Detection of numerical aberrations of chromosomes 7 and 8 in sperms of workers exposed to benzene series by two-color fluorescence in situ hybridization

Chinese Journal of Medical Genetics

Volumn 21, Issue 4, 2004, Pages 360-364

  Zhao, Ting ^a   Liu, Xin Xia ^a   He, Yun ^a   Deng, Li Xia ^a   Zheng, Lu Kang ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Benzene; Numerical chromosome aberrations; Spermatozoa; Two color fluorescence in situ hybridization

Indexed keywords

BENZENE;

ARTICLE; CHINESE; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME ABERRATION; CLINICAL ARTICLE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; MALE; MULTICOLOR FLUORESCENCE IN SITU HYBRIDIZATION; OCCUPATIONAL EXPOSURE; SPERMATOZOON; TWO COLOR FLUORESCENCE IN SITU HYBRIDIZATION;

ADULT; BENZENE; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 7; CHROMOSOMES, HUMAN, PAIR 8; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; OCCUPATIONAL DISEASES; OCCUPATIONAL EXPOSURE; SPERMATOZOA;

EID: 3943056059     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Robbins WA, Meistrich ML, Moore D. Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm. Nat Genet, 1997, 16: 74-78.
2. IARC. Monographs on the evaluation of carcinogenesis risk of chemicals to humans. Lyon, 1982, 29: 93.
3. Nie YJ. The investigations of the frequencies of sponetaneous abortions of benzene, xylene-exposed workers. Occupational Med, 1986, 13: 60.
4. Zhang L, Wang Y, Shang N, et al. Benzene metabolites induce the loss and long arm deletion of chromosomes 5 and 7 in human lymphocytes. Leuk Res, 1998, 22: 105-113.
5. Zhang L, Rothman N, Wang Y, et al. Benzene increases aneuploidy in the lymphocytes of exposed workers, a comparison of data obtained by fluorescence in situ hybridization in interphase and metaphase cells. Environ Mol Mutagen, 1999, 34: 260-268.
6. Liu SQ, Zheng LK, Deng LX, et al. Detection of aneuploidies in sperm of benzene-exposed workers using two-color fluorescence in situ hybridization. Chin J Prevent Med, 2000, 34: 17-19.
7. Li X, Zheng LK, Deng LX, et al. Detection of aneuploidies for chromosome 9, 18 in sperm of benzene-exposed workers using two-color fluorescence in situ hybridization. Acta Genet Sinica, 2001, 28: 589-594.
8. Zeng NH, Peng GF, Yang AC. The urinary trans-trans muconic acid (ttMA) as bio-monitoring indicator. Chin J Prevent Med, 1995, 29: 377-378.
9. Zheng LK, Liu SQ, Deng LX, et al. Using the method of two color fluorescence in situ hybridization to detect aneuploidy of human sperms. Chin J Med Genet, 1999, 16: 116-118.
10. Shi Q, Martin RH. Aneuploidy in human sperm, a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors. Cytogenet Cell Genet, 2000, 90: 219-226.
11. Guttenbach M, Engel W, Schmid M. Analysis of structural and numerical chromosome abnormalities in sperm of normal men and carriers of constitutional chromosome aberrations: review. Hum Genet, 1997, 100: 1-21.
12. Zhang L, Venkatesh P, Creek ML, et al. Detection of 1,2,4-benzenetriol induced aneuploidy and microtubule disruption by fluorescence in situ hybridization and immunocytochemistry. Mutat Res, 1994, 320: 315-327.