Absence of endogenous interleukin-10 enhanced organ dysfunction and mortality associated to zymosan-induced multiple organ dysfunction syndrome

Cytokine

Volumn 41, Issue 2, 2008, Pages 136-143

  Malleo, Giuseppe ^a   Mazzon, Emanuela ^a,b   Genovese, Tiziana ^a,b   Di Paola, Rosanna ^a,b   Caminiti, Rocco ^a   Esposito, Emanuela ^b,c   Bramanti, Placido ^b   Cuzzocrea, Salvatore ^a,b  

^a UNIVERSITY OF MESSINA   (Italy)

^b IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cytokines; IL 10; Knockout mice; Leukocytes; Multiple organ dysfunction syndrome

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; MALONALDEHYDE; MYELOPEROXIDASE; NITROGEN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN;

ACUTE PHASE RESPONSE; ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; ILEUM; KIDNEY FAILURE; KNOCKOUT MOUSE; LEUKOCYTE ACTIVATION; LIPID PEROXIDATION; LIVER FAILURE; LUNG; MORTALITY; MOUSE; MULTIPLE ORGAN FAILURE; NONHUMAN; OVERALL SURVIVAL; PANCREAS INSUFFICIENCY; PERITONEUM EXUDATE; PRIORITY JOURNAL; SURVIVAL RATE; WILD TYPE;

ANIMALS; GENE DELETION; INTERLEUKIN-10; INTERLEUKIN-1BETA; KIDNEY; LIPID PEROXIDATION; LIVER; MICE; MICE, KNOCKOUT; MULTIPLE ORGAN FAILURE; NEUTROPHIL INFILTRATION; NITRATES; NITRITES; PANCREAS; PERITONITIS; TUMOR NECROSIS FACTOR-ALPHA; ZYMOSAN;

ANIMALIA; MUS;

EID: 39149110579     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2007.11.003     Document Type: Article

References (19)

1. Imperatore F., Cuzzocrea S., De Lucia D., Sessa M., Rinaldi B., Capuano A., et al. Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome. Intensive Care Med 32 (2006) 1881-1888
2. Dugo L., Chatterjee P.K., Mazzon E., McDonald M.C., Di Paola R., Fulia F., et al. The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat. Intensive Care Med 28 (2002) 775-778
3. Malleo G., Mazzon E., Siriwardena A.K., and Cuzzocrea S. Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence. Shock 28 (2007) 130-140
4. Cuzzocrea S., Rossi A., Pisano B., Di Paola R., Genovese T., Patel N.S., et al. Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice. Intensive Care Med 29 (2003) 2016-2025
5. Keel M., Ungethum U., Steckholzer U., Niederer E., Hartung T., Trentz O., et al. Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis. Blood 90 (1997) 3356-3363
6. Ajuebor M.N., Das A.M., Virag L., Flower R.J., Szabo C., and Perretti M. Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10. J Immunol 162 (1999) 1685-1691
7. Volman T.J., Goris R.J., van der Meer J.W., and Hendriks T. Tissue- and time-dependent upregulation of cytokine mRNA in a murine model for the multiple organ dysfunction syndrome. Ann Surg 240 (2004) 142-150
8. Ferrer T.J., Webb J.W., Wallace B.H., Bridges C.D., Palmer H.E., Robertson R.D., et al. Interleukin-10 reduces morbidity and mortality in murine multiple organ dysfunction syndrome (MODS). J Surg Res 77 (1998) 157-164
9. Jansen M.J., Hendriks T., de Man B.M., van der Meer J.W., and Goris R.J. Interleukin 10 mitigates the development of the zymosan-induced multiple organ dysfunction syndrome in mice. Cytokine 11 (1999) 713-721
10. McAuliffe P.F., Murday M.E., Efron P.A., Scumpia P.O., Ungaro R., Abouhamze A., et al. Dose-dependent improvements in outcome with adenoviral expression of interleukin-10 in a murine model of multisystem organ failure. Gene Ther 13 (2006) 276-282
11. Du Z., Kelly E., Mecklenbrauker I., Agle L., Herrero C., Paik P., et al. Selective regulation of IL-10 signaling and function by zymosan. J Immunol 176 (2006) 4785-4792
12. Tilg H., van Montfrans C., van den Ende A., Kaser A., van Deventer S.J., Schreiber S., et al. Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma. Gut 50 (2002) 191-195
13. Fedorak R.N., Gangl A., Elson C.O., Rutgeerts P., Schreiber S., Wild G., et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The interleukin 10 inflammatory bowel disease cooperative study group. Gastroenterology 119 (2000) 1473-1482
14. Di Paola R., Esposito E., Mazzon E., Genovese T., Muià C., Crisafulli C., et al. Absence of peroxisome proliferators-activated receptors (PPAR)-alpha enhanced the multiple organ failure induced by zymosan. Shock 26 (2006) 477-484
15. Cuzzocrea S., Mazzon E., Dugo L., Barbera A., Centorrino T., Ciccolo A., et al. Inducible nitric oxide synthase knock out mice exhibit a resistance to multiple organ failure induced by zymosan. Shock 16 (2001) 51-58
16. Samarasinghe R., Tailor P., Tamura T., Kaisho T., Akira S., and Ozato K. Induction of an anti-inflammatory cytokine, IL-10, in dendritic cells after toll-like receptor signaling. J Interferon Cytokine Res 26 (2006) 893-900
17. Kabay B., Kocaefe C., Baykal A., Ozden H., Baycu C., Oner Z., et al. Interleukin-10 gene transfer: prevention of multiple organ injury in a murine cecal ligation and puncture model of sepsis. World J Surg 31 (2007) 105-115
18. Cuzzocrea S., Imperatore F., Costantino G., Luongo C., Mazzon E., Scafuro M.A., et al. Role of hyperbaric oxygen exposure in reduction of lipid peroxidation and in multiple organ failure induced by zymosan administration in the rat. Shock 13 (1999) 197-203
19. Cuzzocrea S., Filippelli A., Zingarelli B., Falciani M., Caputi A.P., and Rossi F. Role of nitric oxide in a nonseptic shock model induced by zymosan in the rat. Shock 7 (1997) 351-357