Effects of amygdaloid lesions, hippocampal lesions, and buspirone on black-white exploration and food carrying in rats

Behavioural Brain Research

Volumn 96, Issue 1-2, 1998, Pages 161-172

  Dringenberg, Hans C ^a,b   Kornelsen, Rick A ^a   Pacelli, Robert ^a   Petersen, Karin ^a   Vanderwolf, C H ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

5 HT(1A) receptor; Amygdala; Anxiety; Buspirone; Hippocampus; Rat; Serotonin

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; BRAIN INJURY; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACOUSTIC STIMULATION; AMYGDALA; ANIMALS; BUSPIRONE; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; HIPPOCAMPUS; MALE; RATS; SEROTONIN AGONISTS;

EID: 0032212442     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(98)00010-2     Document Type: Article

References (79)

1. Azmitia E.C., Segal M. An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat. J Comp Neurol. 179:1978;641-668.
2. Bindra D. What makes rats hoard? J Comp Physiol Psychol. 41:1948;397-402.
3. Blanchard D.C., Blanchard R.J. Innate and conditioned reactions to threat in rats with amygdaloid lesions. J Comp Psychol. 81:1972;281-290.
4. Bolhuis J.J., Fitzgerald R.E., Dijk D.L., Koolhaas J.M. The corticomedial amygdala and learning in an agonistic situation in the rat. Physiol Behav. 32:1984;575-579.
5. Cain D.P., Bindra D. Responses of amygdala single units to odors in the rat. Exp Neurol. 35:1972;98-110.
6. Carli M., Prontera C., Samanin R. Evidence that central 5-hydroxytryptaminergic neurones are involved in the anxiolytic activity of buspirone. Br J Pharmacol. 96:1989;829-836.
7. Clark M., Fletcher A. Does buspirone elicit feeding by a similar mechanism to that of 8-OH-DPAT? Br J Pharmacol. 89:1986;863P.
8. Crawley J., Goodwin F.K. Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines. Pharmacol Biochem Behav. 13:1980;167-170.
9. Davies M. The role of the amygdala in conditioned fear. In: Aggleton JP, editor. The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. New York: Wiley-Liss, 1992:255-305.
10. Davies M. The role of the amygdala in fear and anxiety. Ann Rev Neurosci. 15:1992;353-375.
11. De Olmos J, Alheid GF, Beltramino CA. Amygdala. In: Paxinos G, editor. The Rat Nervous System, Vol. 1, Forebrain and Midbrain. Sydney: Academic Press, 1985:223-334.
12. Dringenberg H.C., Kornelsen R.A., Vanderwolf C.H. Food carrying in rats is blocked by the putative anxiolytic agent buspirone. Pharmacol Biochem Behav. 49:1994;741-746.
13. Eison A.S., Eison M.S., Stanley M., Riblet L.A. Serotonergic mechanisms in the behavioral effects of buspirone and gepirone. Pharmacol Biochem Behav. 24:1986;701-707.
14. Eison A.S., Temple D.L. Buspirone: review of its pharmacology and current perspectives on the mechanism of action. Am J Med. 80(Suppl 3B):1989;1-9.
15. Fanselow MS. The midbrain periaqueductal gray as a coordinator of action in response to fear and anxiety. In: Depaulis A, Bandler R, editors. The Midbrain Periaqueductal Grey Matter: Functional, Anatomical and Immunohistochemical Organization. New York: Plenum Publishing Organization, 1991:151-173.
16. Fantino M., Cabanac M. Body weight regulation with a proportional hoarding response in the rat. Physiol Behav. 24:1980;939-942.
17. Fernandez-Guasti A., Lopez-Rubalcava C., Perez-Urizar J., Castaneda-Hernandez G. Evidence for a postsynaptic action of the serotonergic anxiolytics: ipsapirone, indorenate and buspirone. Brain Res Bull. 28:1992;497-501.
18. 3 receptor antagonist BRL 46470A. Neuropsychobiology. 33:1996;189-195.
19. Geller I., Hartmann R.J. Effects of buspirone on operant behavior of laboratory rats and cynomolgus monkeys. J Clin Psychiatry. 43:1982;25-32.
20. Glaser T., Traber J. Buspirone: action on serotonin receptors in calf hippocampus. Eur J Pharmacol. 88:1983;137-138.
21. Gloor P. Amygdala. In: Field J, Magoun HW, Hall VE, editors. Handbook of Physiology, Section 1: Neurophysiology, vol. II. Washington: American Physiological Society, 1960:1395-1420.
22. Goldberg A.L., Finnerty R.J. The comparative efficacy of buspirone and diazepam in the treatment of anxiety. Am J Psychiatry. 136:1979;1184-1187.
23. Gray JA. The Neuropsychology of Anxiety. New York: Oxford University Press, 1982.
