Anxiolytic-like effects of DOI microinjections into the hippocampus (but not the amygdala nor the PAG) in the mice four plates test

Behavioural Brain Research

Volumn 188, Issue 2, 2008, Pages 291-297

  Masse, Fabienne ^a   Petit Demouliere, Benoit ^a   Dubois, Isabelle ^a   Hascoët, Martine ^a   Bourin, Michel ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

Amygdala; Anxiety; DOI; FPT; GABA; Hippocampus; Mice; PAG

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; APPARATUS; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG MECHANISM; FOUR PLATES TEST; HIPPOCAMPUS; LOCOMOTION; MALE; MOUSE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PSYCHOLOGIC TEST; SWISS WEBSTER MOUSE; TRANQUILIZING ACTIVITY;

AMPHETAMINES; AMYGDALA; ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; MALE; MICE; MICROINJECTIONS; MOTOR ACTIVITY; PERIAQUEDUCTAL GRAY;

EID: 39149117007     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2007.11.005     Document Type: Article

References (62)

1. Amano K., Tanikawa T., Iseki H., Kawabatake H., Notani M., Kawamura H., et al. Single neuron analysis of the human midbrain tegmentum. Rostral mecencephalic reticulotomy for pain relief. Appl Neurophysiol 41 (1978) 66-78
2. Antoniadis E.A., and McDonald R.J. Amygdala, hippocampus and discriminative fear conditioning to context. Behav Brain Res 108 (2000) 1-19
3. Aron C., Simon P., Larousse C., and Boissier J.R. Evaluation of a rapid technique for detecting minor tranquilizers. Neuropharmacology 10 (1971) 459-469
4. Azmitia E.C., and Segal M. An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat. J Comp Neurol 179 (1978) 641-667
5. Bandler R., and Shipley M.T. Columnar organization in the midbrain periaqueductal gray: modules for emotional expression?. Trends Neurosci 17 (1994) 379-389
6. Bannerman D.M., Grubb M., Deacon R.M., Yee B.K., Feldon J., and Rawlins J.N. Ventral hippocampal lesions affect anxiety but not spatial learning. Behav Brain Res 139 (2003) 197-213
7. Beekman M., Flachskamm C., and Linthorst A.C. Effects of exposure to a predator on behaviour and serotonergic neurotransmission in different brain regions of C57bl/6N mice. Eur J Neurosci 21 (2005) 2825-2836
8. Belzung C., El Hage W., Moindrot N., and Griebel G. Behavioral and neurochemical changes following predatory stress in mice. Neuropharmacology 41 (2001) 400-408
9. Blanchard D.C., and Blanchard R.J. Innate and conditioned reactions to threat in rats with amygdaloid lesions. J Comp Physiol Psychol 81 (1972) 281-290
10. Boissier J.R., Simon P., and Aron C. A new method for rapid screening of minor tranquillizers in mice. Eur J Pharmacol 4 (1968) 145-151
11. Bourin M., Hascoet M., Mansouri B., Colombel M.C., and Bradwejn J. Comparison of behavioral effects after single and repeated administrations of four benzodiazepines in three mice behavioral models. J Psychiatry Neurosci 17 (1992) 72-77
12. Bourin M., and Nic Dhonnchadha B.A. 5-HT2 receptors and anxiety. Drug Dev Res 65 (2005) 133-140
13. Brandao M.L., Troncoso A.C., de Souza Silva M.A., and Huston J.P. The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations. Eur J Pharmacol 463 (2003) 225-233
14. Campbell B.M., and Merchant K.M. Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment. Brain Res 993 (2003) 1-9
15. Campeau S., Hayward M.D., Hope B.T., Rosen J.B., Nestler E.J., and Davis M. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear. Brain Res 565 (1991) 349-352
16. Carvalho M.C., Albrechet-Souza L., Masson S., and Brandao M.L. Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test. Braz J Med Biol Res 38 (2005) 1857-1866
17. Cornelio A.M., and Nunes-de-Souza R.L. Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze. Behav Brain Res 178 (2007) 82-89
18. de Bortoli V.C., Nogueira R.L., and Zangrossi Jr. H. Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray. Psychopharmacology (Berl) 183 (2006) 422-428
