Attenuation of biochemical parameters in streptozotocin-induced diabetic rats by oral administration of extracts and fractions of Cephalotaxus sinensis

Journal of Clinical Biochemistry and Nutrition

Volumn 42, Issue 1, 2008, Pages 21-28

  Saeed, Muhammad K ^a   Deng, Yulin ^a   Dai, Rongji ^a  

^a BEIJING INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Biochemical parameters; Cephalotaxus sinensis; Hepato renal effects; HPLC; STZ induced diabetic rats

Indexed keywords

ACETIC ACID ETHYL ESTER; ALANINE AMINOTRANSFERASE; ALCOHOL; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BUTANOL; CEPHALOTAXUS SINENSIS EXTRACT; CREATININE; FLAVONOID; GLUCOSE; ORAL ANTIDIABETIC AGENT; SAPONIN DERIVATIVE; STEROL DERIVATIVE; STREPTOZOCIN; TERPENE DERIVATIVE; TOLBUTAMIDE; UNCLASSIFIED DRUG; UREA; WATER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CEPHALOTAXUS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG EFFECT; FEMALE; GLUCOSE URINE LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IN VIVO STUDY; LIVER PROTECTION; MALE; NONHUMAN; RAT; RENAL PROTECTION; STREPTOZOCIN DIABETES; TOXICITY TESTING; UREA BLOOD LEVEL;

ANIMALIA; CEPHALOTAXUS SINENSIS; RATTUS;

EID: 39149083717     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.2008004     Document Type: Article

References (39)

