplementation during cardiopulmonary bypass: Effect on postoperative neurocognitive function

Heart Surgery Forum

Volumn 11, Issue 1, 2008, Pages 17-20

  Erol, Demet Dogan ^a,b   Ibis, Halil Arif ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b NONE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CARDIOPLEGIC AGENT; GLUTAMIC ACID;

ADULT; AGED; ARTICLE; CARDIOPLEGIA; CARDIOPULMONARY BYPASS; CARDIOVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CRYSTALLOID; ELECTIVE SURGERY; HUMAN; MINI MENTAL STATE EXAMINATION; NEUROPROTECTION; OUTCOME ASSESSMENT; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

AGED; ASPARTIC ACID; CARDIOPULMONARY BYPASS; COGNITION; COGNITION DISORDERS; DIETARY SUPPLEMENTS; FEMALE; GLUTAMIC ACID; HEALTH STATUS INDICATORS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; POSTPARTUM PERIOD; PSYCHOLOGICAL TESTS; PSYCHOMETRICS; RISK FACTORS;

EID: 39449132423     PISSN: 10983511     EISSN: None     Source Type: Journal    
DOI: 10.1532/HSF98.20071169     Document Type: Article

References (23)

1. Arrowsmith JE, Harrison MJG, Newman SP, et al. 1998. Neuroprotection of the brain during cardiopulmonary bypass: a randomized trial of remacemide during coronary artery bypass in 171 patients. Stroke 29:2357-5.
2. Bach-y-Rita P. 2002. Volume transmission and brain plasticity. Evolution Cognition 8:115-7.
3. Bhudia SK, Cosgrove DM, Naugle RI, et al. 2006. Magnesium as a neuroprotectant in cardiac surgery: A randomized clinical trial. J Thorac Cardiovasc Surg 131:853-8.
4. Bronster DJ. 2006 Neurologic complications of cardiac surgery: current concepts and recent advances. Curr Cardiol Rep 8:9-7.
5. Browne SM, Halligan PW, Wade DT, et al. 1999. Cognitive performance after cardiac operation: implications of regression toward the mean. J Thorac Cardiovasc Surg 117:481-4.
6. Bruno V, Copani A, Knopfel T, et al. 1995. Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology 34:1089-9.
7. Burker EJ, Blumenthal JA, Feldman M, et al. 1995. The Mini Mental State Exam as a predictor of neuropsychological functioning after cardiac surgery. Int J Psychiatry Med 25:263-13.
8. Butterworth J, Hammon JW. 2002. Lidocaine for neuroprotection: more evidence of efficacy. Anesth Analg 95:1131-2.
9. Gladstone DJ, Black SE, Hakim AM. 2002. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 33:2123-3
10. Hindman BJ, Todd MM. 1999. Improving neurologic outcome after cardiac surgery. Anesthesiology 90:1243-4.
11. King N, McGivan JD, Griffiths EJ, et al. 2003. Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation. J Mol Cell Cardiol 35:975-9.
12. Lewis MS, Maruff PT, Silbert BS. 2005. Examination of the use of cognitive domains in postoperative cognitive dysfunction after coronary artery bypass graft. Ann Thorac Surg 80:910-6.
13. Nagels W, Demeyere R, Hemelrijck JV, et al. 2004. Evaluation of the neuroprotective effects of S(+)-ketamine during open-heart surgery. Anesth Analg 98:1595-8.
14. Newman MF, Croughwell ND, Blumenthal JA, et al. 1996. Cardiopulmonary bypass and the central nervous system: potential for cerebral protection. J Clin Anesth 8(3 Suppl):53-7.
15. Newman S. 1995. Analysis and interpretation of neuropsychologic tests in cardiac surgery. Ann Thorac Surg 59:1351-4.
16. Ozyurt E, Graham DI, Woodruff GN. 1988. Protective effect of the glutamate antagonist MK801 in focal cerebral ischaemia in the cat. J Cereb Blood Flow Metab 8:138-5.
17. Pugsley W, Klinger L, Paschalis, et al. 1994. The impact of microemboli in cardiopulmonary bypass on neuropsychological functioning. Stroke 25:1393-6.
18. Smith HC, Hacke W, Hennerici M, et al. 1996. Lubeluzole in acute ischaemic stroke. Stroke 27:76-5.
19. Smith P, Treasure T, Newman S, et al. 1986. Cerebral consequences of cardiopulmonary bypass. Lancet 1:823-2.
20. Smith QR. 2000. Transport of glutamate and other amino acids at the blood-brain barrier. J Nutr 130:1016-6.
21. Stump D. 1995. Selection and clinical significance of neuropsychologic tests. Ann Thorac Surg 59:1340-4.
22. Vizi ES. 2000. Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in central nervous system. Pharmacol Rev 52:63-27.
23. Weissrock S, Levy F, Balabaud V et al. 2005. Interest of the Mini Mental State Examination to detect cognitive defects after cardiac surgery. Ann Fr Anesth Reanim 24(10):1255-6.