24. Halgren E. Emotional neurophysiology of the amygdala within the context of human cognition. In: Aggleton JP, editor. The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. New York: Wiley-Liss, 1992:191-228.
25. 3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain. J Neurochem. 44:1985;1685-1696.
26. Horel J.A. Some comments on the special cognitive functions claimed for the hippocampus. Cortex. 30:1994;269-280.
27. Horel J.A., Keating E.G., Misantone L.J. Partial Klüver-Bucy syndrome produced by destroying temporal neocortex or amygdala. Brain Res. 94:1975;347-359.
28. Kimble D.P. The effects of bilateral hippocampal lesions in rats. J Comp Physiol Psychol. 56:1963;273-283.
29. LeDoux JE. Emotion and the amygdala. In: Aggleton JP, editor. The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. New York: Wiley-Liss, 1992:339-351.
30. Lima S.L. Maximizing feeding efficiency and minimizing time exposed to predators: a trade-off in the black-capped chickadee. Oecologia (Berlin). 66:1985;60-67.
31. Lima S.L., Valone T.J., Caraco T. Foraging-efficiency-risk trade-off in the grey squirrel. Anim Behav. 33:1985;155-165.
32. Luiten P.G.M., Koolhaas J.M., deBoer S., Koopmans S.J. The corticomedial amygdala in the central nervous system organization of agonistic behavior. Brain Res. 332:1985;283-297.
33. MacLean P.D. The limbic system ('visceral brain') and emotional behavior. Arch Neurol Psychiatry. 73:1955;130-134.
34. 1A receptor ligands. Eur J Pharmacol. 156:1988;375-383.
35. Martin J.R., Moreau J.-L., Jenck F., Cumin R. Acute and chronic administration of buspirone fails to yield anxiolytic-like effects in a mouse operant punishment paradigm. Pharmacol Biochem Behav. 46:1993;905-910.
36. McCleary R.A., Morgan C.T. Food hoarding in rats as a function of environmental temperature. J Comp Psychol. 39:1946;371-378.
37. McNamara R.K., Whishaw I.Q. Blockade of hoarding in rats by diazepam: an analysis of the anxiety and object value hypotheses of hoarding. Psychopharmacology. 101:1990;214-221.
38. Merlo Pich E., Samanin R. Disinhibitory effects of buspirone and low doses of sulpiride and haloperidol in two experimental anxiety models in rats: possible role of dopamine. Psychopharmacology. 89:1986;125-130.
39. Miller G.A., Viek P. An analysis of the rat's response to unfamiliar aspects of the hoarding situation. J Comp Psychol. 37:1944;221-231.
40. Nagy J., Zambo K., Decsi L. Anti-anxiety action of diazepam after intra-amygdaloid application in the rat. Neuropharmacology. 18:1979;573-576.
41. Oddie SD, Kirk IJ, Whishaw IQ, Bland BH. The hippocampal formation is involved in movement selection: evidence from medial septal cholinergic modulation and concurrent slow-wave (theta rhythm) recording. Behav Brain Res 1997;88:169-80.
42. Oddie S.D., Stefanek W., Kirk I.J., Bland B.H. Intraseptal procaine abolishes hypothalamic stimulation-induced wheel-running and hippocampal theta field activity in rats. J Neurosci. 16:1996;1948-1956.
43. Palacios J.M., Waeber C., Hoyer D., Mengod G. Distribution of serotonin receptors. Ann New York Acad Sci. 600:1990;36-52.
44. Papez J.W. A proposed mechanism of emotion. Arch Neurol Psychiatry. 38:1937;725-744.
45. Pazos A., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res. 346:1985;205-230.
46. 1A receptors. Biol Psychiatry. 20:1985;971-979.
47. Pollard G.T., Howard J.L. Cork gnawing in the rat as a screening method for buspirone-like anxiolytics. Drug Dev Res. 22:1991;179-187.
48. 1A receptor in the rat brain: correlation with receptor binding. J Neurosci. 12:1992;440-453.
49. Roberts W.W., Dember W.N., Brodwick M. Alternation and exploration in rats with hippocampal lesions. J Comp Physiol Psychol. 55:1962;695-700.
50. 1A receptors play an important role in modulation of behavior of rats in a two-compartment black and white box. Behav Pharmacol. 7:1996;788-797.
51. Schacter G.B., Phelps M.T., Brobeck D.R., Mogenson G.J., Roberts W.A. Disruption of central-place foraging in the rat following lesions of the dorsomedial thalamic nucleus. Psychobiology. 19:1991;91-99.
52. Stamm J.S. Control of hoarding activity in rats by the median cerebral cortex. J Comp Physiol Psychol. 47:1954;21-27.
