메뉴 건너뛰기




Volumn 121, Issue 2, 2008, Pages 147-154

Tong-xin-luo capsule inhibits left venticular remodeling in spontaneously hypertensive rats by enhancing PPAR-γ expression and suppressing NF-κB activity

Author keywords

Chinese herbal; Inbred spontaneously hypertensive rat; Nuclear factor kappa B; Peroxisome proliferator activated receptors; Ventricular remodeling

Indexed keywords

BETA ACTIN; CHINESE DRUG; COLLAGEN TYPE 1; COLLAGEN TYPE 3; HETERODIMER; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P50; SODIUM CHLORIDE; TONG XIN LUO; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

EID: 39049153969     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200801020-00011     Document Type: Article
Times cited : (11)

References (22)
  • 1
    • 38049073303 scopus 로고    scopus 로고
    • Effects of tongxinluo on the myocardial inflammatory reaction and expression of tumor necrosis factor-alpha in rats with myocardial infarction
    • Kong Q, Yang XC, Liu XL. Effects of tongxinluo on the myocardial inflammatory reaction and expression of tumor necrosis factor-alpha in rats with myocardial infarction. Chiq J Integ Trad West (Chin) 2006; 26: 545-549.
    • (2006) Chiq J Integ Trad West (Chin) , vol.26 , pp. 545-549
    • Kong, Q.1    Yang, X.C.2    Liu, X.L.3
  • 2
    • 33846414722 scopus 로고    scopus 로고
    • Effects of Tong-xin-luo and Simvastatin on the stabilization of vulnerable atherosclerotic plaques of aorta in aotic atherosclerosis and molecular mechanism: A comparative study with rabbits
    • Li Z, Yang YJ, Qin XW, Ruan YM, Chen Y, Meng L, et al. Effects of Tong-xin-luo and Simvastatin on the stabilization of vulnerable atherosclerotic plaques of aorta in aotic atherosclerosis and molecular mechanism: a comparative study with rabbits. Nat Med J China (Chin), 2006; 86: 3146-3150.
    • (2006) Nat Med J China (Chin) , vol.86 , pp. 3146-3150
    • Li, Z.1    Yang, Y.J.2    Qin, X.W.3    Ruan, Y.M.4    Chen, Y.5    Meng, L.6
  • 3
    • 39049171232 scopus 로고    scopus 로고
    • The effect of Tong Xin. Luo on vascular remodeling after angioplasty in rabbits
    • Tang YS, Cui X. The effect of Tong Xin. Luo on vascular remodeling after angioplasty in rabbits. Chin J Cardio (Chin) 2002; 32: 1147-1149.
    • (2002) Chin J Cardio (Chin) , vol.32 , pp. 1147-1149
    • Tang, Y.S.1    Cui, X.2
  • 4
    • 0346056795 scopus 로고    scopus 로고
    • Inhibitory effect of trilinolein on angiotensin II-induced cardiomyocyte hypertrophy
    • Liu JC, Cheng TH, Lee HM, Lee WS, Shih NL, Chen YL, et al. Inhibitory effect of trilinolein on angiotensin II-induced cardiomyocyte hypertrophy. Eur J Pharmocol 2004; 404: 1-8.
    • (2004) Eur J Pharmocol , vol.404 , pp. 1-8
    • Liu, J.C.1    Cheng, T.H.2    Lee, H.M.3    Lee, W.S.4    Shih, N.L.5    Chen, Y.L.6
  • 5
    • 25644432799 scopus 로고    scopus 로고
    • Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats
    • Iturbe BR, Ferrebuz A, Vanegas V, Quiroz Y, Mezzano S, Vaziri ND. Early and sustained inhibition of nuclear factor-kappaB prevents hypertension in spontaneously hypertensive rats. J Pharmacol Exp Ther 2005; 315: 51-57.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 51-57
    • Iturbe, B.R.1    Ferrebuz, A.2    Vanegas, V.3    Quiroz, Y.4    Mezzano, S.5    Vaziri, N.D.6
  • 6
    • 0036950082 scopus 로고    scopus 로고
    • Gene expression in fibroblasts and fibrosis: Involvement in cardiac hypertrophy
    • Manabe I, Shindo T, Nagai R. Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy. Circ Res 2002; 91: 1103-1113.
    • (2002) Circ Res , vol.91 , pp. 1103-1113
    • Manabe, I.1    Shindo, T.2    Nagai, R.3
  • 7
    • 0037066014 scopus 로고    scopus 로고
    • Peroxisome proliferators activated receptor γ plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo
