메뉴 건너뛰기




Volumn 68, Issue 1, 2008, Pages 285-291

Differential involvement of vascular endothelial growth factor in the survival of hypoxic colon cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; FLT1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; PHOSPHOLIPASE C GAMMA; UNCLASSIFIED DRUG; VASCULOTROPIN A;

EID: 39149122201     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5564     Document Type: Article
Times cited : (70)

References (28)
  • 1
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 2
    • 13444278498 scopus 로고    scopus 로고
    • Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies
    • Gerber HP, Ferrara N. Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies. Cancer Res 2005;65:671-80.
    • (2005) Cancer Res , vol.65 , pp. 671-680
    • Gerber, H.P.1    Ferrara, N.2
  • 3
    • 0036780251 scopus 로고    scopus 로고
    • Clinical translation of angiogenesis inhibitors
    • Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2002;2:727-39.
    • (2002) Nat Rev Cancer , vol.2 , pp. 727-739
    • Kerbel, R.1    Folkman, J.2
  • 4
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
    • Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307:58-62.
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 5
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 2004;25:581-611.
    • (2004) Endocr Rev , vol.25 , pp. 581-611
    • Ferrara, N.1
  • 6
    • 0034693879 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis
    • Karkkainen MJ, Petrova TV. Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis. Oncogene 2000;19:5598-605.
    • (2000) Oncogene , vol.19 , pp. 5598-5605
    • Karkkainen, M.J.1    Petrova, T.V.2
  • 8
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 2005;23:1011-27.
    • (2005) J Clin Oncol , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 9
    • 20944441857 scopus 로고    scopus 로고
    • Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells
    • Fan F, Wey JS, McCarty MF, et al. Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells. Oncogene 2005;24:2647-53.
    • (2005) Oncogene , vol.24 , pp. 2647-2653
    • Fan, F.1    Wey, J.S.2    McCarty, M.F.3
  • 10
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Hockel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 2001;93:266-76.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 11
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia-a key regulatory factor in tumour growth
    • Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 13
    • 33749362031 scopus 로고    scopus 로고
    • Inhibiting hypoxia-inducible factor 1 for cancer therapy
    • Melillo G. Inhibiting hypoxia-inducible factor 1 for cancer therapy. Mol Cancer Res 2006;4:601-5.
    • (2006) Mol Cancer Res , vol.4 , pp. 601-605
    • Melillo, G.1
  • 14
    • 33645504221 scopus 로고    scopus 로고
    • Hypoxic induction of an HIF-1α-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells
    • Calvani M, Rapisarda A, Uranchimeg B, Shoemaker RH, Melillo G. Hypoxic induction of an HIF-1α-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells. Blood 2006;107:2705-12.
    • (2006) Blood , vol.107 , pp. 2705-2712
    • Calvani, M.1    Rapisarda, A.2    Uranchimeg, B.3    Shoemaker, R.H.4    Melillo, G.5
  • 15
    • 1242271198 scopus 로고    scopus 로고
    • Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: Mechanism and therapeutic implications
    • Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker RH, Melillo G. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res 2004;64:1475-82.
    • (2004) Cancer Res , vol.64 , pp. 1475-1482
    • Rapisarda, A.1    Uranchimeg, B.2    Sordet, O.3    Pommier, Y.4    Shoemaker, R.H.5    Melillo, G.6
  • 16
    • 0034065028 scopus 로고    scopus 로고
    • VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells
    • Li W, Keller G. VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells. J Cell Sci 2000;113:1525-34.
    • (2000) J Cell Sci , vol.113 , pp. 1525-1534
    • Li, W.1    Keller, G.2
  • 17