19. de Mello Cruz A.P., Pinheiro G., Alves S.H., Ferreira G., Mendes M., Faria L., et al. Behavioral effects of systemically administered MK-212 are prevented by ritanserin microinfusion into the basolateral amygdala of rats exposed to the elevated plus-maze. Psychopharmacology (Berl) 182 (2005) 345-354
20. de Paula Soares V., and Zangrossi Jr. H. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain Res Bull 64 (2004) 181-188
21. Dringenberg H.C., Kornelsen R.A., Pacelli R., Petersen K., and Vanderwolf C.H. Effects of amygdaloid lesions, hippocampal lesions, and buspirone on black-white exploration and food carrying in rats. Behav Brain Res 96 (1998) 161-172
22. Franklin K, Paxinos G. The Mouse Brain in Stereotaxic Coordinates, 1997.
23. Gerlai R. Behavioral tests of hippocampal function: simple paradigms complex problems. Behav Brain Res 125 (2001) 269-277
24. Goldstein L.E., Rasmusson A.M., Bunney B.S., and Roth R.H. Role of the amygdala in the coordination of behavioral, neuroendocrine, and prefrontal cortical monoamine responses to psychological stress in the rat. J Neurosci 16 (1996) 4787-4798
25. Graeff F.G. Brain defense systems of anxiety. BGaNJR handbook of anxiety. The neurobiology of anxiety (1990), Elsevier Science Publishers, Amsterdam 307-54
26. Hackler E.A., Turner G.H., Gresch P.J., Sengupta S., Deutch A.Y., Avison M.J., et al. 5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation. J Pharmacol Exp Ther 320 (2007) 1023-1029
27. Halasy K., Miettinen R., Szabat E., and Freund T.F. GABAergic Interneurons are the Major Postsynaptic Targets of Median Raphe Afferents in the Rat Dentate Gyrus. Eur J Neurosci 4 (1992) 144-153
28. Hascoet M., Bourin M., Colombel M.C., Fiocco A.J., and Baker G.B. Anxiolytic-like effects of antidepressants after acute administration in a four-plate test in mice. Pharmacol Biochem Behav 65 (2000) 339-344
29. Higgins G.A., Jones B.J., Oakley N.R., and Tyers M.B. Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists. Psychopharmacology (Berl) 104 (1991) 545-551
30. Hodges H., Green S., and Glenn B. Evidence that the amygdala is involved in benzodiazepine and serotonergic effects on punished responding but not on discrimination. Psychopharmacology (Berl) 92 (1987) 491-504
31. Jacob C.A., Cabral A.H., Almeida L.P., Magierek V., Ramos P.L., Zanoveli J.M., et al. Chronic imipramine enhances 5-HT(1A) and 5-HT(2) receptors-mediated inhibition of panic-like behavior in the rat dorsal periaqueductal gray. Pharmacol Biochem Behav 72 (2002) 761-766
32. Jenck F., Broekkamp C.L., and Van Delft A.M. Effects of serotonin receptor antagonists on PAG stimulation induced aversion: different contributions of 5HT1, 5HT2 and 5HT3 receptors. Psychopharmacology (Berl) 97 (1989) 489-495
33. Kataoka Y., Shibata K., Miyazaki A., Inoue Y., Tominaga K., Koizumi S., et al. Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic. Neuropharmacology 30 (1991) 475-480
34. Lee K., Dixon A.K., and Pinnock R.D. Serotonin depolarizes hippocampal interneurones in the rat stratum oriens by interaction with 5HT2 receptors. Neurosci Lett 270 (1999) 56-58
35. Lovick T.A. The periaqueductal gray-rostral medulla connection in the defence reaction: efferent pathways and descending control mechanisms. Behav Brain Res 58 (1993) 19-25
36. Luttgen M., Ove Ogren S., and Meister B. Chemical identity of 5-HT2A receptor immunoreactive neurons of the rat septal complex and dorsal hippocampus. Brain Res 1010 (2004) 156-165
37. Mamounas L.A., Mullen C.A., O'Hearn E., and Molliver M.E. Dual serotoninergic projections to forebrain in the rat: morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives. J Comp Neurol 314 (1991) 558-586
38. Masse F., Hascoet M., and Bourin M. Effect of GABAergic ligands on the anxiolytic-like activity of DOI (a 5-HT(2A/2C) agonist) in the four-plate test in mice. Eur Neuropsychopharmacol 17 (2007) 483-491