    • Asakawa M, Takano H, Nagai T, Uozumi H, Hasegawa H, Kubota N, et al. Peroxisome proliferators activated receptor γ plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. Circulation 2002; 105: 1240-1246.
    • (2002) Circulation , vol.105 , pp. 1240-1246
    • Asakawa, M.1    Takano, H.2    Nagai, T.3    Uozumi, H.4    Hasegawa, H.5    Kubota, N.6
  • 8
    • 0037058874 scopus 로고    scopus 로고
    • Pioglitazone, a peroxisome proliferator-activated receptor agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction
    • Tetsuya S, Hiroyuki T, Shunj H. Pioglitazone, a peroxisome proliferator-activated receptor agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation 2002; 6: 3126-3132.
    • (2002) Circulation , vol.6 , pp. 3126-3132
    • Tetsuya, S.1    Hiroyuki, T.2    Shunj, H.3
  • 9
    • 0037370148 scopus 로고    scopus 로고
    • Sustained activation of nuclear factor kappa B and activator protein-1 in chronic heart failure
    • Frantz S, Fraccarollo D, Wagner H, Behr TM, Jung P, Angermann CE. Sustained activation of nuclear factor kappa B and activator protein-1 in chronic heart failure. Cardiovasc Res 2003; 57; 749-756.
    • (2003) Cardiovasc Res , vol.57 , pp. 749-756
    • Frantz, S.1    Fraccarollo, D.2    Wagner, H.3    Behr, T.M.4    Jung, P.5    Angermann, C.E.6
  • 10
    • 12244296453 scopus 로고    scopus 로고
    • Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylylcyclase
    • Swaney JS, Roth DM, Olson ER, Naugle JE, Meszaros JG, Insel PA. Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylylcyclase. Proc Natl Acad Sci USA 2005; 102: 437-442.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 437-442
    • Swaney, J.S.1    Roth, D.M.2    Olson, E.R.3    Naugle, J.E.4    Meszaros, J.G.5    Insel, P.A.6
  • 11
    • 4043127381 scopus 로고    scopus 로고
    • Valvular myofibroblast activation by transforming growth factor-beta: Implications for pathological extracellular matrix remodeling in heart valve diseases
    • Walker GA, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve diseases. Circ Res 2004; 95: 253-260.
    • (2004) Circ Res , vol.95 , pp. 253-260
    • Walker, G.A.1    Masters, K.S.2    Shah, D.N.3    Anseth, K.S.4    Leinwand, L.A.5
  • 12
    • 33645079156 scopus 로고    scopus 로고
    • Identification of differentially expressed genes induced by angiotension II in rat cardiac fibroblasts
    • Wang XF, Gao GD, Liu J, Guo R, Lin YX, Chu YL, et al. Identification of differentially expressed genes induced by angiotension II in rat cardiac fibroblasts. Clin Exp Pharmacol Phsiol 2006; 33: 41-46.
    • (2006) Clin Exp Pharmacol Phsiol , vol.33 , pp. 41-46
    • Wang, X.F.1    Gao, G.D.2    Liu, J.3    Guo, R.4    Lin, Y.X.5    Chu, Y.L.6
  • 13
    • 34548455491 scopus 로고    scopus 로고
    • Effect of tongxinluo on myocardial fibrosis in Spontaneously Hypertensive Rats
    • Wang HJ, Xie LD, Yao EH. Effect of tongxinluo on myocardial fibrosis in Spontaneously Hypertensive Rats. Chin J Integ Trad West (Chin) 2003; 1: 189-190.
    • (2003) Chin J Integ Trad West (Chin) , vol.1 , pp. 189-190
    • Wang, H.J.1    Xie, L.D.2    Yao, E.H.3
  • 14
    • 39049107878 scopus 로고    scopus 로고
    • Experimental study on depressing ventricular remodeling of rats by regulation of β-adrenoreceptor pathway with Tongxinluo
    • Chen W, Gu RY, Zhu P. Experimental study on depressing ventricular remodeling of rats by regulation of β-adrenoreceptor pathway with Tongxinluo. J Diffic and Compl Cas 2002; 1: 12-14.
    • (2002) J Diffic and Compl Cas , vol.1 , pp. 12-14
    • Chen, W.1    Gu, R.Y.2    Zhu, P.3
  • 15
    • 34548462443 scopus 로고    scopus 로고
    • Effects of Tongxinluo-facilitated cellular cardiomyoplasty with autologous bone marrow-mesenchymal stem cells on postinfarct swine hearts
