Variable-length poly-C tract polymorphisms of the β2- adrenergic receptor 3′-UTR alter expression and agonist regulation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 2, 2008, Pages

  Panebra, Alfredo ^a   Schwarb, Mary Rose ^a   Swift, Steven M ^a   Weiss, Scott T ^b   Bleecker, Eugene R ^c   Hawkins, Gregory A ^c   Liggett, Stephen B ^a,d  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d HSF II   (United States)

Author keywords

agonist; Asthma; Transcription

Indexed keywords

ARGININE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; DACTINOMYCIN; MESSENGER RNA; POLYCYTIDYLIC ACID;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENETIC TRANSFECTION; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; INTRON; MUCOCILIARY CLEARANCE; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR GENE; REGULATORY MECHANISM; RESPIRATORY EPITHELIUM; SMOOTH MUSCLE FIBER; WILD TYPE;

3' UNTRANSLATED REGIONS; ADRENERGIC BETA-AGONISTS; CELL LINE; GENE EXPRESSION REGULATION; HAPLOTYPES; HUMANS; OPEN READING FRAMES; POLY C; POLYMORPHISM, GENETIC; RECEPTORS, ADRENERGIC, BETA-2; RNA STABILITY; RNA, MESSENGER;

EID: 39149091039     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00277.2007     Document Type: Article

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