1. Dahiru, D., Sini, J.M., and John-Africa, L.: Antidiarrhoeal activity of Ziziphus mauritiana root extract in rodents. Afr. J. Biotechnol., 5, 941-945, 2006.
2. Habib, M.Y., Islam, M.S., Awal M.A, ., and Khan, M.A.: Herbal Products: A Novel Approach for Diabetic Patients. Pak. J. Nutri., 4, 17-21, 2005.
3. Knight, B., Akhurst, B., Matthews, V.B., Ruddell, R.G., Ramm, G.A., Abraham, L.J., Olynyk, J.K., and Yeoh, G.C.: Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice. J. Hepato., 46, 134-141, 2007.
4. Rao, G.M., Rao, C.V., Pushpangadan, P., and Shirwaikar, A.: Hepatoprotective effects of rubiadin, a major constituent of Rubia cordifolia Linn. J. Ethno., 103, 484-490, 2006.
5. Wills, P.J. and Asha, V.V.: Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachloride-induced acute liver injury in rats. J. Ethno., 108, 320-326, 2006.
6. Editorial Board of Zhonghua Bencao, "Zhonghua Bencao", Shanghai Scientific and Technical Press, Shanghai, pp. 341-342, 1999.
7. Wang, L.-W., Su, H.-J., Yang, S.-Z., Won, S.-J., and Lin, C.-N.: New alkaloids and a tetraflavonoid from Cephalotaxus wilsoniana. J. Nat. Prod., 67, 1182-1185, 2004.
8. Bocar, M., Jossang, A., and Bodo, B.New Alkaloids from Cephalotaxus fortunei. J. Nat. Prod., 66, 152-154, 2003.
9. Du, J., Chiu, M.-H., and Nie, R.-L.: Two new lactones from Cephalotaxus fortunei var. alpnia J. Nat. Prod., 62, 1664-1665, 1999.
10. Lee, M.K., Lim, S.W., Yang, H., Sung, S.H., Lee, H.S., Park, M.J., and Kim, Y.C.Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana. Bio. Med. Chem. Lett., 16, 2850-2854, 2006.
11. Evans, W.C.: Trease and Evan's Pharmacognosy, 13th ed. Balliere Tindal, London, pp. 419-420, 1989.
12. Escarpa, A., Morales, M.D., and Gonzalez, M.C.: Analytical performance of commercially available and unavailable phenolic compounds using real samples by high-performance liquid chromatography-diode-array detection. Ana. Chim. Acta, 460, 61-72, 2002.
13. Ghosh, M.N.: Fundamentals of Experimental Pharmacology. Scientific Book Agency, Calcutta, pp. 153, 1984.
14. Turner, M.A.: Screening Methods in Pharmacology. Academic Press, New York, pp. 26, 1965.
15. Bergmeyer, H.U.: IFCC methods for the measurement of catalytic concentrations of enzymes. Part 3. IFCC method for alanine aminotransferase (1-alanine: 2-oxoglutarate aminotransferase). Clin. Chem. Acta, 105, 147-154, 1980.
16. Bergmeyer, H.U., Bowes, G.N., Jr., Horder, M., Jr., and Moss, D.W.: Provisional recommendations on IFCC methods for the measurement of catalytic concentrations of enzymes. Part 2. IFCC method for aspartate aminotransferase. Clin. Chem. Acta, 70, F19-F42, 1976.
17. Belfield, A. and Goldberg, D.M.: Colourimetric determination of alkaline phosphatase activity. Enzyme, 12, 561-568, 1971.
18. Bartels, H., and Boehmer, M.: Microdetermination of creatinine. Clin. Chim. Acta, 32, 81-85, 1971.
19. Palton, C.J. and Crouch, S.R.: Spectrophotometric and kinetics investigation of the Berthelot reaction for the determination of ammonia. Ana. Chem., 49, 464-469, 1977.
20. Gui, S.-Y., Wei, W., Wang, H., Wua, L., Suna, W.-Y., Chen, W.-B., and Wu, C.-Y.: Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats. J. Ethno., 103, 154-159, 2006.
21. Wu, J. and Danielsson, A.: Inhibition of hepatic fibrogenesis: a review of pharmacologic candidates. Scan. J. Gastro., 29, 385-391, 1994.
22. Chojkier, M. and Brenner, D.A.: Therapeutic strategies for hepatic fibrosis. Hepatology, 8, 176-182, 1988.
23. Snyder, L.R., Glajch, J.L., and Kirkland, J.J.: Practical HPLC Method Development, Wiley, New York, 1998.
24. Loomis, T.A.: Essential of Toxicology. Phil. Le., 6, 67-78, 1968.
25. Ahn, T., Yun, C.-H., and Oh, D.-B.: Tisue specific effect of ascorbic acid supplementation on the expression of cytochrom P450 2EI and oxidative stress in Streptozotocin-induced diabetic rats. Toxi. Let., 166, 27-36, 2006.
26. Sallie, R., Tredger, J.M., and William, R.: Drugs and the liver. Biopharm Drug Dispos., 12, 251-259, 1991.
27. Senthil, K.R., Ponmozhi, M., Viswanathan, P., and Nalini, N.: Activity of Cassia auriculata leaf extract in rats with alcoholic liver injury. J. Nutr. Biochem., 14, 452-458, 2003.
28. Rajesh, M.G. and Latha, M.S.: Preliminary evaluation of the antihepatotoxic effect of Kamilari, a polyherbal formulation. J. Ethno., 91, 99-104, 2004.
29. Almdal, T.P. and Vilstrup, H.: Strict insulin treatment normalizes the organic nitrogen contents and the capacity of urea-N synthesis in experimental diabetes in rats. Diab., 31, 114-118, 1988.
30. Wills, P.J. and Asha, V.V.: Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachloride-induced acute liver injury in rats. J. Ethno., 108, 320-326, 2006.
31. Yamazaki, E., Inagaki, M., Kurita, O., and Inoue, T.: Antioxidant activity of Japanese pepper (Zanthoxylum piperitum DC.) fruit. Food Chem., 100, 171-177, 2007.
32. Jaeschke, H., Gores, G.J., Cederbaum, A.I., Hinson, J.A., Pessayre, D., and Lemasters, J.J.: Mechanisms of hepatotoxicity. Toxicol. Sci., 65, 166-176, 2002.
33. Desco, M.C., Asensi, M., Marquez, R., Martinez-Valls, J., Vento, M., Pallardo, F.V., Sastre, J., and Vina, J.: Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol. Diab., 51, 1118-1124, 2002.
34. Wolff, S.P.: Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the etiology of diabetes mellitus and complications. Br. Med. Bull., 49, 642-652, 1993.
35. Takano, I., Yasuda, I., Nishijima, M., Hitotsuyanagi, Y., Takeya, K., and Itokawa, H.: Drapangtonine, a novel antileukemic alkaloid from Cephalotaxus harringtonia var. Drupacea. Bio. Med. Chem. Let., 6, 1689-1690, 1996.
36. Delfel, N.E. and Rothfus, J.A.: Antitumor alkaloids in callus cultures of Cephalotaxus harringtonia. Phytochem., 16, 1595-1598, 1977.
37. Morita, H., Arisaka, M., Yoshida, N., and Kobayashi, J.: Cephalezomines A-F, potent cytotoxic alkaloids from Cephalotaxus harringtonia var. nana. Tetra., 56, 2929-2934, 2000.
38. Han, J.: Traditional Chinese medicine and the search for new antineoplastic drugs. J. Ethno., 24, 1-17, 1988.
39. Delfel, N.E.: Alkaloid distribution and catabolism in Cephalotaxus harringtonia. Phytochm., 19, 403-408, 1980.