Mycophenolate mofetil restores renal function and spares steroids during idiopathic nephrotic syndrome in children. A cohort study;Le mycophénolate mofétil améliore la fonction rénale et l'imprégnation cortisonique au cours du syndrome néphrotique corticodépendant de l'enfant. Une étude de cohorte

Nephrologie et Therapeutique

Volumn 4, Issue 1, 2008, Pages 15-20

  Cailliez, Mathilde ^a   Bruno, Danièle ^a   Daniel, Laurent ^a   Afaneti, Mickaël ^b   Bérard, Etienne ^b   Sarles, Jacques ^a   Tsimaratos, Michel ^a  

^a TIMONE HOSPITAL   (France)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE NICE   (France)

Author keywords

Body mass index; Cyclosporine; Idiopathic nephrotic syndrome; Mycophenolate Mofetil; Nephrotoxicity; Renal function; Steroid dependant

Indexed keywords

CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID;

ARTICLE; BODY MASS; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GLOMERULOPATHY; HUMAN; KIDNEY FUNCTION; MALE; NEPHROTIC SYNDROME; NEPHROTOXICITY; RELAPSE; REMISSION;

EID: 39149122813     PISSN: 17697255     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nephro.2007.09.005     Document Type: Article

References (27)

1. Antignac C. Genetic models: clues for understanding the pathogenesis of idiopathic nephrotic syndrome. J Clin Invest 109 4 (2002 Feb) 447-449
2. Frange P., Frey M.A., and Deschenes G. Immunity and immunosuppression in childhood idiopathic nephrotic syndrome. Arch Pediatr 12 3 (2005 Mar) 305-315
3. Fakhouri F., Bocquet N., Taupin P., Presne C., Gagnadoux M.F., Landais P., et al. Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 41 3 (2003 Mar) 550-557
4. Habib R., and Niaudet P. Comparison between pre- and posttreatment renal biopsies in children receiving ciclosporine for idiopathic nephrosis. Clin Nephrol 42 3 (1994 Sep) 141-146
5. Bagga A., Hari P., Moudgil A., and Jordan S.C. Mycophenolate mofetil and prednisolone therapy in children with steroid-dependent nephrotic syndrome. Am J Kidney Dis 42 6 (2003 Dec) 1114-1120
6. Barletta G.M., Smoyer W.E., Bunchman T.E., Flynn J.T., and Kershaw D.B. Use of mycophenolate mofetil in steroid-dependent and -resistant nephrotic syndrome. Pediatr Nephrol 18 8 (2003 Aug) 833-837
7. Gellermann J., and Querfeld U. Frequently relapsing nephrotic syndrome: treatment with mycophenolate mofetil. Pediatr Nephrol 19 1 (2004 Jan) 101-104
8. Moudgil A., Bagga A., and Jordan S.C. Mycophenolate mofetil therapy in frequently relapsing steroid-dependent and steroid-resistant nephrotic syndrome of childhood: current status and future directions. Pediatr Nephrol 20 10 (2005 Oct) 1376-1381
9. Novak I., Frank R., Vento S., Vergara M., Gauthier B., and Trachtman H. Efficacy of mycophenolate mofetil in pediatric patients with steroid-dependent nephrotic syndrome. Pediatr Nephrol 20 9 (2005 Sep) 1265-1268
10. Ulinski T., Dubourg L., Said M.H., Parchoux B., Ranchin B., and Cochat P. Switch from cyclosporine A to mycophenolate mofetil in nephrotic children. Pediatr Nephrol 20 4 (2005 Apr) 482-485
11. Allison A.C., and Eugui E.M. Mycophenolate mofetil and its mechanisms of action. Immunopharmacology 47 2-3 (2000 May) 85-118
12. Chan T.M., Tse K.C., Tang C.S., Mok M.Y., and Li F.K. Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis. J Am Soc Nephrol 16 4 (2005 Apr) 1076-1084
13. Choi M.J., Eustace J.A., Gimenez L.F., Atta M.G., Scheel P.J., Sothinathan R., et al. Mycophenolate mofetil treatment for primary glomerular diseases. Kidney Int 61 3 (2002 Mar) 1098-1114
14. Contreras G., Pardo V., Leclercq B., Lenz O., Tozman E., O'Nan P., et al. Sequential therapies for proliferative lupus nephritis. N Engl J Med 350 10 (2004 Mar 4) 971-980
15. Loirat C., Baudouin V., Cloarec S., and Peuchmaur M. Treatment of nephrosis in the child. Arch Pediatr 5 Suppl 2 (1998) 142s-149s
16. Rolland-Cachera M.F., Cole T.J., Sempe M., Tichet J., Rossignol C., and Charraud A. Body mass index variations: centiles from birth to 87 years. Eur J Clin Nutr 45 1 (1991 Jan) 13-21
17. Schwartz G.J., Brion L.P., and Spitzer A. The use of plasma creatinine concentration for estimating glomerular filtration rate in infants, children, and adolescents. Pediatr Clin North Am 34 3 (1987 Jun) 571-590
18. Niaudet P., and Habib R. Cyclosporine in the treatment of idiopathic nephrosis. J Am Soc Nephrol 5 4 (1994 Oct) 1049-1056
19. Niaudet P., Tete M.J., Broyer M., and Habib R. Cyclosporine and childhood idiopathic nephrosis. Transplant Proc 20 3 Suppl 4 (1988 Jun) 265-268
20. Ettenger R., and Sarwal M.M. Mycophenolate mofetil in pediatric renal transplantation. Transplantation 80 2 Suppl (2005 Oct 15) S201-S210
21. Briggs W.A., Choi M.J., and Scheel Jr. P.J. Successful mycophenolate mofetil treatment of glomerular disease. Am J Kidney Dis 31 2 (1998 Feb) 213-217
22. Chan T.M., Li F.K., Tang C.S., Wong R.W., Fang G.X., Ji Y.L., et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong-Guangzhou nephrology study group. N Engl J Med 343 16 (2000 Oct 19) 1156-1162
23. Badid C., Vincent M., McGregor B., Melin M., Hadj-Aissa A., Veysseyre C., et al. Mycophenolate mofetil reduces myofibroblast infiltration and collagen III deposition in rat remnant kidney. Kidney Int 58 1 (2000 Jul) 51-61
24. Dubus I., Vendrely B., Christophe I., Labouyrie J.P., Delmas Y., Bonnet J., et al. Mycophenolic acid antagonizes the activation of cultured human mesangial cells. Kidney Int 62 3 (2002 Sep) 857-867
25. Mohacsi P.J., Tuller D., Hulliger B., and Wijngaard P.L. Different inhibitory effects of immunosuppressive drugs on human and rat aortic smooth muscle and endothelial cell proliferation stimulated by platelet-derived growth factor or endothelial cell growth factor. J Heart Lung Transplant 16 5 (1997 May) 484-492
26. Shihab F.S., Bennett W.M., Yi H., Choi S.O., and Andoh T.F. Mycophenolate mofetil ameliorates arteriolopathy and decreases transforming growth factor-beta 1 in chronic cyclosporine nephrotoxicity. Am J Transplant 3 12 (2003 Dec) 1550-1559
27. Yang C.W., Ahn H.J., Kim W.Y., Li C., Kim H.W., Choi B.S., et al. Cyclosporine withdrawal and mycophenolate mofetil treatment effects on the progression of chronic cyclosporine nephrotoxicity. Kidney Int 62 1 (2002 Jul) 20-30