53. Steinbusch HWM, Nieuwenhuys R. The raphe nuclei of the rat brainstem: a cytoarchitectonic and immunohistochemical study. In: Emson PC, editor. Chemical Neuroanatomy. New York: Raven Press, 1983:131-207.
54. Taylor D.P. Serotonin agents in anxiety. Ann New York Acad Sci. 600:1990;545-557.
55. Teitelbaum H., Milner P. Activity changes following partial hippocampal lesions in rats. J Comp Physiol Psychol. 56:1963;284-289.
56. Törk I. Anatomy of the serotonergic system. Ann New York Acad Sci. 600:1990;366-383.
57. Traber J., Glaser T. 5-HT 1A receptor-related anxiolytics. Trends Pharmacol Sci. 8:1987;432-437.
58. Treit D., Pesold C., Rotzinger S. Dissociating the anti-fear effects of septal and amygdaloid lesions using two pharmacologically validated models of rat anxiety. Behav Neurosci. 107:1993;770-785.
59. Ursin H. The effect of amygdaloid lesions on flight and defense behavior in cats. Exp Neurol. 11:1965;61-79.
60. Ursin H., Kaada B.R. Functional localization within the amygdaloid complex in the cat. Electroenceph Clin Neurophysiol. 12:1960;1-20.
61. VanderMaelen C.P., Matheson G.K., Wilderman R.C., Patterson L.A. Inhibition of serotonergic dorsal raphe neurons by systemic and iontophoretic administration of buspirone, a non-benzodiazepine anxiolytic drug. Eur J Pharmacol. 129:1986;123-130.
62. Vanderwolf C.H. Neocortical and hippocampal activation in relation to behavior: effects of atropine, phenothiazines, and amphetamine. J Comp Physiol Psychol. 88:1975;300-323.
63. Vanderwolf CH. Brain, behavior, and mind: what do we know and what can we know? Neurosci Biobehav Rev (in press).
64. Vanderwolf C.H., Kelley M.E., Kraemer P., Streather A. Are emotion and motivation localized in the limbic system and nucleus accumbens? Behav Brain Res. 27:1988;45-58.
65. Wallace R.J., Tinger J.C. Effects of cortical and hippocampal lesions on hoarding behavior in the albino rat. Physiol Behav. 8:1972;937-942.
66. Wheatley D. Buspirone: Multicenter efficacy study. J Clin Psychiatry. 43:1982;92-94.
67. Whishaw I.Q. Hippocampal electroencephalographic activity in the mongolian gerbil during natural behaviours and wheel running and in the rat during wheel running and conditioned immobility. Can J Psychol. 26:1972;219-239.
68. Whishaw I.Q. A simple behavioral paradigm for the study of Type I hippocampal rhythmical slow activity (RSA) frequency shifts. Physiol Behav. 29:1982;751-753.
69. Whishaw I.Q. Time estimates contribute to food handling decisions by rats: implications for neural control of hoarding. Psychobiology. 18:1990;460-466.
70. Whishaw I.Q. Activation, travel distance, and environmental change influence food carrying in rats with hippocampal, medial thalamic and septal lesions: implications for studies on hoarding and theories of hippocampal function. Hippocampus. 3:1993;373-385.
71. Whishaw I.Q., Dringenberg H.C. How dies the rat (Rattus norvegicus) adjust food-carrying responses to the influence of distance, effort, predatory odor, food size, and food availability? Psychobiology. 19:1991;251-261.
72. Whishaw I.Q., Gorney B.P., Dringenberg H.C. The defensive strategies of foraging rats: a review and synthesis. Psychol Rec. 41:1991;185-205.
73. Whishaw I.Q., Oddie S.D., McNamara R.K., Harris T.L., Perry B.S. Psychophysical methods for study of sensory-motor behavior using a food-carry (Hoarding) task in rodents. J Neurosci Methods. 32:1990;123-133.
74. Whishaw I.Q., Tomie J. Food-pellet size modifies the hoarding behavior of foraging rats. Psychobiology. 17:1989;93-101.
75. Whishaw I.Q., Tomie J. Olfaction directs skilled forelimb reaching in the rat. Behav Brain Res. 32:1989;11-21.
76. Whishaw I.Q., Whishaw G.E. Conspecific aggression influences food carrying: studies on a wild population of Rattus norvegicus. Aggressive Behav. 22:1996;47-66.
77. Wilkinson L.O., Auerbach S.B., Jacobs B.L. Extracellular serotonin levels change with behavioral state but not with pyrogen-induced hyperthermia. J Neurosci. 11:1991;2732-2741.
78. Wilkinson LO, Dourish CT. Serotonin and animal behavior. In: Peroutka SJ, editor. Serotonin Receptor Subtypes: Basic and Clinical Aspects. New York: Wiley-Liss, 1991:147-210.
79. Wishart T., Brohman L., Mogenson G. Effects of lesions of the hippocampus and septum on hoarding behavior. Anim Behav. 17:1969;781-784.