Detection of numerical chromosome aberrations in sperm of workers exposed to benzene series by two-color fluorescence in situ hybridization

Acta Genetica Sinica

Volumn 28, Issue 7, 2001, Pages 593-594

  Li, Xin ^a   Zheng, Lü Kang ^a   Deng, Li Xia ^a   Zhang, Qiao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Aneuploidy; Benzene; Fluorescence in situ hybridization; Spermatozoa

Indexed keywords

BENZENE;

ARTICLE; CHROMOSOME 18; CHROMOSOME 9; CHROMOSOME ABERRATION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; MALE; OCCUPATIONAL EXPOSURE; SPERMATOZOON; ULTRASTRUCTURE;

BENZENE; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 9; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; OCCUPATIONAL EXPOSURE; SPERMATOZOA;

EID: 0035229742     PISSN: 03794172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Mailhes J B et al. Chemically induced anuploidy in mammalian oocytes. Mutat. Res., 1994, 320:87-111.
2. Leopardi P, Zijno A, Bassani B et al. in vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells. Mutat. Res., 1993, 287:119-130.
3. Bishop J B, Dellarco V I, Hassold T et al. Aneuploidy in Germ Cells: Etiologies and Risk Factors. Environ. Mol. Mutagea., 1996, 28:159-166.
4. Robbins W A, Vine M G, Truong et al. Using of fluorescence in situ hybridization to assess coffee and alcohol on aneuploidy load in sperm of healthy men. Environ. Mol. Mutagen., 1997, 30(2): 175-183.
5. Wyrobek A J, Rubes J, Cassel M et al. Smokers produce more aneuploid sperm than non-smokers. Am. J. Hum. Genet., 1995, 57:A737.
6. Robbins W A, Meistrich M L, Moore D. Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm. Nature Genetics, 1997, 16:74-78.
7. Zhang L P et al. Detection of 1, 2, 4-benzenetriol induced aneuploidy and microtubule disruption by fluorescence in situ hybridization and immunocytochemistry. Mutat. Res., 1994, 320:315-327.
8. Zhang L P, Rothman N, Wang Y et al. Interphase Cytogenetics of Workers Exposed to Benzene. Environ. Health. Perspect., 1996, 104(supp16): 1325-1329.
9. Zhang L P, Rothman N, Wang Y et al. Benzene increases aneuploidy in the lymphocytes of exposed workers: a comparison of date obtained by fluorescence in situ hybridization in interphase and metaphase cells. Envioron. Mol. Mutagen., 1999, 34(4): 260-268.
10. CHIN
11. CHIN
12. CHIN
13. CHIN
14. Guttenbach M et al. Analysis of structural and numerical chromosome abnormalities in sperm of normal men and carriers of constitutional chromosome aberrations. A review Hum. Genet., 1997, 100:1-21.
15. Nise G, Hogstedt B, Bratt I et al. Cytogenetic effects in rotogravure printers exposed to toluene (and benzene). Mutat. Res., 1991, 261:217-223.