Differential expression of D-type cyclins in HaCat keratinocytes and in psoriasis

Journal of Investigative Dermatology

Volumn 128, Issue 3, 2008, Pages 634-642

  Belsõ, Nóra ^a   Széll, Márta ^b   Pivarcsi, Andor ^b   Kis, Kornélia ^c   Kormos, Bernadett ^a   Kenderessy, Anna Sz ^a   Dobozy, Attila ^a,b   Kemény, Lajos ^a,b   Bata Csörgõ, Zsuzsanna ^a,b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA5 INTEGRIN; CYCLIN D1; CYCLIN D2; CYCLIN D3; MESSENGER RNA; NEUTRALIZING ANTIBODY;

ARTICLE; BASEMENT MEMBRANE; CELL COUNT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL METABOLISM; CELL PROLIFERATION; CELL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWN REGULATION; EPIDERMIS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; KNOCKOUT GENE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSORIASIS;

BIOPSY; CELL DIVISION; CELL LINE, TRANSFORMED; CYCLIN D; CYCLIN D2; CYCLIN D3; CYCLINS; EPIDERMIS; G0 PHASE; G1 PHASE; GENE EXPRESSION; HUMANS; INTEGRIN ALPHA5; KERATINOCYTES; PSORIASIS; RNA, MESSENGER; S PHASE;

EID: 39149132805     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701059     Document Type: Article

References (23)

1. Aguzzi A, Brandner S, Marino S, Steinbach JP (1996) Transgenic and knockout mice in the study of neurodegenerative diseases. J Mol Med 74:111-26
2. 1/S transition and high abundance in quiescent tissues suggest a dual role in proliferation and differentiation. Oncogene 17:1027-37
3. Bata-Csorgo Z, Cooper KD, Ting KM, Voorhees JJ, Hammerberg C (1998) Fibronectin and alpha5 integrin regulate keratinocyte cell cycling. A mechanism for increased fibronectin potentiation of T cell lymphokine-driven keratinocyte hyperproliferation in psoriasis. J Clin Invest 101:1509-18
4. Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD (1993) Flow cytometric identification of proliferative subpopulations within normal human epidermis and the localization of the primary hyperproliferative population in psoriasis. J Exp Med 178:1271-81
5. Bata-Csorgo Z, Cooper KD, Kang BK, Voorhees JJ, Hammerberg C (1996) Differential expression suggesting differential functions of D-type cyclins in normal human keratinocytes. J Invest Dermatol 106:828
6. Burnworth B, Popp S, Stark HJ, Steinkraus V, Brocker EB, Hartschuh W et al. (2006) Gain of 11q/cyclin D1 overexpression is an essential early step in skin cancer development and causes abnormal tissue organization and differentiation. Oncogene 25:4399-412
7. Carroll JM, Romero MR, Watt FM (1995) Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 83:957-68
8. Carthon BC, Neumann CA, Das M, Pawlyk B, Li T, Geng Y et al. (2005) Genetic replacement of cyclin D1 function in mouse development by cyclin D2. Mol Cell Biol 25:1081-8
9. Chung JH, Ostrowski MC, Romigh T, Minaguchi T, Waite KA, Eng C (2006) The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Hum Mol Genet 15:2553-9
10. Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH et al. (2002) Development of mice expressing a single D-type cyclin. Genes Dev 16:3277-89
11. Diehl JA, Cheng M, Roussel MF, Sherr CJ (1998) Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 12:3499-511
12. Okabe H, Lee SH, Phuchareon J, Albertson DG, McCormick F, Tetsu O (2006) A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation. PLoS ONE 1:e128
13. Pellegrini G, De Luca M, Orecchia G, Balzac F, Cremona O, Savoia P et al. (1992) Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin. J Clin Invest 89:1783-95
14. Pivarcsi A, Szell M, Kemeny L, Dobozy A, Bata-Csorgo Z (2001) Serum factors regulate the expression of the proliferation- related genes alpha5 integrin and keratin 1, but not keratin 10, in HaCaT keratinocytes. Arch Dermatol Res 293:206-13
15. Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, Sicinski P et al. (1998) Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev 12:2469-74
16. Sherr CJ, Roberts JM (2004) Living with or without cyclins and cyclin-dependent kinases. Genes Dev 18:2699-711
17. Sonkoly E, Bata-Csorgo Z, Pivarcsi A, Polyanka H, Kenderessy-Szabo A, Molnar G et al. (2005) Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS. J Biol Chem 280:24159-67
18. Szell M, Bata-Csorgo Z, Koreck A, Pivarcsi A, Polyanka H, Szeg C et al. (2004) Proliferating keratinocytes are putative sources of the psoriasis susceptibility-related EDA (extra domain A of fibronectin) oncofetal fibronectin. J Invest Dermatol 123:537-46
19. Ting KM, Rothaupt D, McCormick TS, Hammerberg C, Chen G, Gilliam AC et al. (2000) Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin. J Invest Dermatol 114:706-11
20. Wang X, Sun P, Al Qamari A, Tai T, Kawashima I, Paller AS (2001) Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function. J Biol Chem 276:8436-44
21. Xu X, Lyle S, Liu Y, Solky B, Cotsarelis G (2003) Differential expression of cyclin D1 in the human hair follicle. Am J Pathol 163:969-78
22. Yamamoto H, Ochiya T, Takeshita F, Toriyama-Baba H, Hirai K, Sasaki H et al. (2002) Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation. Cancer Res 62:1641-7
23. Yang W, Zhang Y, Li Y, Wu Z, Zhu D (2007) Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1. J Biol Chem 282:3799-808