    • Qian HY, Yang YJ, Huang J, Gao RL, Dou KF, Yang GS, et al. Effects of Tongxinluo-facilitated cellular cardiomyoplasty with autologous bone marrow-mesenchymal stem cells on postinfarct swine hearts. Chin Med J 2007; 120: 1416-1425.
    • (2007) Chin Med J , vol.120 , pp. 1416-1425
    • Qian, H.Y.1    Yang, Y.J.2    Huang, J.3    Gao, R.L.4    Dou, K.F.5    Yang, G.S.6
  • 16
    • 0037164814 scopus 로고    scopus 로고
    • Activation of nuclear factor kappaB is necessary for myotrophin-induced cardiac hypertrophy
    • Gupta S, Purcell NH, Lin A, Sen S. Activation of nuclear factor kappaB is necessary for myotrophin-induced cardiac hypertrophy. J Cell Biol 2002; 159: 1019-1028.
    • (2002) J Cell Biol , vol.159 , pp. 1019-1028
    • Gupta, S.1    Purcell, N.H.2    Lin, A.3    Sen, S.4
  • 17
    • 27744552036 scopus 로고    scopus 로고
    • Resolution of inflammation: Prostaglandin E2 dissociates nuclear trafficking of Individual NF-κB subunits (P65, P50) in stimulated rheumatoid synovial fibroblasts
    • Gomez PF, Pillinger MH, Attur M, Marjanovic N, Dave M, Park J, et al. Resolution of inflammation: prostaglandin E2 dissociates nuclear trafficking of Individual NF-κB subunits (P65, P50) in stimulated rheumatoid synovial fibroblasts. J Immunol 2005; 175: 6924-6930.
    • (2005) J Immunol , vol.175 , pp. 6924-6930
    • Gomez, P.F.1    Pillinger, M.H.2    Attur, M.3    Marjanovic, N.4    Dave, M.5    Park, J.6
  • 18
    • 0036544592 scopus 로고    scopus 로고
    • A novel in vivo assay for deubiquitination of 1 kappa B alpha
    • Strayhom WD, Wadzinski BE. A novel in vivo assay for deubiquitination of 1 kappa B alpha. Arch Biochem Biophys 2002; 400: 76-84.
    • (2002) Arch Biochem Biophys , vol.400 , pp. 76-84
    • Strayhom, W.D.1    Wadzinski, B.E.2
  • 19
    • 0036314839 scopus 로고    scopus 로고
    • Ligands of the peroxisome proliferators activated proliferators activated receptors (PPAR- and PPAR-α) reduce myocardial infarct size
    • Wayman NS, Hattori Y, McDonald MC, Mota-Filipe H, Cuzzocrea S. Ligands of the peroxisome proliferators activated proliferators activated receptors (PPAR- and PPAR-α) reduce myocardial infarct size. FASEB J 2002; 16: 1027-1040.
    • (2002) FASEB J , vol.16 , pp. 1027-1040
    • Wayman, N.S.1    Hattori, Y.2    McDonald, M.C.3    Mota-Filipe, H.4    Cuzzocrea, S.5
  • 20
    • 1042286369 scopus 로고    scopus 로고
    • PPAR activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats
    • Diep QN, Benkirane K, Amiri F, Cohn JS, Endemann D. PPAR activator fenofibrate inhibits myocardial inflammation and fibrosis in angiotensin II-infused rats. J Mol Cell Cardiol 2004; 36:295-304.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 295-304
    • Diep, Q.N.1    Benkirane, K.2    Amiri, F.3    Cohn, J.S.4    Endemann, D.5
  • 21
    • 85026134753 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors vascular and cardiac effects in hypertension
    • Schiffrin EL, Amiri F, Benkirane K, Iglarz M, Diep QN. Peroxisome proliferator-activated receptors vascular and cardiac effects in hypertension. Hypertension 2003; 42: 664-668.
    • (2003) Hypertension , vol.42 , pp. 664-668
    • Schiffrin, E.L.1    Amiri, F.2    Benkirane, K.3    Iglarz, M.4    Diep, Q.N.5
  • 22
    • 13544270029 scopus 로고    scopus 로고
    • Long-term effects of the PPARγ activator pioglitazone on cardiac inflammation in strokeprone spontaneously hypertensive rats
    • Quy N, Diep FA, Karim B, Pierre P. Long-term effects of the PPARγ activator pioglitazone on cardiac inflammation in strokeprone spontaneously hypertensive rats. Can J Physiol Pharmacol 2004; 82: 976-985.
    • (2004) Can J Physiol Pharmacol , vol.82 , pp. 976-985
    • Quy, N.1    Diep, F.A.2    Karim, B.3    Pierre, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.