    • 33747165872 scopus 로고    scopus 로고
    • Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments
    • Lampugnani MG, Orsenigo F, Gagliani MC, Tacchetti C, Dejana E. Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments. J Cell Biol 2006;174:593-604.
    • (2006) J Cell Biol , vol.174 , pp. 593-604
    • Lampugnani, M.G.1    Orsenigo, F.2    Gagliani, M.C.3    Tacchetti, C.4    Dejana, E.5
  • 18
    • 0036009760 scopus 로고    scopus 로고
    • VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding
    • Soker S, Miao HQ, Nomi M, Takashima S, Klagsbrun M. VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding. J Cell Biochem 2002;85:357-68.
    • (2002) J Cell Biochem , vol.85 , pp. 357-368
    • Soker, S.1    Miao, H.Q.2    Nomi, M.3    Takashima, S.4    Klagsbrun, M.5
  • 19
    • 12644271905 scopus 로고    scopus 로고
    • Wild-type p53 is not sufficient for serum starvation-induced apoptosis in cancer cells but accelerates apoptosis in sensitive cells
    • Blagosklonny MV, Wu GS, Somasundaram K, ElDeiry WS. Wild-type p53 is not sufficient for serum starvation-induced apoptosis in cancer cells but accelerates apoptosis in sensitive cells. Int J Oncol 1997;11:1165-70.
    • (1997) Int J Oncol , vol.11 , pp. 1165-1170
    • Blagosklonny, M.V.1    Wu, G.S.2    Somasundaram, K.3    ElDeiry, W.S.4
  • 20
    • 33749028188 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signaling pathways: Therapeutic perspective
    • Kowanetz M, Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006;12:5018-22.
    • (2006) Clin Cancer Res , vol.12 , pp. 5018-5022
    • Kowanetz, M.1    Ferrara, N.2
  • 21
    • 0033118228 scopus 로고    scopus 로고
    • VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
    • Takahashi T, Ueno H, Shibuya M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 1999;18:2221-30.
    • (1999) Oncogene , vol.18 , pp. 2221-2230
    • Takahashi, T.1    Ueno, H.2    Shibuya, M.3
  • 22
    • 0035355472 scopus 로고    scopus 로고
    • A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells
    • Takahashi T, Yamaguchi S, Chida K, Shibuya M. A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-γ and DNA synthesis in vascular endothelial cells. EMBO J 2001;20:2768-78.
    • (2001) EMBO J , vol.20 , pp. 2768-2778
    • Takahashi, T.1    Yamaguchi, S.2    Chida, K.3    Shibuya, M.4
  • 23
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996;380:439-42.
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 24
    • 33644822574 scopus 로고    scopus 로고
    • The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells
    • Su JL, Yang PC, Shih JY, et al. The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell 2006;9:209-23.
    • (2006) Cancer Cell , vol.9 , pp. 209-223
    • Su, J.L.1    Yang, P.C.2    Shih, J.Y.3
  • 25
    • 34247527730 scopus 로고    scopus 로고
    • Hypoxia-inducible factors, stem cells, and cancer
    • Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007;129:465-72.
    • (2007) Cell , vol.129 , pp. 465-472
    • Keith, B.1    Simon, M.C.2
  • 26
    • 33644747418 scopus 로고    scopus 로고
    • HIF-2α regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
    • Covello KL, Kehler J, Yu H, et al. HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 2006;20:557-70.
    • (2006) Genes Dev , vol.20 , pp. 557-570
    • Covello, K.L.1    Kehler, J.2    Yu, H.3
  • 27
    • 0033674846 scopus 로고    scopus 로고
    • Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression
    • Miao HQ, Lee P, Lin H, Soker S, Klagsbrun M. Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression. FASEB J 2000;14:2532-9.
    • (2000) FASEB J , vol.14 , pp. 2532-2539
    • Miao, H.Q.1    Lee, P.2    Lin, H.3    Soker, S.4    Klagsbrun, M.5
  • 28
    • 0037115522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4
    • Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002;62:7203-6.
    • (2002) Cancer Res , vol.62 , pp. 7203-7206
    • Bachelder, R.E.1    Wendt, M.A.2    Mercurio, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.