Galactosylated low molecular weight chitosan as a carrier delivering oligonucleotides to Kupffer cells instead of hepatocytes in vivo

Journal of Biomedical Materials Research - Part A

Volumn 84, Issue 3, 2008, Pages 777-784

  Dong, Lei ^a   Gao, Shuying ^a   Diao, Huajia ^a   Chen, Jiangning ^a   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Galactosylated chitosan; Kupffer cells; Nonviral vector; Targeting delivery

Indexed keywords

GALACTOSYLATED CHITOSAN; KUPFFER CELLS; NONVIRAL VECTOR; TARGETING DELIVERY;

CELLS; DRUG DELIVERY; MOLECULAR WEIGHT; OLIGONUCLEOTIDES;

CHITOSAN;

ASIALOGLYCOPROTEIN RECEPTOR; CHITOSAN; GALACTOSYLATED LOW MOLECULAR WEIGHT CHITOSAN; LACTOSE; LECTIN; N ACETYLGALACTOSAMINE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG TARGETING; DRUG UPTAKE; ENDOCYTOSIS; KUPFFER CELL; LIVER CELL; LIVER PARENCHYMA; MACROPHAGE; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM;

ANIMALS; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GALACTOSE; HEPATOCYTES; KUPFFER CELLS; LIVER; MALE; MICE; MICE, INBRED ICR; MOLECULAR WEIGHT; OLIGONUCLEOTIDES;

EID: 39049145174     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31328     Document Type: Article

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