39. McQuade R., and Sharp T. Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis. J Neurochem 69 (1997) 791-796
40. Menard J., and Treit D. Effects of centrally administered anxiolytic compounds in animal models of anxiety. Neurosci Biobehav Rev 23 (1999) 591-613
41. Menard J., and Treit D. The septum and the hippocampus differentially mediate anxiolytic effects of R(+)-8-OH-DPAT. Behav Pharmacol 9 (1998) 93-101
42. Moore R.Y., Halaris A.E., and Jones B.E. Serotonin neurons of the midbrain raphe: ascending projections. J Comp Neurol 180 (1978) 417-438
43. Nashold Jr. B.S., Wilson W.P., and Slaughter D.G. Sensations evoked by stimulation in the midbrain of man. J Neurosurg 30 (1969) 14-24
44. Nazar M., Siemiatkowski M., Czlonkowska A., Sienkiewicz-Jarosz H., and Plaznik A. The role of the hippocampus and 5-HT/GABA interaction in the central effects of benzodiazepine receptor ligands. J Neural Transm 106 (1999) 369-381
45. Nic Dhonnchadha B.A., Bourin M., and Hascoet M. Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety. Behav Brain Res 140 (2003) 203-214
46. Nic Dhonnchadha B.A., Hascoet M., Jolliet P., and Bourin M. Evidence for a 5-HT2A receptor mode of action in the anxiolytic-like properties of DOI in mice. Behav Brain Res 147 (2003) 175-184
47. Nic Dhonnchadha B.A., Ripoll N., Clenet F., Hascoet M., and Bourin M. Implication of 5-HT2 receptor subtypes in the mechanism of action of antidepressants in the four plates test. Psychopharmacology (Berl) 179 (2005) 418-429
48. Onaivi E.S., Bishop-Robinson C., Darmani N.A., and Sanders-Bush E. Behavioral effects of (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze test. Life Sci 57 (1995) 2455-2466
49. Plaznik A., Jessa M., Bidzinski A., and Nazar M. The effect of serotonin depletion and intra-hippocampal midazolam on rat behavior in the Vogel conflict test. Eur J Pharmacol 257 (1994) 293-296
50. Pompeiano M., Palacios J.M., and Mengod G. Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors. Brain Res Mol Brain Res 23 (1994) 163-178
51. Rex A., Voigt J.P., and Fink H. Anxiety but not arousal increases 5-hydroxytryptamine release in the rat ventral hippocampus in vivo. Eur J Neurosci 22 (2005) 1185-1189
52. Ripoll N., Hascoet M., and Bourin M. The four-plates test: anxiolytic or analgesic paradigm?. Prog Neuropsychopharmacol Biol Psychiatry 30 (2006) 873-880
53. Rodgers R.J., Johnson N.J.T., Norton S.J., and Cole J.C. Effects of ritanserin and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) in the murine elevated plus-maze test of anxiety: an ethopharmacological study. J Psychopharmacol 9 (1995) 38-42
54. Sanders M.J., Wiltgen B.J., and Fanselow M.S. The place of the hippocampus in fear conditioning. Eur J Pharmacol 463 (2003) 217-223
55. Schutz M.T., de Aguiar J.C., and Graeff F.G. Anti-aversive role of serotonin in the dorsal periaqueductal grey matter. Psychopharmacology (Berl) 85 (1985) 340-345
56. Seeman P., Westman K., Coscina D., and Warsh J.J. Serotonin receptors in hippocampus and frontal cortex. Eur J Pharmacol 66 (1980) 179-191
57. Shen R.Y., and Andrade R. 5-Hydroxytryptamine2 receptor facilitates GABAergic neurotransmission in rat hippocampus. J Pharmacol Exp Ther 285 (1998) 805-812
58. Stefanski R., Palejko W., Bidzinski A., Kostowski W., and Plaznik A. Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A receptor agonists. Neuropharmacology 32 (1993) 977-985
59. Treit D., and Menard J. Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions. Behav Neurosci 111 (1997) 653-658
60. Vertes R.P. A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat. J Comp Neurol 313 (1991) 643-668
61. Whitton P., and Curzon G. Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus. Psychopharmacology (Berl) 100 (1990) 138-140
62. Zangrossi Junior H., and Graeff F.G. Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze. Braz J Med Biol Res 27 (1994) 2453-2456