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Volumn 2, Issue 6, 2005, Pages 561-565

One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using ZnCl2, CuCl2, NiCl2 and CoCl2 doped hydroxyapatite

Author keywords

Biginelli reaction; Dihydropyrimidinones; Heterogeneous catalysis; Hydroxyapatite; Lewis acids

Indexed keywords


EID: 39449125062     PISSN: 15701786     EISSN: None     Source Type: Journal    
DOI: 10.2174/1570178054640750     Document Type: Review
Times cited : (18)

References (29)
  • 29
    • 46149096860 scopus 로고    scopus 로고
    • Mp 209-2 10 °C; 1H NMR (DMSO-d6, 300 MHz, 1. 12 (t, J, 7,2 Hz, 3H, 2.29 (s, 3H, 4.02 (q, J, 7,2 Hz, 2H, 5.19 (d, J, 2.7 Hz, 1H, 7.27-7.42 (m, 5H, 7.76 (s, NH, 9.21 (s, NH, 13C NMR (DMSO-d6, 75 MHz, 14.1, 17.9, 54.2, 59.3, 99.5, 126.4, 127.4, 128.5, 145.0, 148.5, 152.3, 165.5. HR-FAB-MS: calc. for C14H17 O3N2 (261.30, 261.1239, M+H, 100, found: 261.1233, 2b) Mp 213-214 °C; 1HNMR(DMSO-d6, 300MHz, 1.09 (t, J, 6.7 Hz, 3H, 2.24 (s, 3H, 3.97 (q, J, 6.7 Hz, 2H, 5.14 (d, J, 3.1 Hz, 1H, 7.23 (d, J, 7,3 Hz, 2H, 7.38 (d, J, 7,3 Hz, 2H, 7.76 (s, NH, 9.23 (s, NH, 13C NMR (DMSO-d6, 75 MHz, 14.9, 18.7, 54.3, 60.1, 99.7, 129.0, 129.2, 132.7, 144.6, 149.6, 152.8, 166.2. HR-FAB-MS: calc. for C14H16 O3N2CI (295.75, 295.0849, M+H, 100, found: 295.0840, 2c) Mp
    • +, 34%).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.